pimagedine has been researched along with Obesity in 9 studies
pimagedine: diamine oxidase & nitric oxide synthase inhibitor; an advanced glycosylation end product inhibitor; used in the treatment of diabetic complications; structure
aminoguanidine : A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.
Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
| Excerpt | Relevance | Reference |
|---|---|---|
| " The AMP-activated protein kinase (AMPK) activator metformin reverses obesity-associated insulin resistance (IR) and inhibits different types of inflammatory responses." | 7.79 | Metformin attenuates the exacerbation of the allergic eosinophilic inflammation in high fat-diet-induced obesity in mice. ( André, DM; Anhê, GF; Antunes, E; Bordin, S; Calixto, MC; Ferreira, D; Landgraf, RG; Leiria, LO; Lellis-Santos, C; Lintomen, L, 2013) |
| " Obesity was induced by the administration of 4 mg/g body weight of monosodium glutamate (MSG) or equimolar saline (CTR) in newborn rats." | 3.85 | iNOS inhibition improves autonomic dysfunction and oxidative status in hypertensive obese rats. ( Cecchini, R; da Cunha, NV; Lopes, FN; Martins-Pinge, MC; Panis, C; Pinge-Filho, P, 2017) |
| " The AMP-activated protein kinase (AMPK) activator metformin reverses obesity-associated insulin resistance (IR) and inhibits different types of inflammatory responses." | 3.79 | Metformin attenuates the exacerbation of the allergic eosinophilic inflammation in high fat-diet-induced obesity in mice. ( André, DM; Anhê, GF; Antunes, E; Bordin, S; Calixto, MC; Ferreira, D; Landgraf, RG; Leiria, LO; Lellis-Santos, C; Lintomen, L, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 4 (44.44) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Calixto, MC | 1 |
| Lintomen, L | 1 |
| André, DM | 1 |
| Leiria, LO | 1 |
| Ferreira, D | 1 |
| Lellis-Santos, C | 1 |
| Anhê, GF | 1 |
| Bordin, S | 1 |
| Landgraf, RG | 1 |
| Antunes, E | 1 |
| da Cunha, NV | 1 |
| Lopes, FN | 1 |
| Panis, C | 1 |
| Cecchini, R | 1 |
| Pinge-Filho, P | 1 |
| Martins-Pinge, MC | 1 |
| Gaens, KH | 1 |
| Niessen, PM | 1 |
| Rensen, SS | 1 |
| Buurman, WA | 1 |
| Greve, JW | 1 |
| Driessen, A | 1 |
| Wolfs, MG | 1 |
| Hofker, MH | 1 |
| Bloemen, JG | 1 |
| Dejong, CH | 1 |
| Stehouwer, CD | 1 |
| Schalkwijk, CG | 1 |
| Cioni, L | 1 |
| De Siena, G | 1 |
| Ghelardini, C | 1 |
| Sernissi, O | 1 |
| Alfarano, C | 1 |
| Pirisino, R | 1 |
| Raimondi, L | 1 |
| Prévot, D | 1 |
| Soltesz, Z | 1 |
| Abello, V | 1 |
| Wanecq, E | 1 |
| Valet, P | 1 |
| Unzeta, M | 1 |
| Carpéné, C | 1 |
| Hemmrich, K | 1 |
| Thomas, GP | 1 |
| Abberton, KM | 1 |
| Thompson, EW | 1 |
| Rophael, JA | 1 |
| Penington, AJ | 1 |
| Morrison, WA | 1 |
| Shimabukuro, M | 2 |
| Ohneda, M | 1 |
| Lee, Y | 1 |
| Unger, RH | 2 |
| Zhou, YT | 1 |
| Levi, M | 1 |
| Wongmekiat, O | 1 |
| Johns, EJ | 1 |
9 other studies available for pimagedine and Obesity
| Article | Year |
|---|---|
Metformin attenuates the exacerbation of the allergic eosinophilic inflammation in high fat-diet-induced obesity in mice.
Topics: AMP-Activated Protein Kinases; Animals; Asthma; Blotting, Western; Bronchoalveolar Lavage Fluid; Die | 2013 |
iNOS inhibition improves autonomic dysfunction and oxidative status in hypertensive obese rats.
Topics: Animals; Arterial Pressure; Autonomic Nervous System; Dinoprostone; Enzyme Inhibitors; Guanidines; H | 2017 |
Endogenous formation of Nε-(carboxymethyl)lysine is increased in fatty livers and induces inflammatory markers in an in vitro model of hepatic steatosis.
Topics: Aged; Biomarkers; Biopsy; Cytokines; Enzyme Inhibitors; Fatty Liver; Female; Gene Expression; Guanid | 2012 |
Activity and expression of semicarbazide-sensitive benzylamine oxidase in a rodent model of diabetes: interactive effects with methylamine and alpha-aminoguanidine.
Topics: Adipose Tissue; Amine Oxidase (Copper-Containing); Animals; Appetite Depressants; Brain; Diabetes Me | 2006 |
Prolonged treatment with aminoguanidine strongly inhibits adipocyte semicarbazide-sensitive amine oxidase and slightly reduces fat deposition in obese Zucker rats.
Topics: 3T3 Cells; Adipocytes; Adipose Tissue, White; Adult; Amine Oxidase (Copper-Containing); Animals; Ben | 2007 |
Monocyte chemoattractant protein-1 and nitric oxide promote adipogenesis in a model that mimics obesity.
Topics: Adipogenesis; Adipose Tissue; Animals; Cell Movement; Chemokine CCL2; Disease Models, Animal; Enzyme | 2007 |
Role of nitric oxide in obesity-induced beta cell disease.
Topics: Animals; Blood Glucose; Cells, Cultured; Diabetes Mellitus; Diabetes Mellitus, Type 2; Fatty Acids, | 1997 |
Fatty acid-induced beta cell apoptosis: a link between obesity and diabetes.
Topics: Animals; Apoptosis; Cells, Cultured; Ceramides; Chromans; Coenzyme A Ligases; Diabetes Mellitus; Dia | 1998 |
Interactions between nitric oxide and renal nerves in the excretion of a saline load in obese Zucker rats.
Topics: Animals; Blood Glucose; Diuresis; Enzyme Inhibitors; Guanidines; Hemodynamics; Indazoles; Kidney; Ma | 2001 |