pimagedine has been researched along with Optic Nerve Diseases in 2 studies
pimagedine: diamine oxidase & nitric oxide synthase inhibitor; an advanced glycosylation end product inhibitor; used in the treatment of diabetic complications; structure
aminoguanidine : A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.
Optic Nerve Diseases: Conditions which produce injury or dysfunction of the second cranial or optic nerve, which is generally considered a component of the central nervous system. Damage to optic nerve fibers may occur at or near their origin in the retina, at the optic disk, or in the nerve, optic chiasm, optic tract, or lateral geniculate nuclei. Clinical manifestations may include decreased visual acuity and contrast sensitivity, impaired color vision, and an afferent pupillary defect.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pang, IH | 1 |
| Johnson, EC | 1 |
| Jia, L | 1 |
| Cepurna, WO | 1 |
| Shepard, AR | 1 |
| Hellberg, MR | 1 |
| Clark, AF | 1 |
| Morrison, JC | 1 |
| Ino-ue, M | 1 |
| Ohgiya, N | 1 |
| Yamamoto, M | 1 |
2 other studies available for pimagedine and Optic Nerve Diseases
| Article | Year |
|---|---|
Evaluation of inducible nitric oxide synthase in glaucomatous optic neuropathy and pressure-induced optic nerve damage.
Topics: Aged; Animals; Caenorhabditis elegans Proteins; Disease Models, Animal; Enzyme Inhibitors; Gene Expr | 2005 |
Effect of aminoguanidine on optic nerve involvement in experimental diabetic rats.
Topics: Animals; Body Weight; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Dose-Response Relation | 1998 |