Page last updated: 2024-10-22

pimagedine and Obesity

pimagedine has been researched along with Obesity in 9 studies

pimagedine: diamine oxidase & nitric oxide synthase inhibitor; an advanced glycosylation end product inhibitor; used in the treatment of diabetic complications; structure
aminoguanidine : A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.

Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).

Research Excerpts

ExcerptRelevanceReference
" The AMP-activated protein kinase (AMPK) activator metformin reverses obesity-associated insulin resistance (IR) and inhibits different types of inflammatory responses."7.79Metformin attenuates the exacerbation of the allergic eosinophilic inflammation in high fat-diet-induced obesity in mice. ( André, DM; Anhê, GF; Antunes, E; Bordin, S; Calixto, MC; Ferreira, D; Landgraf, RG; Leiria, LO; Lellis-Santos, C; Lintomen, L, 2013)
" Obesity was induced by the administration of 4 mg/g body weight of monosodium glutamate (MSG) or equimolar saline (CTR) in newborn rats."3.85iNOS inhibition improves autonomic dysfunction and oxidative status in hypertensive obese rats. ( Cecchini, R; da Cunha, NV; Lopes, FN; Martins-Pinge, MC; Panis, C; Pinge-Filho, P, 2017)
" The AMP-activated protein kinase (AMPK) activator metformin reverses obesity-associated insulin resistance (IR) and inhibits different types of inflammatory responses."3.79Metformin attenuates the exacerbation of the allergic eosinophilic inflammation in high fat-diet-induced obesity in mice. ( André, DM; Anhê, GF; Antunes, E; Bordin, S; Calixto, MC; Ferreira, D; Landgraf, RG; Leiria, LO; Lellis-Santos, C; Lintomen, L, 2013)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (22.22)18.2507
2000's4 (44.44)29.6817
2010's3 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Calixto, MC1
Lintomen, L1
André, DM1
Leiria, LO1
Ferreira, D1
Lellis-Santos, C1
Anhê, GF1
Bordin, S1
Landgraf, RG1
Antunes, E1
da Cunha, NV1
Lopes, FN1
Panis, C1
Cecchini, R1
Pinge-Filho, P1
Martins-Pinge, MC1
Gaens, KH1
Niessen, PM1
Rensen, SS1
Buurman, WA1
Greve, JW1
Driessen, A1
Wolfs, MG1
Hofker, MH1
Bloemen, JG1
Dejong, CH1
Stehouwer, CD1
Schalkwijk, CG1
Cioni, L1
De Siena, G1
Ghelardini, C1
Sernissi, O1
Alfarano, C1
Pirisino, R1
Raimondi, L1
Prévot, D1
Soltesz, Z1
Abello, V1
Wanecq, E1
Valet, P1
Unzeta, M1
Carpéné, C1
Hemmrich, K1
Thomas, GP1
Abberton, KM1
Thompson, EW1
Rophael, JA1
Penington, AJ1
Morrison, WA1
Shimabukuro, M2
Ohneda, M1
Lee, Y1
Unger, RH2
Zhou, YT1
Levi, M1
Wongmekiat, O1
Johns, EJ1

Other Studies

9 other studies available for pimagedine and Obesity

ArticleYear
Metformin attenuates the exacerbation of the allergic eosinophilic inflammation in high fat-diet-induced obesity in mice.
    PloS one, 2013, Volume: 8, Issue:10

    Topics: AMP-Activated Protein Kinases; Animals; Asthma; Blotting, Western; Bronchoalveolar Lavage Fluid; Die

2013
iNOS inhibition improves autonomic dysfunction and oxidative status in hypertensive obese rats.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2017, Volume: 39, Issue:1

    Topics: Animals; Arterial Pressure; Autonomic Nervous System; Dinoprostone; Enzyme Inhibitors; Guanidines; H

2017
Endogenous formation of Nε-(carboxymethyl)lysine is increased in fatty livers and induces inflammatory markers in an in vitro model of hepatic steatosis.
    Journal of hepatology, 2012, Volume: 56, Issue:3

    Topics: Aged; Biomarkers; Biopsy; Cytokines; Enzyme Inhibitors; Fatty Liver; Female; Gene Expression; Guanid

2012
Activity and expression of semicarbazide-sensitive benzylamine oxidase in a rodent model of diabetes: interactive effects with methylamine and alpha-aminoguanidine.
    European journal of pharmacology, 2006, Jan-04, Volume: 529, Issue:1-3

    Topics: Adipose Tissue; Amine Oxidase (Copper-Containing); Animals; Appetite Depressants; Brain; Diabetes Me

2006
Prolonged treatment with aminoguanidine strongly inhibits adipocyte semicarbazide-sensitive amine oxidase and slightly reduces fat deposition in obese Zucker rats.
    Pharmacological research, 2007, Volume: 56, Issue:1

    Topics: 3T3 Cells; Adipocytes; Adipose Tissue, White; Adult; Amine Oxidase (Copper-Containing); Animals; Ben

2007
Monocyte chemoattractant protein-1 and nitric oxide promote adipogenesis in a model that mimics obesity.
    Obesity (Silver Spring, Md.), 2007, Volume: 15, Issue:12

    Topics: Adipogenesis; Adipose Tissue; Animals; Cell Movement; Chemokine CCL2; Disease Models, Animal; Enzyme

2007
Role of nitric oxide in obesity-induced beta cell disease.
    The Journal of clinical investigation, 1997, Jul-15, Volume: 100, Issue:2

    Topics: Animals; Blood Glucose; Cells, Cultured; Diabetes Mellitus; Diabetes Mellitus, Type 2; Fatty Acids,

1997
Fatty acid-induced beta cell apoptosis: a link between obesity and diabetes.
    Proceedings of the National Academy of Sciences of the United States of America, 1998, Mar-03, Volume: 95, Issue:5

    Topics: Animals; Apoptosis; Cells, Cultured; Ceramides; Chromans; Coenzyme A Ligases; Diabetes Mellitus; Dia

1998
Interactions between nitric oxide and renal nerves in the excretion of a saline load in obese Zucker rats.
    Clinical science (London, England : 1979), 2001, Volume: 101, Issue:3

    Topics: Animals; Blood Glucose; Diuresis; Enzyme Inhibitors; Guanidines; Hemodynamics; Indazoles; Kidney; Ma

2001