Page last updated: 2024-08-23

pimonidazole and Cancer of Cervix

pimonidazole has been researched along with Cancer of Cervix in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19902 (6.90)18.7374
1990's4 (13.79)18.2507
2000's18 (62.07)29.6817
2010's4 (13.79)24.3611
2020's1 (3.45)2.80

Authors

AuthorsStudies
Aarnes, EK; Evensen, TS; Fjeldbo, CS; Hillestad, T; Hompland, T; Kristensen, GB; Lund, KV; Lyng, H; Nilsen, A; Salberg, UB; Skingen, VE; Stokke, T1
Andersen, LMK; Gaustad, JV; Hauge, A; Huang, R; Rofstad, EK; Simonsen, TG; Wegner, CS1
Ellingsen, C; Galappathi, K; Hompland, T; Mathiesen, B; Rofstad, EK1
Cui, P; Dai, M; Han, J; Li, H; Liu, Q; Xiu, R; Yu, M1
Busk, M; Horsman, MR; Jakobsen, S; Mueller-Klieser, W; Overgaard, J; Steiniche, T; Walenta, S1
Ellingsen, C; Galappathi, K; Mathiesen, B; Ovrebø, KM; Rofstad, EK1
Bennewith, KL; Durand, RE; Raleigh, JA1
Airley, RE; Davidson, SE; Harris, AL; Hunter, RD; Loncaster, J; Raleigh, JA; Stratford, IJ; West, CM1
Aquino-Parsons, C; Chou, SC; Davidson, SE; Havsteen, H; Hunter, R; Ladekarl, M; Lindegaard, JC; Loncaster, J; Nordsmark, M; Overgaard, J; Raleigh, JA; Varia, M; West, C1
Azuma, Y; Chou, SC; Lininger, RA; Murphy, BJ; Raleigh, JA; Varia, MA1
Bennewith, KL; Durand, RE1
Davidson, SE; Harris, AL; Hunter, RD; Hutchison, GJ; Loncaster, JA; Price, PM; Roberts, SA; Stratford, IJ; Valentine, HR; West, CM1
Aquino-Parsons, C; Olive, P; Sobhanifar, S; Stanbridge, EJ1
Aquino-Parsons, C; Banath, JP; Durand, RE; Jankovic, B; MacPhail, SH; Olive, PL; Raleigh, JA; Stanbridge, EJ1
Aquino-Parsons, C; Chou, SC; Davidson, SE; Gebski, V; Havsteen, H; Hunter, R; Lindegaard, JC; Loncaster, J; Nordsmark, M; Overgaard, J; Raleigh, JA; West, C1
Aquino-Parsons, C; Durand, RE1
Calkins, DP; Kennedy, AS; Novotny, DB; Perez, GM; Raleigh, JA; Thrall, DE; Varia, MA1
Ballenger, CA; Calkins-Adams, DP; Fowler, WC; Novotny, DB; Raleigh, JA; Rinker, LH; Varia, MA; Weissler, MC1
Calkins-Adams, DP; Fowler, WC; Kennedy, AS; Novotny, DB; Raleigh, JA; Rinker, LH; Varia, MA1
Ballenger, CA; Calkins-Adams, DP; Chou, SC; Novotny, DB; Raleigh, JA; Varia, MA1
Begg, AC; Geboes, K; Haustermans, K; Hofland, I; Raleigh, J; Van de Pavert, L; Varia, M1
Aquino-Parsons, C; Durand, RE; Luo, C; Olive, PL; Raleigh, JA1
Bono, EL; Chou, SC; Raleigh, JA; Thrall, DE; Varia, MA1
Chou, SC; Davidson, SE; Havsteen, H; Hunter, R; Lindegaard, JC; Loncaster, J; Nordsmark, M; Overgaard, J; Raleigh, JA; Varia, M; West, C1
Aquino-Parsons, C; Lerman, MI; Liao, SY; MacPhail, SH; Olive, PL; Raleigh, JA; Stanbridge, EJ1
Balm, A; Begg, AC; Blommestijn, G; Delaere, P; Hofland, I; Janssen, H; Raleigh, JA; Sciot, R; Sprong, D; Van Velthuyzen, L; Varia, M1
Bennett, MH; Dische, S; Orchard, R; Stratford, MR; Wardman, P1
Bennett, MH; Des Rochers, C; Dische, S; Dunphy, EP; Minchinton, AI; Saunders, MI; Stratford, MR; Wardman, P1

