pimagedine has been researched along with Koch's Disease in 6 studies
pimagedine: diamine oxidase & nitric oxide synthase inhibitor; an advanced glycosylation end product inhibitor; used in the treatment of diabetic complications; structure
aminoguanidine : A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We have recently demonstrated that the macrophage L-arginine-dependent cytotoxic pathway effectively kills the virulent Erdman strain of Mycobacterium tuberculosis in vitro via the generation of toxic reactive nitrogen intermediates by the enzyme nitric oxide synthase." | 3.69 | Effects of nitric oxide synthase inhibitors on murine infection with Mycobacterium tuberculosis. ( Bloom, BR; Carroll, D; Chan, J; Flynn, J; Tanaka, K, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Botha, T | 1 |
| Ryffel, B | 1 |
| Tufariello, JM | 1 |
| Mi, K | 1 |
| Xu, J | 1 |
| Manabe, YC | 1 |
| Kesavan, AK | 1 |
| Drumm, J | 1 |
| Tanaka, K | 2 |
| Jacobs, WR | 1 |
| Chan, J | 3 |
| Carroll, D | 1 |
| Flynn, J | 1 |
| Bloom, BR | 1 |
| Flynn, JL | 1 |
| Scanga, CA | 1 |
| Tanaka, KE | 1 |
| Rojas, M | 1 |
| Barrera, LF | 1 |
| García, LF | 1 |
6 other studies available for pimagedine and Koch's Disease
| Article | Year |
|---|---|
[SIMULATION OF CHRONIC TUBERCULOSIS INFECTION IN MICE BY INTRAPERITONEAL INOCULATION AND THE TESTING OF AMINOGUANIDINE-INDUCED ACTIVATION OF RPF GENE/DELETION MUTANTS OF THE H37Rv STRAIN].
Topics: Animals; Bacterial Proteins; Bacterial Typing Techniques; Cytokines; Disease Models, Animal; Enzyme | 2010 |
Reactivation of latent tuberculosis by an inhibitor of inducible nitric oxide synthase in an aerosol murine model.
Topics: Animals; Antitubercular Agents; Chronic Disease; Disease Models, Animal; Enzyme Inhibitors; Guanidin | 2002 |
Deletion of the Mycobacterium tuberculosis resuscitation-promoting factor Rv1009 gene results in delayed reactivation from chronic tuberculosis.
Topics: Animals; B-Lymphocytes; Bacterial Proteins; Chronic Disease; Cytokines; Female; Guanidines; Lung; Mi | 2006 |
Effects of nitric oxide synthase inhibitors on murine infection with Mycobacterium tuberculosis.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Guanidines; Mice; Mice, Inbred C57BL; Mycobacterium t | 1995 |
Effects of aminoguanidine on latent murine tuberculosis.
Topics: Animals; Cytokines; Disease Models, Animal; Dose-Response Relationship, Immunologic; Enzyme Inductio | 1998 |
Induction of apoptosis in murine macrophages by Mycobacterium tuberculosis is reactive oxygen intermediates-independent.
Topics: Animals; Apoptosis; Cell Line; Enzyme Inhibitors; Free Radical Scavengers; Guanidines; Macrophages; | 1998 |