pimagedine has been researched along with Nephrotic Syndrome in 3 studies
pimagedine: diamine oxidase & nitric oxide synthase inhibitor; an advanced glycosylation end product inhibitor; used in the treatment of diabetic complications; structure
aminoguanidine : A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.
Nephrotic Syndrome: A condition characterized by severe PROTEINURIA, greater than 3.5 g/day in an average adult. The substantial loss of protein in the urine results in complications such as HYPOPROTEINEMIA; generalized EDEMA; HYPERTENSION; and HYPERLIPIDEMIAS. Diseases associated with nephrotic syndrome generally cause chronic kidney dysfunction.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Urinary excretion of Na and NO metabolites (NOx), as well as immunodetectable endothelial (eNOS), inducible (iNOS) and neuronal (nNOS) NO synthases were determined in rats with puromycin aminonucleoside (PAN)-induced NS, rats with protein overload proteinuria, Nagase rats (NAR) with inherited analbuminemia, iNOS inhibitor (aminoguanidine)-treated rats, prenephrotic PAN-treated and placebo-treated control rats." | 3.72 | Downregulation of nitric oxide synthase in nephrotic syndrome: role of proteinuria. ( Ni, Z; Vaziri, ND, 2003) |
| "Puromycin aminonucleoside (PAN) administration in rats produces an experimental model of nephrotic syndrome characterized by glomerular epithelial cell injury and proteinuria." | 3.70 | Lack of a role for inducible nitric oxide synthase in an experimental model of nephrotic syndrome. ( Mayeux, PR; Shah, SV; Walker, LM, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ni, Z | 1 |
| Vaziri, ND | 1 |
| Walker, LM | 1 |
| Shah, SV | 1 |
| Mayeux, PR | 1 |
| Ozen, S | 1 |
| Usta, Y | 1 |
| Sahin-Erdemli, I | 1 |
| Orhan, D | 1 |
| Gumusel, B | 1 |
| Yang, B | 1 |
| Gursoy, Y | 1 |
| Tulunay, O | 1 |
| Dalkara, T | 1 |
| Bakkaloglu, A | 1 |
| El-Nahas, M | 1 |
3 other studies available for pimagedine and Nephrotic Syndrome
| Article | Year |
|---|---|
Downregulation of nitric oxide synthase in nephrotic syndrome: role of proteinuria.
Topics: Animals; Chlorides; Creatinine; Down-Regulation; Enzyme Inhibitors; Gene Expression Regulation, Enzy | 2003 |
Lack of a role for inducible nitric oxide synthase in an experimental model of nephrotic syndrome.
Topics: Animals; Enzyme Inhibitors; Guanidines; Male; Nephrotic Syndrome; Nitric Oxide; Nitric Oxide Synthas | 2000 |
Association of nitric oxide production and apoptosis in a model of experimental nephropathy.
Topics: Animals; Apoptosis; Doxorubicin; Enzyme Inhibitors; Guanidines; In Vitro Techniques; Nephrotic Syndr | 2001 |