Trials

5 trial(s) available for pimonidazole and Cancer of Cervix

ArticleYear
The prognostic value of pimonidazole and tumour pO2 in human cervix carcinomas after radiation therapy: a prospective international multi-center study.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2006, Volume: 80, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Cell Hypoxia; Female; Humans; Middle Aged; Nitroimidazoles; Oxygen; Partial Pressure; Prognosis; Prospective Studies; Radiation-Sensitizing Agents; Uterine Cervical Neoplasms

2006
The fate of hypoxic (pimonidazole-labelled) cells in human cervix tumours undergoing chemo-radiotherapy.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2006, Volume: 80, Issue:2

    Topics: Adult; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Line, Tumor; Combined Modality Therapy; Female; Humans; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Spheroids, Cellular; Uterine Cervical Neoplasms

2006
A trial of Ro 03-8799 (pimonidazole) in carcinoma of the uterine cervix: an interim report from the Medical Research Council Working Party on advanced carcinoma of the cervix.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1993, Volume: 26, Issue:2

    Topics: Adolescent; Adult; Aged; Blood Transfusion; Brachytherapy; Carcinoma, Squamous Cell; Diarrhea; Female; Follow-Up Studies; Humans; Middle Aged; Neoplasm Recurrence, Local; Nitroimidazoles; Radiation-Sensitizing Agents; Radiotherapy Dosage; Remission Induction; Survival Rate; Uterine Cervical Neoplasms; Vomiting

1993
A clinical study of hypoxia and metallothionein protein expression in squamous cell carcinomas.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:3

    Topics: Biomarkers; Carcinoma, Squamous Cell; Cell Hypoxia; Female; Head and Neck Neoplasms; Humans; Immunohistochemistry; Metallothionein; Neoplasm Staging; Nitroimidazoles; Proliferating Cell Nuclear Antigen; Protein Precursors; Uterine Cervical Neoplasms

2000
Hypoxia and perfusion measurements in human tumors--initial experience with pimonidazole and IUdR.
    Acta oncologica (Stockholm, Sweden), 2001, Volume: 40, Issue:8

    Topics: Antibodies; Biopsy; Diffusion; Esophageal Neoplasms; Female; Head and Neck Neoplasms; Humans; Hypoxia; Idoxuridine; Kinetics; Male; Nitroimidazoles; Nucleic Acid Synthesis Inhibitors; Radiation-Sensitizing Agents; Rectal Neoplasms; Regional Blood Flow; Specimen Handling; Uterine Cervical Neoplasms

2001

Other Studies

24 other study(ies) available for pimonidazole and Cancer of Cervix

ArticleYear
MRI Distinguishes Tumor Hypoxia Levels of Different Prognostic and Biological Significance in Cervical Cancer.
    Cancer research, 2020, 09-15, Volume: 80, Issue:18

    Topics: Algorithms; Animals; Cell Line, Tumor; Chemoradiotherapy; Contrast Media; Epithelial-Mesenchymal Transition; Female; G2 Phase Cell Cycle Checkpoints; Gene Expression Profiling; HeLa Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; M Phase Cell Cycle Checkpoints; Magnetic Resonance Imaging; Mice; Mice, Nude; Neoplasm Transplantation; Nitroimidazoles; Oxidative Phosphorylation; Oxygen Consumption; Prognosis; Treatment Outcome; Tumor Hypoxia; Uterine Cervical Neoplasms

2020
DCE-MRI and Quantitative Histology Reveal Enhanced Vessel Maturation but Impaired Perfusion and Increased Hypoxia in Bevacizumab-Treated Cervical Carcinoma.
    International journal of radiation oncology, biology, physics, 2019, 07-01, Volume: 104, Issue:3

    Topics: Actins; Angiogenesis Inhibitors; Animals; Bevacizumab; Capillary Permeability; Contrast Media; Female; Heterografts; Humans; Magnetic Resonance Imaging; Mice; Mice, Inbred BALB C; Mice, Nude; Microvessels; Nitroimidazoles; Oxygen Consumption; Pericytes; Tumor Hypoxia; Tumor Microenvironment; Uterine Cervical Neoplasms

