pimobendan has been researched along with Coronary Disease in 6 studies
pimobendan: produces arterial & venous dilatation in dogs; structure given in first source
Coronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of MCI-154, a cardiotonic agent with Ca++ sensitizing actions, on the ischemic contractile failure and myocardial acidosis were studied in the dog heart, in which the left anterior descending coronary artery (LAD) was partially occluded for 90 min, and compared with those of dobutamine, milrinone, pimobendan and isosorbide dinitrate (ISDN)." | 7.68 | Beneficial effect of MCI-154, a cardiotonic agent, on ischemic contractile failure and myocardial acidosis of dog hearts: comparison with dobutamine, milrinone and pimobendan. ( Abe, Y; Kitada, Y; Narimatsu, A, 1992) |
| "Pimobendan (UD-CG 115 BS) was administered orally to 23 patients with congestive heart failure (functional class IV) caused by coronary artery disease (11 patients) or idiopathic dilated cardiomyopathy (12)." | 7.67 | Hemodynamic effects of pimobendan given orally in congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy. ( Brand, HJ; Hagemeijer, F; van Mechelen, R, 1989) |
| "The effects of MCI-154, a cardiotonic agent with Ca++ sensitizing actions, on the ischemic contractile failure and myocardial acidosis were studied in the dog heart, in which the left anterior descending coronary artery (LAD) was partially occluded for 90 min, and compared with those of dobutamine, milrinone, pimobendan and isosorbide dinitrate (ISDN)." | 3.68 | Beneficial effect of MCI-154, a cardiotonic agent, on ischemic contractile failure and myocardial acidosis of dog hearts: comparison with dobutamine, milrinone and pimobendan. ( Abe, Y; Kitada, Y; Narimatsu, A, 1992) |
| "Pimobendan (UD-CG 115 BS) was administered orally to 23 patients with congestive heart failure (functional class IV) caused by coronary artery disease (11 patients) or idiopathic dilated cardiomyopathy (12)." | 3.67 | Hemodynamic effects of pimobendan given orally in congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy. ( Brand, HJ; Hagemeijer, F; van Mechelen, R, 1989) |
| "In pimobendan treated patients and volunteers an increase in forearm blood flow between 9% and 38% could be noticed." | 2.66 | [Effect of pimobendan on peripheral hemodynamics]. ( Kothe, A; Peters, P; Saborowski, F, 1989) |
| "Pimobendan (UD-CG 115) is a long-acting positive inotropic drug with arterio- and venodilator properties." | 1.27 | Effects of pimobendan (UD-CG 115) on the contractile function of the normal and "postischemic" canine myocardium. ( Balasim, H; Charlier, AA; Gurné, O; Hanet, C; Pouleur, H; Van Mechelen, H, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (83.33) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abe, Y | 1 |
| Kitada, Y | 1 |
| Narimatsu, A | 1 |
| Pouleur, H | 1 |
| Gurné, O | 1 |
| Hanet, C | 1 |
| Balasim, H | 1 |
| Van Mechelen, H | 1 |
| Charlier, AA | 1 |
| Permanetter, B | 1 |
| Baumann, G | 1 |
| Wirtzfeld, A | 1 |
| Günes, S | 1 |
| Stinshoff, M | 1 |
| Klein, G | 1 |
| Peters, P | 1 |
| Saborowski, F | 1 |
| Kothe, A | 1 |
| Verdouw, PD | 1 |
| Hartog, JM | 1 |
| Duncker, DJ | 1 |
| Roth, W | 1 |
| Saxena, PR | 1 |
| Hagemeijer, F | 1 |
| Brand, HJ | 1 |
| van Mechelen, R | 1 |
2 trials available for pimobendan and Coronary Disease
| Article | Year |
|---|---|
[Acute and chronic effects of UDCG 115 BS (pimobendan) in patients with advanced myocardial failure].
Topics: Adult; Aged; Cardiac Output; Cardiomyopathy, Dilated; Cardiotonic Agents; Clinical Trials as Topic; | 1989 |
[Effect of pimobendan on peripheral hemodynamics].
Topics: Adult; Blood Pressure; Coronary Disease; Double-Blind Method; Exercise Test; Forearm; Heart Rate; He | 1989 |
4 other studies available for pimobendan and Coronary Disease
| Article | Year |
|---|---|
Beneficial effect of MCI-154, a cardiotonic agent, on ischemic contractile failure and myocardial acidosis of dog hearts: comparison with dobutamine, milrinone and pimobendan.
Topics: Acidosis; Animals; Cardiotonic Agents; Coronary Disease; Dobutamine; Dogs; Female; Hemodynamics; Hyd | 1992 |
Effects of pimobendan (UD-CG 115) on the contractile function of the normal and "postischemic" canine myocardium.
Topics: Animals; Cardiotonic Agents; Coronary Circulation; Coronary Disease; Dogs; Muscles; Myocardial Contr | 1988 |
Cardiovascular profile of pimobendan, a benzimidazole-pyridazinone derivative with vasodilating and inotropic properties.
Topics: Adrenergic beta-Antagonists; Animals; Cardiac Output; Cardiotonic Agents; Coronary Circulation; Coro | 1986 |
Hemodynamic effects of pimobendan given orally in congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy.
Topics: Administration, Oral; Aged; Cardiomyopathy, Dilated; Coronary Disease; Female; Heart Failure; Hemody | 1989 |