pimagedine has been researched along with Proteinuria in 15 studies
pimagedine: diamine oxidase & nitric oxide synthase inhibitor; an advanced glycosylation end product inhibitor; used in the treatment of diabetic complications; structure
aminoguanidine : A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.
Proteinuria: The presence of proteins in the urine, an indicator of KIDNEY DISEASES.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Urinary excretion of Na and NO metabolites (NOx), as well as immunodetectable endothelial (eNOS), inducible (iNOS) and neuronal (nNOS) NO synthases were determined in rats with puromycin aminonucleoside (PAN)-induced NS, rats with protein overload proteinuria, Nagase rats (NAR) with inherited analbuminemia, iNOS inhibitor (aminoguanidine)-treated rats, prenephrotic PAN-treated and placebo-treated control rats." | 3.72 | Downregulation of nitric oxide synthase in nephrotic syndrome: role of proteinuria. ( Ni, Z; Vaziri, ND, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (46.67) | 18.2507 |
| 2000's | 6 (40.00) | 29.6817 |
| 2010's | 2 (13.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hu, C | 1 |
| Cong, XD | 1 |
| Dai, DZ | 1 |
| Zhang, Y | 1 |
| Zhang, GL | 1 |
| Dai, Y | 1 |
| Schmaderer, C | 1 |
| Xing, CJ | 1 |
| Anderson, G | 1 |
| Hermans, R | 1 |
| Lutz, J | 1 |
| Heemann, U | 1 |
| Baumann, M | 1 |
| Ni, Z | 1 |
| Vaziri, ND | 1 |
| Yamabe, N | 2 |
| Kang, KS | 2 |
| Goto, E | 1 |
| Tanaka, T | 1 |
| Yokozawa, T | 2 |
| Kim, HY | 1 |
| Li, YM | 1 |
| Steffes, M | 1 |
| Donnelly, T | 1 |
| Liu, C | 1 |
| Fuh, H | 1 |
| Basgen, J | 1 |
| Bucala, R | 1 |
| Vlassara, H | 1 |
| Lubarsky, SL | 1 |
| Ahokas, RA | 1 |
| Friedman, SA | 1 |
| Sibai, BM | 1 |
| Brooks, DP | 1 |
| Contino, LC | 1 |
| Yang, CW | 1 |
| Yu, CC | 1 |
| Ko, YC | 1 |
| Huang, CC | 1 |
| Sugimoto, H | 1 |
| Shikata, K | 1 |
| Wada, J | 1 |
| Horiuchi, S | 1 |
| Makino, H | 1 |
| Unlüçerçi, YM | 1 |
| Bekpinar, S | 1 |
| Seferoglu, G | 1 |
| Rong, J | 1 |
| Qiu, H | 1 |
| Wang, S | 1 |
| Kelly, DJ | 1 |
| Aaltonen, P | 1 |
| Cox, AJ | 1 |
| Rumble, JR | 1 |
| Langham, R | 1 |
| Panagiotopoulos, S | 1 |
| Jerums, G | 1 |
| Holthöfer, H | 1 |
| Gilbert, RE | 1 |
| Itakura, M | 1 |
| Yoshikawa, H | 1 |
| Bannai, C | 1 |
| Kato, M | 1 |
| Kunika, K | 1 |
| Kawakami, Y | 1 |
| Yamaoka, T | 1 |
| Yamashita, K | 1 |
| Lubec, G | 1 |
| Bartosch, B | 1 |
| Mallinger, R | 1 |
| Adamiker, D | 1 |
| Graef, I | 1 |
| Frisch, H | 1 |
| Höger, H | 1 |
15 other studies available for pimagedine and Proteinuria
| Article | Year |
|---|---|
Argirein alleviates diabetic nephropathy through attenuating NADPH oxidase, Cx43, and PERK in renal tissue.
Topics: Animals; Anthraquinones; Aspartic Acid Endopeptidases; Blood Glucose; Blood Urea Nitrogen; Connexin | 2011 |
AGE formation blockade with aminoguanidine does not ameliorate chronic allograft nephropathy.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Cardiotonic Ag | 2011 |
Downregulation of nitric oxide synthase in nephrotic syndrome: role of proteinuria.
Topics: Animals; Chlorides; Creatinine; Down-Regulation; Enzyme Inhibitors; Gene Expression Regulation, Enzy | 2003 |
Beneficial effect of Corni Fructus, a constituent of Hachimi-jio-gan, on advanced glycation end-product-mediated renal injury in Streptozotocin-treated diabetic rats.
Topics: Administration, Oral; Animals; Blood Glucose; Blotting, Western; Cornus; Creatinine; Diabetes Mellit | 2007 |
Role of maltol in advanced glycation end products and free radicals: in-vitro and in-vivo studies.
Topics: Animals; Blood Glucose; Creatinine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Electro | 2008 |
Prevention of cardiovascular and renal pathology of aging by the advanced glycation inhibitor aminoguanidine.
Topics: Acetylcholine; Aging; Animals; Aorta; Blood Pressure; Body Weight; Cardiomegaly; Creatinine; Enzyme | 1996 |
The effect of chronic nitric oxide synthesis inhibition on blood pressure and angiotensin II responsiveness in the pregnant rat.
Topics: Angiotensin II; Animals; Blood Pressure; Enzyme Inhibitors; Female; Guanidines; Heart Rate; Hematocr | 1997 |
Involvement of nitric oxide synthase in proteinuria associated with chronic renal disease in rats.
Topics: Animals; Blood Pressure; Blood Urea Nitrogen; Creatinine; Enzyme Inhibitors; Guanidines; Kidney Fail | 1998 |
Aminoguanidine reduces glomerular inducible nitric oxide synthase (iNOS) and transforming growth factor-beta 1 (TGF-beta1) mRNA expression and diminishes glomerulosclerosis in NZB/W F1 mice.
Topics: Animals; Body Weight; Cell Count; Creatine; Crosses, Genetic; Enzyme Inhibitors; Female; Guanidines; | 1998 |
Advanced glycation end products-cytokine-nitric oxide sequence pathway in the development of diabetic nephropathy: aminoguanidine ameliorates the overexpression of tumour necrosis factor-alpha and inducible nitric oxide synthase in diabetic rat glomeruli.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Fructosamin | 1999 |
The effect of aminoguanidine on urinary heparan sulphate levels in experimental diabetes.
Topics: Animals; Basement Membrane; Diabetes Mellitus, Experimental; Glycation End Products, Advanced; Guani | 2000 |
Advanced glycosylation end products, protein kinase C and renal alterations in diabetic rats.
Topics: Animals; Basement Membrane; Blood Glucose; Creatinine; Diabetes Mellitus, Experimental; Glycated Hem | 2000 |
Expression of the slit-diaphragm protein, nephrin, in experimental diabetic nephropathy: differing effects of anti-proteinuric therapies.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Base Sequence; Diabetes Mellitus, Experimental; D | 2002 |
Aminoguanidine decreases urinary albumin and high-molecular-weight proteins in diabetic rats.
Topics: Albuminuria; Analysis of Variance; Animals; Blood Glucose; Body Weight; Collagen; Diabetes Mellitus, | 1991 |
The effect of substance L on glucose-mediated cross-links of collagen in the diabetic db/db mouse.
Topics: Administration, Oral; Amino Acids; Animals; Collagen; Diabetes Mellitus, Experimental; Electrophores | 1990 |