pimagedine has been researched along with Multiple Myeloma in 2 studies
pimagedine: diamine oxidase & nitric oxide synthase inhibitor; an advanced glycosylation end product inhibitor; used in the treatment of diabetic complications; structure
aminoguanidine : A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.
Multiple Myeloma: A malignancy of mature PLASMA CELLS engaging in monoclonal immunoglobulin production. It is characterized by hyperglobulinemia, excess Bence-Jones proteins (free monoclonal IMMUNOGLOBULIN LIGHT CHAINS) in the urine, skeletal destruction, bone pain, and fractures. Other features include ANEMIA; HYPERCALCEMIA; and RENAL INSUFFICIENCY.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Erez, O | 1 |
| Goldstaub, D | 1 |
| Friedman, J | 1 |
| Kahana, C | 2 |
| Tobias, KE | 1 |
2 other studies available for pimagedine and Multiple Myeloma
| Article | Year |
|---|---|
Putrescine activates oxidative stress dependent apoptotic death in ornithine decarboxylase overproducing mouse myeloma cells.
Topics: Animals; Apoptosis; Blotting, Western; Calcium; Caspase 2; Caspases; Chelating Agents; Cytochrome c | 2002 |
Exposure to ornithine results in excessive accumulation of putrescine and apoptotic cell death in ornithine decarboxylase overproducing mouse myeloma cells.
Topics: Amine Oxidase (Copper-Containing); Animals; Apoptosis; Biogenic Polyamines; Cell Size; Cell Survival | 1995 |