2019
DCE-MRI of the hypoxic fraction, radioresponsiveness, and metastatic propensity of cervical carcinoma xenografts.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2014, Volume: 110, Issue:2

    Topics: Animals; Cell Hypoxia; Cell Survival; Contrast Media; Female; Gadolinium DTPA; Humans; Lymphatic Metastasis; Magnetic Resonance Imaging; Mice; Mice, Inbred BALB C; Mice, Nude; Nitroimidazoles; Radiation-Sensitizing Agents; Radionuclide Imaging; Uterine Cervical Neoplasms; Xenograft Model Antitumor Assays

2014
Influence of PEG-conjugated hemoglobin on tumor oxygenation and response to chemotherapy.
    Artificial cells, blood substitutes, and immobilization biotechnology, 2008, Volume: 36, Issue:6

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Blood Substitutes; Cisplatin; Drug Synergism; Female; Hemoglobins; Hypoxia; Mice; Mice, Inbred BALB C; Nitroimidazoles; Oxygen Consumption; Polyethylene Glycols; Treatment Outcome; Uterine Cervical Neoplasms; Xenograft Model Antitumor Assays

2008
Inhibition of tumor lactate oxidation: consequences for the tumor microenvironment.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2011, Volume: 99, Issue:3

    Topics: Animals; Autoradiography; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Line, Tumor; Cinnamates; Female; Fluorodeoxyglucose F18; Glucose; Glycolysis; Head and Neck Neoplasms; Immunoenzyme Techniques; Lactates; Linear Models; Luminescent Measurements; Mice; Mice, Nude; Monocarboxylic Acid Transporters; Nitroimidazoles; Oxidation-Reduction; Symporters; Tumor Microenvironment; Uterine Cervical Neoplasms

2011
pO₂ fluctuation pattern and cycling hypoxia in human cervical carcinoma and melanoma xenografts.
    International journal of radiation oncology, biology, physics, 2012, Jul-15, Volume: 83, Issue:4

    Topics: Animals; Cell Hypoxia; Cell Line, Tumor; Coloring Agents; Connective Tissue; Female; Humans; Melanoma; Mice; Mice, Inbred BALB C; Mice, Nude; Microvessels; Nitroimidazoles; Oxygen; Oxygen Consumption; Partial Pressure; Transplantation, Heterologous; Uterine Cervical Neoplasms

2012
Orally administered pimonidazole to label hypoxic tumor cells.
    Cancer research, 2002, Dec-01, Volume: 62, Issue:23

    Topics: Administration, Oral; Animals; Carcinoma, Squamous Cell; Cell Hypoxia; Female; Flow Cytometry; Humans; Male; Mice; Mice, SCID; Neoplasm Transplantation; Nitroimidazoles; Transplantation, Heterologous; Tumor Cells, Cultured; Uterine Cervical Neoplasms

2002
GLUT-1 and CAIX as intrinsic markers of hypoxia in carcinoma of the cervix: relationship to pimonidazole binding.
    International journal of cancer, 2003, Mar-10, Volume: 104, Issue:1

    Topics: Adult; Antigens, Neoplasm; Biomarkers; Biopsy; Carbonic Anhydrase IX; Carbonic Anhydrases; Carcinoma, Squamous Cell; Cell Hypoxia; DNA-Binding Proteins; Energy Metabolism; Female; Gene Expression Regulation, Neoplastic; Glucose Transporter Type 1; Humans; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Microelectrodes; Middle Aged; Monosaccharide Transport Proteins; Neoplasm Proteins; Nitroimidazoles; Nuclear Proteins; Observer Variation; Oxygen; Partial Pressure; Radiation-Sensitizing Agents; Reproducibility of Results; Transcription Factors; Uterine Cervical Neoplasms

2003
Measurements of hypoxia using pimonidazole and polarographic oxygen-sensitive electrodes in human cervix carcinomas.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2003, Volume: 67, Issue:1

    Topics: Adolescent; Adult; Analysis of Variance; Carcinoma; Cell Hypoxia; Computer Graphics; Female; Humans; Microelectrodes; Nitroimidazoles; Oxygen; Polarography; Radiation-Sensitizing Agents; Retrospective Studies; Statistics, Nonparametric; Uterine Cervical Neoplasms

