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pimobendan and Hypertension, Pulmonary

pimobendan has been researched along with Hypertension, Pulmonary in 6 studies

pimobendan: produces arterial & venous dilatation in dogs; structure given in first source

Hypertension, Pulmonary: Increased VASCULAR RESISTANCE in the PULMONARY CIRCULATION, usually secondary to HEART DISEASES or LUNG DISEASES.

Research Excerpts

ExcerptRelevanceReference
" Echocardiography results and invasive measurements of right and left ventricular systolic pressures were compared after 3-week administrations of sildenafil (S group), pimobendan (P group), nicorandil (N group), and their combinations (SP and SPN groups) in male rats with monocrotaline (MCT)-induced pulmonary hypertension (M group) and without this condition (C group)."7.81Effects of Single Drug and Combined Short-term Administration of Sildenafil, Pimobendan, and Nicorandil on Right Ventricular Function in Rats With Monocrotaline-induced Pulmonary Hypertension. ( Fukayama, T; Fukushima, R; Goya, S; Nakata, TM; Tanaka, R; Yoshiyuki, R, 2015)
"Pimobendan is a positive inotropic agent that dilates blood vessels and sensitizes the myocardium to calcium."6.68[Effects of pimobendan on pulmonary hypertension in patients with chronic pulmonary emphysema]. ( Fujikane, T; Matsumoto, H; Sasaki, N; Shimizu, T; Takahashi, M; Takahashi, T; Takeda, A; Tsuji, T; Yamazaki, Y, 1997)
"Pimobendan is an inotropic drug with phosphodiesterase 3 inhibitory and calcium-sensitizing effects."5.56Acute effects of intravenous pimobendan administration in dog models of chronic precapillary pulmonary hypertension. ( Kawamoto, S; Miki, S; Morita, T; Nakamura, K; Osuga, T; Sasaoka, K; Takiguchi, M, 2020)
" Echocardiography results and invasive measurements of right and left ventricular systolic pressures were compared after 3-week administrations of sildenafil (S group), pimobendan (P group), nicorandil (N group), and their combinations (SP and SPN groups) in male rats with monocrotaline (MCT)-induced pulmonary hypertension (M group) and without this condition (C group)."3.81Effects of Single Drug and Combined Short-term Administration of Sildenafil, Pimobendan, and Nicorandil on Right Ventricular Function in Rats With Monocrotaline-induced Pulmonary Hypertension. ( Fukayama, T; Fukushima, R; Goya, S; Nakata, TM; Tanaka, R; Yoshiyuki, R, 2015)
"Pimobendan is a positive inotropic agent that dilates blood vessels and sensitizes the myocardium to calcium."2.68[Effects of pimobendan on pulmonary hypertension in patients with chronic pulmonary emphysema]. ( Fujikane, T; Matsumoto, H; Sasaki, N; Shimizu, T; Takahashi, M; Takahashi, T; Takeda, A; Tsuji, T; Yamazaki, Y, 1997)
"Pimobendan is an inotropic drug with phosphodiesterase 3 inhibitory and calcium-sensitizing effects."1.56Acute effects of intravenous pimobendan administration in dog models of chronic precapillary pulmonary hypertension. ( Kawamoto, S; Miki, S; Morita, T; Nakamura, K; Osuga, T; Sasaoka, K; Takiguchi, M, 2020)
"In dogs with canine monocytic ehrlichiosis (CME), respiratory signs are uncommon and clinical and radiographic signs of interstitial pneumonia are poorly described."1.43Interstitial pneumonia and pulmonary hypertension associated with suspected ehrlichiosis in a dog. ( Broens, EM; Dobak, TP; Toom, ML; Valtolina, C, 2016)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's2 (33.33)29.6817
2010's2 (33.33)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Morita, T2
Nakamura, K1
Osuga, T1
Kawamoto, S1
Miki, S1
Sasaoka, K1
Takiguchi, M1
Nakata, TM1
Tanaka, R1
Yoshiyuki, R1
Fukayama, T1
Goya, S1
Fukushima, R1
Toom, ML1
Dobak, TP1
Broens, EM1
Valtolina, C1
Watanabe, E1
Shiga, T1
Matsuda, N1
Kajimoto, K1
Naganuma, M1
Kawai, A1
Kasanuki, H1
Sahara, M1
Takahashi, T2
Imai, Y1
Nakajima, T1
Yao, A1
Hirata, Y1
Nagai, R1
Yamazaki, Y1
Matsumoto, H1
Takeda, A1
Sasaki, N1
Takahashi, M1
Tsuji, T1
Fujikane, T1
Shimizu, T1

Reviews

1 review available for pimobendan and Hypertension, Pulmonary

ArticleYear
New insights in the treatment strategy for pulmonary arterial hypertension.
    Cardiovascular drugs and therapy, 2006, Volume: 20, Issue:5

    Topics: Anticoagulants; Antihypertensive Agents; Calcium Channel Blockers; Diuretics; Drug Therapy, Combinat

2006

Trials

1 trial available for pimobendan and Hypertension, Pulmonary

ArticleYear
[Effects of pimobendan on pulmonary hypertension in patients with chronic pulmonary emphysema].
    Nihon Kyobu Shikkan Gakkai zasshi, 1997, Volume: 35, Issue:8

    Topics: Aged; Blood Pressure; Cardiac Output; Chronic Disease; Humans; Hypertension, Pulmonary; Male; Middle

1997

Other Studies

4 other studies available for pimobendan and Hypertension, Pulmonary

ArticleYear
Acute effects of intravenous pimobendan administration in dog models of chronic precapillary pulmonary hypertension.
    Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology, 2020, Volume: 32

    Topics: Animals; Cardiotonic Agents; Dog Diseases; Dogs; Echocardiography; Hypertension, Pulmonary; Infusion

2020
Effects of Single Drug and Combined Short-term Administration of Sildenafil, Pimobendan, and Nicorandil on Right Ventricular Function in Rats With Monocrotaline-induced Pulmonary Hypertension.
    Journal of cardiovascular pharmacology, 2015, Volume: 65, Issue:6

    Topics: Animals; Disease Models, Animal; Drug Therapy, Combination; Hemodynamics; Hypertension, Pulmonary; H

2015
Interstitial pneumonia and pulmonary hypertension associated with suspected ehrlichiosis in a dog.
    Acta veterinaria Scandinavica, 2016, Jul-07, Volume: 58, Issue:1

    Topics: Animals; Antiparasitic Agents; Dog Diseases; Dogs; Doxycycline; Ehrlichiosis; Heart Failure; Hyperte

2016
Low-dose systemic phosphodiesterase III inhibitor pimobendan combined with prostacyclin therapy in a patient with severe primary pulmonary hypertension.
    Cardiovascular drugs and therapy, 2003, Volume: 17, Issue:4

    Topics: Adult; Drug Therapy, Combination; Epoprostenol; Female; Heart Failure; Humans; Hypertension, Pulmona

2003