Page last updated: 2024-10-22

pimagedine and Ischemia

pimagedine has been researched along with Ischemia in 24 studies

pimagedine: diamine oxidase & nitric oxide synthase inhibitor; an advanced glycosylation end product inhibitor; used in the treatment of diabetic complications; structure
aminoguanidine : A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.

Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.

Research Excerpts

ExcerptRelevanceReference
"This study aimed to examine the relationship between a harmful effect of histamine and apoptosis following ischemia-reperfusion in the rat intestine."7.70Histaminergic effect on apoptosis of rat small intestinal mucosa after ischemia-reperfusion. ( Fujimoto, K; Fukuyama, K; Iwakiri, R; Kojima, M; Noda, T; Okamoto, K; Yoshida, T, 2000)
"Recent studies have demonstrated a connection between xanthine oxidase-generated reactive oxygen intermediates and histamine release during ischemia-reperfusion."7.68Studies on the relationship between xanthine oxidase and histamine release during intestinal ischemia-reperfusion. ( Bakó, L; Boros, M; Kaszaki, J; Nagy, S, 1992)
" A monoexponential dose-response relationship was found between the specific diamine oxidase inhibitor aminoguanidine and reduced survival time."5.26Intestinal diamine oxidase and histamine release in rabbit mesenteric ischemia. ( Hesterberg, R; Hinterlang, E; Kusche, J; Lorenz, W; Ohmann, C; Richter, H; Schmal, A; Stahlknecht, CD; Weber, D, 1981)
" Our study was designed to investigate the involvement of MMPs and of tissue inhibitors of metalloproteinases (TIMPs) in rat retinal ischemic injury, the effect of nitric oxide synthase (NOS) inhibitors on MMPs' activity in this model and whether minocycline (an MMP inhibitor) is protective in retinal ischemia."3.74The involvement of matrix metalloproteinases 2 and 9 in rat retinal ischemia. ( Bahar-Shany, K; Geyer, O; Lahat, N; Mathalone, N; Oron, Y; Rahat, MA, 2007)
"This study aimed to examine the relationship between a harmful effect of histamine and apoptosis following ischemia-reperfusion in the rat intestine."3.70Histaminergic effect on apoptosis of rat small intestinal mucosa after ischemia-reperfusion. ( Fujimoto, K; Fukuyama, K; Iwakiri, R; Kojima, M; Noda, T; Okamoto, K; Yoshida, T, 2000)
"Recent studies have demonstrated a connection between xanthine oxidase-generated reactive oxygen intermediates and histamine release during ischemia-reperfusion."3.68Studies on the relationship between xanthine oxidase and histamine release during intestinal ischemia-reperfusion. ( Bakó, L; Boros, M; Kaszaki, J; Nagy, S, 1992)
"Brief ischemia was reported to protect retinal cells against injury induced by subsequent ischemia-reperfusion with de novo protein synthesis, and this phenomenon is known as late ischemic preconditioning."1.33Inducible nitric oxide synthase inhibitors abolished histological protection by late ischemic preconditioning in rat retina. ( Ishii, K; Kubota, Y; Kuwagata, M; Nakahara, T; Saito, M; Sakamoto, K; Yonoki, Y, 2006)
"After 8 weeks of treatment, hindlimb ischemia was induced by right femoral artery ligature."1.32Blockade of advanced glycation end-product formation restores ischemia-induced angiogenesis in diabetic mice. ( Benessiano, J; Duriez, M; Ebrahimian, TG; Huijberts, M; Lévy, BI; Silvestre, JS; Tamarat, R; Wautier, JL; Wautier, MP, 2003)
"Sepsis was induced by the intravenous administration of E."1.31Hemodynamic, biochemical and morphological changes induced by aminoguanidine in normal and septic sheep. ( Delgado, MA; Esteban, A; Fernández-Segoviano, P; Jara, N; Lorente, JA; Moscoso, A; Rodríguez-Corcos, A; Tejedor, C; Tobalina, R, 2000)
" A monoexponential dose-response relationship was found between the specific diamine oxidase inhibitor aminoguanidine and reduced survival time."1.26Intestinal diamine oxidase and histamine release in rabbit mesenteric ischemia. ( Hesterberg, R; Hinterlang, E; Kusche, J; Lorenz, W; Ohmann, C; Richter, H; Schmal, A; Stahlknecht, CD; Weber, D, 1981)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19902 (8.33)18.7374
1990's8 (33.33)18.2507
2000's12 (50.00)29.6817
2010's2 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Shin, JK1
Kang, JW1
Lee, SM1
Takizawa, Y1
Kitazato, T1
Ishizaka, H1
Kamiya, N1
Tomita, M1
Hayashi, M1
Neufeld, AH1
Kawai, Si1
Das, S1
Vora, S1
Gachie, E1
Connor, JR1
Manning, PT1
Badhwar, A1
Dungey, AA1
Harris, KA2
Scott, JA2
McCarter, SD1
Scott, JR1
Forbes, TL1
Potter, RF2
Tamarat, R1
Silvestre, JS1
Huijberts, M1
Benessiano, J1
Ebrahimian, TG1
Duriez, M1
Wautier, MP1
Wautier, JL1
Lévy, BI1
Sakamoto, K1
Yonoki, Y1
Kubota, Y1
Kuwagata, M1
Saito, M1
Nakahara, T1
Ishii, K1
Mathalone, N1
Lahat, N1
Rahat, MA1
Bahar-Shany, K1
Oron, Y2
Geyer, O2
Joviliano, EE1
Piccinato, CE1
Cherri, J1
Viaro, F1
Moryia, T1
Celotto, AC1
Bonaventura, D1
Evora, PR1
Uchida, K1
Mishima, S1
Ohta, S1
Yukioka, T1
Kusche, J2
Lorenz, W2
Stahlknecht, CD2
Richter, H2
Hesterberg, R1
Schmal, A1
Hinterlang, E1
Weber, D1
Ohmann, C1
Conger, J1
Robinette, J1
Villar, A1
Raij, L1
Shultz, P1
Almog, J1
Lupu-Meiri, M1
Lazar, M1
Kaszaki, J2
Boros, M2
Szabó, A1
Nagy, S2
Oshima, H2
Inoue, H1
Aihara, M1
Tomioka, M1
Ishida, H1
Pudupakkam, S1
Jamieson, WG1
DeRose, G1
Carson, MW1
Schlag, MG1
Kvietys, PR1
Tassiopoulos, AK1
Hakim, TS1
Finck, CM1
Pedoto, A1
Hodell, MG1
Landas, SK1
McGraw, DJ1
Chen, JC1
Chen, HM1
Shyr, MH1
Fan, LL1
Chi, TY1
Chi, CP1
Chen, MF1
Yoshida, T1
Iwakiri, R1
Noda, T1
Okamoto, K1
Kojima, M1
Fukuyama, K1
Fujimoto, K1
Wang, Y1
Xu, H1
Mizoguchi, K1
Oe, M1
Maeta, H1
Lorente, JA1
Tejedor, C1
Delgado, MA1
Fernández-Segoviano, P1
Jara, N1
Tobalina, R1
Rodríguez-Corcos, A1
Moscoso, A1
Esteban, A1
Tsuji, S1
Tabuchi, K1
Hara, A1
Kusakari, J1
Reichert, G1
Bakó, L1