2003
Hypoxia and differentiation in squamous cell carcinomas of the uterine cervix: pimonidazole and involucrin.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, Oct-15, Volume: 9, Issue:13

    Topics: Biopsy; Carcinoma, Squamous Cell; Cell Differentiation; Cell Line, Tumor; Female; Humans; Hypoxia; Immunohistochemistry; In Situ Hybridization; Metallothionein; Nitroimidazoles; Oxygen; Prognosis; Protein Precursors; Radiation-Sensitizing Agents; RNA, Messenger; Transcription, Genetic; Uterine Cervical Neoplasms

2003
Quantifying transient hypoxia in human tumor xenografts by flow cytometry.
    Cancer research, 2004, Sep-01, Volume: 64, Issue:17

    Topics: Adenocarcinoma; Animals; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Line, Tumor; Colonic Neoplasms; Female; Flow Cytometry; Humans; Mice; Mice, SCID; Nitroimidazoles; Oxygen; Partial Pressure; Transplantation, Heterologous; Uterine Cervical Neoplasms

2004
Hypoxia-inducible factor 1alpha expression as an intrinsic marker of hypoxia: correlation with tumor oxygen, pimonidazole measurements, and outcome in locally advanced carcinoma of the cervix.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Dec-15, Volume: 10, Issue:24

    Topics: Antigens, Neoplasm; Biomarkers, Tumor; Carbonic Anhydrase IX; Carbonic Anhydrases; Disease-Free Survival; Female; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Ion-Selective Electrodes; Middle Aged; Neoplasm Recurrence, Local; Nitroimidazoles; Oxygen; Prognosis; Radiation-Sensitizing Agents; Survival Rate; Transcription Factors; Treatment Outcome; Uterine Cervical Neoplasms

2004
Reduced expression of hypoxia-inducible factor-1alpha in perinecrotic regions of solid tumors.
    Cancer research, 2005, Aug-15, Volume: 65, Issue:16

    Topics: Animals; Antigens, Neoplasm; Astrocytoma; Biomarkers, Tumor; Biopsy; Carbonic Anhydrase IX; Carbonic Anhydrases; Cell Hypoxia; Cell Line, Tumor; Colonic Neoplasms; Female; Flow Cytometry; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Image Processing, Computer-Assisted; Mice; Mice, SCID; Necrosis; Neoplasms; Nitroimidazoles; Transcription Factors; Transplantation, Heterologous; Uterine Cervical Neoplasms

2005
Comparison between pimonidazole binding, oxygen electrode measurements, and expression of endogenous hypoxia markers in cancer of the uterine cervix.
    Cytometry. Part B, Clinical cytometry, 2006, Volume: 70, Issue:2

    Topics: Antigens, Neoplasm; Biomarkers, Tumor; Biopsy; Carbonic Anhydrase IX; Carbonic Anhydrases; Cell Hypoxia; Cervix Uteri; DNA, Neoplasm; Electrodes; Female; Flow Cytometry; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Middle Aged; Nitroimidazoles; Oxygen; Phenotype; Predictive Value of Tests; Prognosis; S Phase; Time Factors; Uterine Cervical Neoplasms

2006
Proliferation and hypoxia in human squamous cell carcinoma of the cervix: first report of combined immunohistochemical assays.
    International journal of radiation oncology, biology, physics, 1997, Mar-01, Volume: 37, Issue:4

    Topics: Adult; Antigens, Nuclear; Biomarkers; Carcinoma, Squamous Cell; Cell Division; Cell Hypoxia; Female; Humans; Immunohistochemistry; Ki-67 Antigen; Nitroimidazoles; Nuclear Proteins; Proliferating Cell Nuclear Antigen; Radiation-Sensitizing Agents; Uterine Cervical Neoplasms

1997
Hypoxia and vascular endothelial growth factor expression in human squamous cell carcinomas using pimonidazole as a hypoxia marker.
    Cancer research, 1998, Sep-01, Volume: 58, Issue:17

