pimobendan has been researched along with Myocardial Ischemia in 5 studies
pimobendan: produces arterial & venous dilatation in dogs; structure given in first source
Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
| Excerpt | Relevance | Reference |
|---|---|---|
| "In contrast to cyclic AMP-dependent positive inotropes, the calcium-sensitizer and partial phosphodiesterase (PDE) inhibitor pimobendan may induce beneficial effects in heart failure." | 9.07 | Hemodynamic, neurohumoral, and myocardial energetic effects of pimobendan, a novel calcium-sensitizing compound, in patients with mild to moderate heart failure. ( Bartels, GL; de Leeuw, PW; Krauss, XH; Kruijssen, DA; Remme, WJ; Storm, CJ; van Hoogenhuyze, DC, 1994) |
| "In contrast to cyclic AMP-dependent positive inotropes, the calcium-sensitizer and partial phosphodiesterase (PDE) inhibitor pimobendan may induce beneficial effects in heart failure." | 5.07 | Hemodynamic, neurohumoral, and myocardial energetic effects of pimobendan, a novel calcium-sensitizing compound, in patients with mild to moderate heart failure. ( Bartels, GL; de Leeuw, PW; Krauss, XH; Kruijssen, DA; Remme, WJ; Storm, CJ; van Hoogenhuyze, DC, 1994) |
| "Pimobendan is a drug with positive inotropic effects that additionally inhibits the production of proinflammatory cytokines." | 2.42 | The role of Ca++-sensitizers for the treatment of heart failure. ( Boldt, J; Kirchner, J; Lehmann, A, 2003) |
| "Pretreatment with rolipram decreased the duration of ventricular tachycardia without any change in the incidences of dysrhythmias or the mortality rate." | 1.32 | Effects of rolipram, pimobendan and zaprinast on ischaemia-induced dysrhythmias and on ventricular cyclic nucleotide content in the anaesthetized rat. ( Aleixandre, F; Carceles, MD; Fuente, T; Laorden, ML; López-Vidal, J, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Carceles, MD | 1 |
| Aleixandre, F | 1 |
| Fuente, T | 1 |
| López-Vidal, J | 1 |
| Laorden, ML | 1 |
| Lehmann, A | 1 |
| Boldt, J | 1 |
| Kirchner, J | 1 |
| Hagemeijer, F | 1 |
| Remme, WJ | 1 |
| Kruijssen, DA | 1 |
| van Hoogenhuyze, DC | 1 |
| Krauss, XH | 1 |
| Bartels, GL | 1 |
| Storm, CJ | 1 |
| de Leeuw, PW | 1 |
| Abe, Y | 1 |
| Sekioka, K | 1 |
| Ishisu, R | 1 |
| Onishi, K | 1 |
| Ueda, Y | 1 |
| Nakano, T | 1 |
1 review available for pimobendan and Myocardial Ischemia
| Article | Year |
|---|---|
The role of Ca++-sensitizers for the treatment of heart failure.
Topics: Calcium; Cardiotonic Agents; Chronic Disease; Clinical Trials as Topic; Dobutamine; Heart Failure; H | 2003 |
1 trial available for pimobendan and Myocardial Ischemia
| Article | Year |
|---|---|
Hemodynamic, neurohumoral, and myocardial energetic effects of pimobendan, a novel calcium-sensitizing compound, in patients with mild to moderate heart failure.
Topics: Adult; Aged; Blood Pressure; Cardiac Output; Cardiotonic Agents; Catecholamines; Coronary Angiograph | 1994 |
3 other studies available for pimobendan and Myocardial Ischemia
| Article | Year |
|---|---|
Effects of rolipram, pimobendan and zaprinast on ischaemia-induced dysrhythmias and on ventricular cyclic nucleotide content in the anaesthetized rat.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Anesthesia; Animals; Arrhy | 2003 |
Hemodynamic performance during exercise in patients with severe chronic congestive heart failure before and after a single dose of pimobendan.
Topics: Administration, Oral; Aged; Cardiomyopathy, Dilated; Cardiotonic Agents; Child; Exercise; Female; He | 1994 |
Restoration of ischemic contractile failure of indo-1-loaded guinea pig heart by a calcium sensitizer, MCI-154.
Topics: Animals; Calcium; Cardiotonic Agents; Guinea Pigs; Indoles; Male; Myocardial Contraction; Myocardial | 1996 |