Other Studies

24 other studies available for pimagedine and Ischemia

ArticleYear
Enhanced nitric oxide-mediated autophagy contributes to the hepatoprotective effects of ischemic preconditioning during ischemia and reperfusion.
    Nitric oxide : biology and chemistry, 2016, 08-31, Volume: 58

    Topics: Animals; Autophagy; Chloroquine; Guanidines; Imidazoles; Ischemia; Ischemic Preconditioning; Liver;

2016
Effect of aminoguanidine on ischemia/reperfusion injury in rat small intestine.
    Biological & pharmaceutical bulletin, 2011, Volume: 34, Issue:11

    Topics: Animals; Area Under Curve; Enzyme Inhibitors; Guanidines; Intestine, Small; Ischemia; Male; Nitric O

2011
Loss of retinal ganglion cells following retinal ischemia: the role of inducible nitric oxide synthase.
    Experimental eye research, 2002, Volume: 75, Issue:5

    Topics: Animals; Enzyme Inhibitors; Guanidines; Homoarginine; Ischemia; Male; Necrosis; Neutrophils; Nitric

2002
Limitations of ischemic tolerance in oxidative skeletal muscle: perfusion vs tissue protection.
    The Journal of surgical research, 2003, Volume: 109, Issue:1

    Topics: Animals; Calcium; Enzyme Inhibitors; Guanidines; Ischemia; Ischemic Preconditioning; Male; Microcirc

2003
Blockade of advanced glycation end-product formation restores ischemia-induced angiogenesis in diabetic mice.
    Proceedings of the National Academy of Sciences of the United States of America, 2003, Jul-08, Volume: 100, Issue:14

    Topics: Angiography; Animals; Collagen; Collagenases; Collateral Circulation; Diabetes Mellitus, Experimenta

2003
Inducible nitric oxide synthase inhibitors abolished histological protection by late ischemic preconditioning in rat retina.
    Experimental eye research, 2006, Volume: 82, Issue:3

    Topics: Animals; Enzyme Inhibitors; Guanidines; Indazoles; Ischemia; Ischemic Preconditioning; Lysine; Male;

2006
The involvement of matrix metalloproteinases 2 and 9 in rat retinal ischemia.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2007, Volume: 245, Issue:5

