pimagedine has been researched along with Renal Insufficiency in 3 studies
pimagedine: diamine oxidase & nitric oxide synthase inhibitor; an advanced glycosylation end product inhibitor; used in the treatment of diabetic complications; structure
aminoguanidine : A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.
Renal Insufficiency: Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal insufficiency can be classified by the degree of kidney damage (as measured by the level of PROTEINURIA) and reduction in GLOMERULAR FILTRATION RATE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "AGEs accumulate in renal failure as a result of decreased excretion and increased generation resulting from oxidative and carbonyl stress of uremia." | 2.41 | Advanced glycation end products: a Nephrologist's perspective. ( Choudhury, D; Levi, M; Raj, DS; Welbourne, TC, 2000) |
| "Our aim was to evaluate NO role in renal failure induced during decompensated cirrhosis, using the following inhibitors: aminoguanidine (AG), a specific inducible nitric oxide synthase (iNOS) inhibitor and NG-nitro-l-arginine methyl ester (L-NAME), a nonselective blocker of NOS isoforms." | 1.33 | Nitric oxide synthases inhibition results in renal failure improvement in cirrhotic rats. ( Alvarez-Rodríguez, A; Armendáriz-Borunda, J; Covarrubias, A; Grijalva, G; Islas-Carbajal, MC; Rincón-Sánchez, AR, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Islas-Carbajal, MC | 1 |
| Covarrubias, A | 1 |
| Grijalva, G | 1 |
| Alvarez-Rodríguez, A | 1 |
| Armendáriz-Borunda, J | 1 |
| Rincón-Sánchez, AR | 1 |
| Monnier, V | 1 |
| Raj, DS | 1 |
| Choudhury, D | 1 |
| Welbourne, TC | 1 |
| Levi, M | 1 |
2 reviews available for pimagedine and Renal Insufficiency
| Article | Year |
|---|---|
[Non-enzymatic glycosylation of proteins. Complications of diabetes mellitus, aging and kidney failure].
Topics: Aging; Arginine; Blood Glucose; Diabetes Mellitus; Diabetic Neuropathies; Glycation End Products, Ad | 1993 |
Advanced glycation end products: a Nephrologist's perspective.
Topics: Aging; Arteriosclerosis; Cross-Linking Reagents; Diabetes Complications; Glycation End Products, Adv | 2000 |
1 other study available for pimagedine and Renal Insufficiency
| Article | Year |
|---|---|
Nitric oxide synthases inhibition results in renal failure improvement in cirrhotic rats.
Topics: Animals; Aspartate Aminotransferases; Creatinine; Disease Models, Animal; Enzyme Inhibitors; Guanidi | 2005 |