pimagedine has been researched along with Poliomyelitis in 1 studies
pimagedine: diamine oxidase & nitric oxide synthase inhibitor; an advanced glycosylation end product inhibitor; used in the treatment of diabetic complications; structure
aminoguanidine : A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.
Poliomyelitis: An acute infectious disease of humans, particularly children, caused by any of three serotypes of human poliovirus (POLIOVIRUS). Usually the infection is limited to the gastrointestinal tract and nasopharynx, and is often asymptomatic. The central nervous system, primarily the spinal cord, may be affected, leading to rapidly progressive paralysis, coarse FASCICULATION and hyporeflexia. Motor neurons are primarily affected. Encephalitis may also occur. The virus replicates in the nervous system, and may cause significant neuronal loss, most notably in the spinal cord. A rare related condition, nonpoliovirus poliomyelitis, may result from infections with nonpoliovirus enteroviruses. (From Adams et al., Principles of Neurology, 6th ed, pp764-5)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Inflammation, demyelination and axonal necrosis were scored in a blinded fashion on spinal cord sections from each mouse." | 1.30 | Nitric oxide synthase inhibitor, aminoguanidine, reduces inflammation and demyelination produced by Theiler's virus infection. ( Cross, AH; Fujinami, RS; Hill, KE; Kurtz, CI; Rose, JW; Tsunoda, I; Wada, Y, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rose, JW | 1 |
| Hill, KE | 1 |
| Wada, Y | 1 |
| Kurtz, CI | 1 |
| Tsunoda, I | 1 |
| Fujinami, RS | 1 |
| Cross, AH | 1 |
1 other study available for pimagedine and Poliomyelitis
| Article | Year |
|---|---|
Nitric oxide synthase inhibitor, aminoguanidine, reduces inflammation and demyelination produced by Theiler's virus infection.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Axons; Demyelinating Diseases; DNA Frag | 1998 |