pimobendan has been researched along with Acidosis in 3 studies
pimobendan: produces arterial & venous dilatation in dogs; structure given in first source
Acidosis: A pathologic condition of acid accumulation or depletion of base in the body. The two main types are RESPIRATORY ACIDOSIS and metabolic acidosis, due to metabolic acid build up.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of MCI-154, a cardiotonic agent with Ca++ sensitizing actions, on the ischemic contractile failure and myocardial acidosis were studied in the dog heart, in which the left anterior descending coronary artery (LAD) was partially occluded for 90 min, and compared with those of dobutamine, milrinone, pimobendan and isosorbide dinitrate (ISDN)." | 7.68 | Beneficial effect of MCI-154, a cardiotonic agent, on ischemic contractile failure and myocardial acidosis of dog hearts: comparison with dobutamine, milrinone and pimobendan. ( Abe, Y; Kitada, Y; Narimatsu, A, 1992) |
| "We studied the influence of acidosis on the positive inotropic effect of UD-CG 212 Cl (4,5-dihydro-6-[2-(4-hydroxyphenyl)-1H-benzimidazole-5-yl]-5-methyl-3(2H)-pyridazinone), an active metabolite of pimobendan, in canine ventricular trabeculae loaded with aequorin." | 3.71 | Decrease in Ca(2+)-sensitizing effect of UD-CG 212 Cl, a metabolite of pimobendan, under acidotic condition in canine ventricular myocardium. ( Endoh, M; Shimazaki, Y; Takahashi, R, 2001) |
| "The effects of MCI-154, a cardiotonic agent with Ca++ sensitizing actions, on the ischemic contractile failure and myocardial acidosis were studied in the dog heart, in which the left anterior descending coronary artery (LAD) was partially occluded for 90 min, and compared with those of dobutamine, milrinone, pimobendan and isosorbide dinitrate (ISDN)." | 3.68 | Beneficial effect of MCI-154, a cardiotonic agent, on ischemic contractile failure and myocardial acidosis of dog hearts: comparison with dobutamine, milrinone and pimobendan. ( Abe, Y; Kitada, Y; Narimatsu, A, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Takahashi, R | 1 |
| Shimazaki, Y | 1 |
| Endoh, M | 1 |
| Abe, Y | 2 |
| Kitada, Y | 2 |
| Narimatsu, A | 2 |
| Tobe, A | 1 |
3 other studies available for pimobendan and Acidosis
| Article | Year |
|---|---|
Decrease in Ca(2+)-sensitizing effect of UD-CG 212 Cl, a metabolite of pimobendan, under acidotic condition in canine ventricular myocardium.
Topics: Acidosis; Actin Cytoskeleton; Aequorin; Animals; Calcium; Cardiotonic Agents; Dogs; Female; Heart; H | 2001 |
Beneficial effect of MCI-154, a cardiotonic agent, on ischemic contractile failure and myocardial acidosis of dog hearts: comparison with dobutamine, milrinone and pimobendan.
Topics: Acidosis; Animals; Cardiotonic Agents; Coronary Disease; Dobutamine; Dogs; Female; Hemodynamics; Hyd | 1992 |
MCI-154, a novel cardiotonic agent, reverses the acidic pH-induced decrease in responses of cardiac myofilaments to Ca++: comparison with sulmazole and pimobendan.
Topics: Acidosis; Actin Cytoskeleton; Animals; Calcium; Cardiotonic Agents; Guinea Pigs; Hydrogen-Ion Concen | 1991 |