pimagedine has been researched along with Meniere Disease in 1 studies
pimagedine: diamine oxidase & nitric oxide synthase inhibitor; an advanced glycosylation end product inhibitor; used in the treatment of diabetic complications; structure
aminoguanidine : A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.
Meniere Disease: A disease of the inner ear (LABYRINTH) that is characterized by fluctuating SENSORINEURAL HEARING LOSS; TINNITUS; episodic VERTIGO; and aural fullness. It is the most common form of endolymphatic hydrops.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Aminoguanidine treated animals (n = 5) also sustained nerve deterioration to the same degree as non-treated animals and there appeared to be no protective effect (at the dosage administered) against ELH related hearing loss, hydrops formation, or nerve deterioration." | 1.33 | Diameter of the cochlear nerve in endolymphatic hydrops: implications for the etiology of hearing loss in Ménière's disease. ( Megerian, CA, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Megerian, CA | 1 |
1 other study available for pimagedine and Meniere Disease
| Article | Year |
|---|---|
Diameter of the cochlear nerve in endolymphatic hydrops: implications for the etiology of hearing loss in Ménière's disease.
Topics: Animals; Cochlear Nerve; Endolymphatic Hydrops; Enzyme Inhibitors; Female; Guanidines; Guinea Pigs; | 2005 |