pimagedine has been researched along with Pulmonary Fibrosis in 8 studies
pimagedine: diamine oxidase & nitric oxide synthase inhibitor; an advanced glycosylation end product inhibitor; used in the treatment of diabetic complications; structure
aminoguanidine : A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.
Pulmonary Fibrosis: A process in which normal lung tissues are progressively replaced by FIBROBLASTS and COLLAGEN causing an irreversible loss of the ability to transfer oxygen into the bloodstream via PULMONARY ALVEOLI. Patients show progressive DYSPNEA finally resulting in death.
| Excerpt | Relevance | Reference |
|---|---|---|
| " AGEs level in lung tissue was determined by ELISA and pulmonary fibrosis was evaluated by Ashcroft score and hydroxyproline assay." | 3.75 | Blockade of advanced glycation end product formation attenuates bleomycin-induced pulmonary fibrosis in rats. ( Chen, L; Chen, YJ; Li, JQ; Liu, DS; Liu, L; Sun, BB; Wang, T; Wang, X; Wen, FQ; Xu, D; Zhang, SF, 2009) |
| "The subsequently pulmonary fibrosis was also decreased, but there was no statistically significance." | 1.30 | [The effect of aminoguanidine, a nitric oxide synthase inhibitor, on bleomycin-induced lung injury in rats]. ( Hu, J; Li, B; Xu, Q, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 7 (87.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, L | 1 |
| Wang, T | 1 |
| Wang, X | 1 |
| Sun, BB | 1 |
| Li, JQ | 1 |
| Liu, DS | 1 |
| Zhang, SF | 1 |
| Liu, L | 1 |
| Xu, D | 1 |
| Chen, YJ | 1 |
| Wen, FQ | 1 |
| Guo, H | 2 |
| Chen, XL | 4 |
| Chen, C | 2 |
| Jin, H | 2 |
| Li, SQ | 1 |
| Ai, J | 2 |
| Giri, SN | 1 |
| Biring, I | 1 |
| Nguyen, T | 1 |
| Wang, Q | 1 |
| Hyde, DM | 1 |
| Li, WB | 2 |
| Zhou, AM | 1 |
| Huang, SS | 2 |
| Yildirim, Z | 1 |
| Turkoz, Y | 1 |
| Kotuk, M | 1 |
| Armutcu, F | 1 |
| Gurel, A | 1 |
| Iraz, M | 1 |
| Ozen, S | 1 |
| Aydogdu, I | 1 |
| Akyol, O | 1 |
| Wang, DH | 1 |
| Wang, XL | 1 |
| Hu, J | 1 |
| Xu, Q | 1 |
| Li, B | 1 |
8 other studies available for pimagedine and Pulmonary Fibrosis
| Article | Year |
|---|---|
Blockade of advanced glycation end product formation attenuates bleomycin-induced pulmonary fibrosis in rats.
Topics: Animals; Antimetabolites, Antineoplastic; Bleomycin; Blotting, Western; Enzyme Inhibitors; Enzyme-Li | 2009 |
[Inhalation of aminoguanidine prevents the up-regulation of connective tissue growth factor in fibrotic lungs of rats].
Topics: Administration, Inhalation; Animals; Bleomycin; Connective Tissue Growth Factor; Guanidines; Lung; P | 2009 |
[The effects of aminoguanidine inhalation on bleomycin-induced fibrosis in lungs].
Topics: Administration, Inhalation; Animals; Bleomycin; Enzyme Inhibitors; Guanidines; Male; Nitric Oxide Sy | 2009 |
Abrogation of bleomycin-induced lung fibrosis by nitric oxide synthase inhibitor, aminoguanidine in mice.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Cell Count; Disease Models, Animal; Guanidines; Hy | 2002 |
Role of endogenous peroxynitrite in pulmonary injury and fibrosis induced by bleomycin A5 in rats.
Topics: Animals; Bleomycin; Collagen; Guanidines; Macrophages, Alveolar; Male; Malondialdehyde; Nitric Oxide | 2003 |
Effects of aminoguanidine and antioxidant erdosteine on bleomycin-induced lung fibrosis in rats.
Topics: Animals; Antioxidants; Bleomycin; Drug Therapy, Combination; Glutathione Peroxidase; Guanidines; Mal | 2004 |
Inhibitory effect of aminoguanidine on bleomycin-induced pulmonary toxicity in rat.
Topics: Animals; Bleomycin; Guanidines; Hydroxyproline; Lung; Male; Malondialdehyde; Nitric Oxide; Pulmonary | 2001 |
[The effect of aminoguanidine, a nitric oxide synthase inhibitor, on bleomycin-induced lung injury in rats].
Topics: Animals; Bleomycin; Enzyme Inhibitors; Female; Guanidines; Lung; Male; Malondialdehyde; Nitric Oxide | 1999 |