pimagedine has been researched along with Status Epilepticus in 2 studies
pimagedine: diamine oxidase & nitric oxide synthase inhibitor; an advanced glycosylation end product inhibitor; used in the treatment of diabetic complications; structure
aminoguanidine : A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.
Status Epilepticus: A prolonged seizure or seizures repeated frequently enough to prevent recovery between episodes occurring over a period of 20-30 minutes. The most common subtype is generalized tonic-clonic status epilepticus, a potentially fatal condition associated with neuronal injury and respiratory and metabolic dysfunction. Nonconvulsive forms include petit mal status and complex partial status, which may manifest as behavioral disturbances. Simple partial status epilepticus consists of persistent motor, sensory, or autonomic seizures that do not impair cognition (see also EPILEPSIA PARTIALIS CONTINUA). Subclinical status epilepticus generally refers to seizures occurring in an unresponsive or comatose individual in the absence of overt signs of seizure activity. (From N Engl J Med 1998 Apr 2;338(14):970-6; Neurologia 1997 Dec;12 Suppl 6:25-30)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Severity of kindled seizures was assessed in terms of a composite kindled seizure severity score (KSSS)." | 1.35 | Pharmacological inhibition of inducible nitric oxide synthase attenuates the development of seizures in mice. ( Kalra, R; Rehni, AK; Singh, N; Singh, TG, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rehni, AK | 1 |
| Singh, TG | 1 |
| Kalra, R | 1 |
| Singh, N | 1 |
| Liu, ZW | 1 |
| Zhang, T | 1 |
| Yang, Z | 1 |
2 other studies available for pimagedine and Status Epilepticus
| Article | Year |
|---|---|
Pharmacological inhibition of inducible nitric oxide synthase attenuates the development of seizures in mice.
Topics: Analysis of Variance; Animals; Convulsants; Guanidines; Male; Mice; Nitric Oxide Synthase Type II; P | 2009 |
Involvement of nitric oxide in spatial memory deficits in status epilepticus rats.
Topics: Animals; Glutathione Peroxidase; Guanidines; Hippocampus; Indazoles; Male; Malondialdehyde; Maze Lea | 2007 |