pimagedine has been researched along with Subarachnoid Hemorrhage in 3 studies
pimagedine: diamine oxidase & nitric oxide synthase inhibitor; an advanced glycosylation end product inhibitor; used in the treatment of diabetic complications; structure
aminoguanidine : A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.
Subarachnoid Hemorrhage: Bleeding into the intracranial or spinal SUBARACHNOID SPACE, most resulting from INTRACRANIAL ANEURYSM rupture. It can occur after traumatic injuries (SUBARACHNOID HEMORRHAGE, TRAUMATIC). Clinical features include HEADACHE; NAUSEA; VOMITING, nuchal rigidity, variable neurological deficits and reduced mental status.
| Excerpt | Relevance | Reference |
|---|---|---|
| " An intravenous bolus injection of AG (150 mg/kg) was administrated 1h after SAH, and this dosage was repeated on the following day." | 1.36 | Aminoguanidine inhibition of iNOS activity ameliorates cerebral vasospasm after subarachnoid hemorrhage in rabbits via restoration of dysfunctional endothelial cells. ( Chen, X; Shi, C; Wang, L; Zhao, S; Zheng, B; Zheng, T, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zheng, B | 1 |
| Zheng, T | 1 |
| Wang, L | 1 |
| Chen, X | 1 |
| Shi, C | 1 |
| Zhao, S | 1 |
| Kwan, AL | 1 |
| Solenski, NJ | 1 |
| Kassell, NF | 1 |
| Lee, KS | 1 |
| Sayama, T | 1 |
| Suzuki, S | 1 |
| Fukui, M | 1 |
3 other studies available for pimagedine and Subarachnoid Hemorrhage
| Article | Year |
|---|---|
Aminoguanidine inhibition of iNOS activity ameliorates cerebral vasospasm after subarachnoid hemorrhage in rabbits via restoration of dysfunctional endothelial cells.
Topics: Analysis of Variance; Animals; Basilar Artery; Cerebral Angiography; Disease Models, Animal; Endothe | 2010 |
Inhibition of nitric oxide generation and lipid peroxidation attenuates hemolysate-induced injury to cerebrovascular endothelium.
Topics: Animals; Antioxidants; Brain; Cattle; Cell Membrane Permeability; Cells, Cultured; Endothelium, Vasc | 1997 |
Role of inducible nitric oxide synthase in the cerebral vasospasm after subarachnoid hemorrhage in rats.
Topics: Animals; Antibodies; Cerebral Arteries; Cerebrovascular Circulation; DNA Probes; Endothelium, Vascul | 1999 |