    Topics: Biomarkers; Carcinoma, Squamous Cell; Cell Hypoxia; Endothelial Growth Factors; Female; Head and Neck Neoplasms; Humans; Immunohistochemistry; Lymphokines; Nitroimidazoles; Uterine Cervical Neoplasms; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

1998
Pimonidazole: a novel hypoxia marker for complementary study of tumor hypoxia and cell proliferation in cervical carcinoma.
    Gynecologic oncology, 1998, Volume: 71, Issue:2

    Topics: Biomarkers; Cell Division; Cell Hypoxia; Female; Humans; Immunohistochemistry; Nitroimidazoles; Proliferating Cell Nuclear Antigen; S Phase; Uterine Cervical Neoplasms

1998
Diffusion limited hypoxia estimated by vascular image analysis: comparison with pimonidazole staining in human tumors.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2000, Volume: 55, Issue:3

    Topics: Adenocarcinoma; Blood Vessels; Carcinoma, Squamous Cell; Cell Hypoxia; Diffusion; Esophageal Neoplasms; Female; Humans; Image Processing, Computer-Assisted; Nitroimidazoles; Observer Variation; Radiation-Sensitizing Agents; Rectal Neoplasms; Reproducibility of Results; Uterine Cervical Neoplasms

2000
Comparison between the comet assay and pimonidazole binding for measuring tumour hypoxia.
    British journal of cancer, 2000, Volume: 83, Issue:11

    Topics: Animals; Antibodies, Monoclonal; Carcinoma, Squamous Cell; Cell Hypoxia; Comet Assay; Cricetinae; Cricetulus; DNA, Neoplasm; Female; Flow Cytometry; Fluorescein-5-isothiocyanate; Humans; Immunoconjugates; Male; Mice; Mice, Inbred C3H; Mice, Inbred NOD; Mice, SCID; Nitroimidazoles; Radiation-Sensitizing Agents; Uterine Cervical Neoplasms; Xenograft Model Antitumor Assays

2000
Semiquantitative immunohistochemical analysis for hypoxia in human tumors.
    International journal of radiation oncology, biology, physics, 2001, Feb-01, Volume: 49, Issue:2

    Topics: Calibration; Carcinoma, Squamous Cell; Cell Hypoxia; Female; Head and Neck Neoplasms; Humans; Immunohistochemistry; Nitroimidazoles; Observer Variation; Radiation-Sensitizing Agents; Uterine Cervical Neoplasms

2001
Invasive oxygen measurements and pimonidazole labeling in human cervix carcinoma.
    International journal of radiation oncology, biology, physics, 2001, Feb-01, Volume: 49, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Carcinoma; Cell Hypoxia; Female; Humans; Middle Aged; Nitroimidazoles; Oxygen; Partial Pressure; Radiation-Sensitizing Agents; Uterine Cervical Neoplasms

2001
Carbonic anhydrase 9 as an endogenous marker for hypoxic cells in cervical cancer.
    Cancer research, 2001, Dec-15, Volume: 61, Issue:24

    Topics: Animals; Antigens, Neoplasm; Biomarkers, Tumor; Carbonic Anhydrase IX; Carbonic Anhydrases; Cell Hypoxia; Female; Glioma; Humans; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasm Proteins; Neoplasm Transplantation; Nitroimidazoles; Oxygen; Radiation Tolerance; Radiation-Sensitizing Agents; Transplantation, Heterologous; Uterine Cervical Neoplasms

2001
The uptake of the radiosensitizing compound Ro 03-8799 (Pimonidazole) in human tumors.
    International journal of radiation oncology, biology, physics, 1989, Volume: 16, Issue:4

    Topics: Breast Neoplasms; Female; Humans; Melanoma; Neoplasms; Nitroimidazoles; Radiation-Sensitizing Agents; Rectal Neoplasms; Uterine Cervical Neoplasms

1989
A comparison of the tumour concentrations obtainable with misonidazole and Ro 03-8799.
    The British journal of radiology, 1986, Volume: 59, Issue:705

    Topics: Adult; Aged; Animals; Carcinoma, Squamous Cell; Cricetinae; Cricetulus; Female; Humans; Male; Melanoma; Mice; Middle Aged; Misonidazole; Nitroimidazoles; Radiation-Sensitizing Agents; Uterine Cervical Neoplasms

1986