pimagedine has been researched along with Stomach Ulcer in 8 studies
pimagedine: diamine oxidase & nitric oxide synthase inhibitor; an advanced glycosylation end product inhibitor; used in the treatment of diabetic complications; structure
aminoguanidine : A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.
Stomach Ulcer: Ulceration of the GASTRIC MUCOSA due to contact with GASTRIC JUICE. It is often associated with HELICOBACTER PYLORI infection or consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).
| Excerpt | Relevance | Reference |
|---|---|---|
| "After gastric ulcers were induced by acetic acid, rats were treated with vehicle, N(G)-nitro-L-arginine methyl ester (L-NAME), aminoguanidine (AG), and dexamethasone (Dex) by gastric intubation twice a day for 3 days to 1 week." | 1.30 | Inhibition of inducible nitric oxide synthase delays gastric ulcer healing in the rat. ( Akiba, Y; Ishii, H; Kimura, H; Miura, S; Mori, M; Nakamura, M; Oda, M; Suzuki, H; Tsuchiya, M, 1998) |
| " The inhibition was characterized by displacement of the dose-response to histamine to the right, in parallel, without depression of the maximum." | 1.27 | Actions of nizatidine on the rat uterus, dog stomach and experimentally induced gastric lesions. ( Evans, DC; Lin, TM; Ruffolo, RR; Warrick, MW, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kato, S | 2 |
| Kawahara, R | 1 |
| Yasuda, M | 1 |
| Amagase, K | 1 |
| Takeuchi, K | 3 |
| Nagai, N | 1 |
| Takeda, A | 1 |
| Itanami, Y | 1 |
| Ito, Y | 1 |
| West, SD | 1 |
| Helmer, KS | 1 |
| Chang, LK | 1 |
| Cui, Y | 1 |
| Greeley, GH | 1 |
| Mercer, DW | 1 |
| Araki, H | 1 |
| Komoike, Y | 1 |
| Matsumoto, M | 1 |
| Tanaka, A | 1 |
| Takehara, K | 1 |
| Asada, Y | 1 |
| Yasuiro, T | 1 |
| Nishida, K | 1 |
| Ohta, Y | 1 |
| Ishiguro, I | 1 |
| Akiba, Y | 1 |
| Nakamura, M | 1 |
| Mori, M | 1 |
| Suzuki, H | 1 |
| Oda, M | 1 |
| Kimura, H | 1 |
| Miura, S | 1 |
| Tsuchiya, M | 1 |
| Ishii, H | 1 |
| Lin, TM | 1 |
| Evans, DC | 1 |
| Warrick, MW | 1 |
| Ruffolo, RR | 1 |
8 other studies available for pimagedine and Stomach Ulcer
| Article | Year |
|---|---|
Aggravation of cold-restraint stress-induced gastric lesions in adjuvant arthritic rats: pathogenic role of inducible and endothelial nitric oxide.
Topics: Animals; Arthritis, Experimental; Blotting, Western; Cold Temperature; Enzyme Inhibitors; Gastric Mu | 2009 |
Co-administration of water containing magnesium ion prevents loxoprofen-induced lesions in gastric mucosa of adjuvant-induced arthritis rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arthritis, Experimental; Drug T | 2012 |
Cholecystokinin secretagogue-induced gastroprotection: role of nitric oxide and blood flow.
Topics: Acids; Animals; Blotting, Western; Cholecystokinin; Enzyme Inhibitors; Ethanol; Female; Gastric Muco | 2003 |
Healing of duodenal ulcers is not impaired by indomethacin or rofecoxib, the selective COX-2 inhibitor, in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Duodenal Ulcer; Enzyme | 2002 |
Role of nitric oxide in mucosal blood flow response and the healing of HCl-induced lesions in the rat stomach.
Topics: Animals; Blood Flow Velocity; Cell Membrane Permeability; Enzyme Inhibitors; Gastric Acid; Gastric M | 1997 |
Role of gastric mucosal constitutive and inducible nitric oxide synthases in the development of stress-induced gastric mucosal lesions in rats.
Topics: Animals; Enzyme Inhibitors; Gastric Mucosa; Guanidines; Immersion; Male; Nitric Oxide Synthase; omeg | 1997 |
Inhibition of inducible nitric oxide synthase delays gastric ulcer healing in the rat.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Dexamethasone; Enzyme Inhibitors; Fluorescent Antibody | 1998 |
Actions of nizatidine on the rat uterus, dog stomach and experimentally induced gastric lesions.
Topics: Animals; Aspirin; Atropine; Dogs; Duodenum; Female; Gastrointestinal Motility; Guanidines; Guinea Pi | 1986 |