    Topics: Animals; Blotting, Western; Disease Models, Animal; Enzyme Inhibitors; Guanidines; Ischemia; Male; M

2007
In vitro pharmacological study of femoral artery vascular reactivity after inferior canine hindlimb ischemia/reperfusion: effects of in vivo nitric oxide blocker infusion.
    Annals of vascular surgery, 2007, Volume: 21, Issue:5

    Topics: Animals; Cyclooxygenase Inhibitors; Dogs; Endothelium-Dependent Relaxing Factors; Endothelium, Vascu

2007
Inhibition of inducible nitric oxide synthase ameliorates lung injury in rats after gut ischemia-reperfusion.
    The Journal of trauma, 2007, Volume: 63, Issue:3

    Topics: Analysis of Variance; Animals; Bacterial Translocation; Chi-Square Distribution; Guanidines; Intesti

2007
Intestinal diamine oxidase and histamine release in rabbit mesenteric ischemia.
    Gastroenterology, 1981, Volume: 80, Issue:5 pt 1

    Topics: Amine Oxidase (Copper-Containing); Animals; Dose-Response Relationship, Drug; Female; Guanidines; Hi

1981
Increased nitric oxide synthase activity despite lack of response to endothelium-dependent vasodilators in postischemic acute renal failure in rats.
    The Journal of clinical investigation, 1995, Volume: 96, Issue:1

    Topics: Acetylcholine; Acute Kidney Injury; Amino Acid Oxidoreductases; Animals; Arginine; Endothelium, Vasc

1995
Nitric oxide synthase inhibitors protect rat retina against ischemic injury.
    FEBS letters, 1995, Nov-06, Volume: 374, Issue:3

    Topics: Animals; Arginine; Cell Count; Enzyme Inhibitors; Guanidines; Intraocular Pressure; Ischemia; Male;

1995
Role of histamine in the intestinal flow response following mesenteric ischemia.
    Shock (Augusta, Ga.), 1994, Volume: 2, Issue:6

    Topics: Animals; Blood Flow Velocity; Cimetidine; Cromolyn Sodium; Dogs; Female; Guanidines; Histamine; Ileu

1994
The influence of skin flap ischemia on serum nitric oxide concentrations.
    Microsurgery, 1996, Volume: 17, Issue:4

    Topics: Animals; Cyclic GMP; Enzyme Inhibitors; Guanidines; Heparin; Ischemia; Male; NG-Nitroarginine Methyl

1996
Physiological roles of endothelium-derived nitric oxide in the epigastric island flaps of rabbits.
    Annals of plastic surgery, 1997, Volume: 39, Issue:6

    Topics: Animals; Cyclic GMP; Endothelium, Vascular; Epigastric Arteries; Guanidines; Heparin; Ischemia; Male

1997
Ischemic tolerance in skeletal muscle: role of nitric oxide.
    The American journal of physiology, 1998, Volume: 275, Issue:1

    Topics: Animals; Enzyme Inhibitors; Guanidines; Ischemia; Ischemic Preconditioning; Kinetics; Male; Microcir

1998
Neutrophil sequestration in the lung following acute aortic occlusion starts during ischaemia and can be attenuated by tumour necrosis factor and nitric oxide blockade.
    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 1998, Volume: 16, Issue:1

    Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents; Aorta; Chemotaxis; Constriction; Dexamethas

1998
Selective inhibition of inducible nitric oxide in ischemia-reperfusion of rat small intestine.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 2000, Volume: 99, Issue:3

    Topics: Animals; Arginine; Blood Pressure; CD11 Antigens; Enzyme Inhibitors; Guanidines; Intestine, Small; I

2000
Histaminergic effect on apoptosis of rat small intestinal mucosa after ischemia-reperfusion.
    Digestive diseases and sciences, 2000, Volume: 45, Issue:6

    Topics: Animals; Apoptosis; Chlorpheniramine; Cimetidine; Guanidines; Histamine; Histamine Antagonists; Inte

2000
Intestinal ischemia induces late preconditioning against myocardial infarction: a role for inducible nitric oxide synthase.
    Cardiovascular research, 2001, Feb-01, Volume: 49, Issue:2

    Topics: Analysis of Variance; Animals; Enzyme Inhibitors; Guanidines; Intestinal Mucosa; Intestines; Ischemi

2001
Hemodynamic, biochemical and morphological changes induced by aminoguanidine in normal and septic sheep.
    Intensive care medicine, 2000, Volume: 26, Issue:11

    Topics: Acidosis; Analysis of Variance; Animals; Blood Pressure; Case-Control Studies; Enzyme Inhibitors; Gu

2000
Long-term observations on the reversibility of cochlear dysfunction after transient ischemia.
    Hearing research, 2002, Volume: 166, Issue:1-2

    Topics: Animals; Cochlea; Enzyme Inhibitors; Evoked Potentials, Auditory, Brain Stem; Guanidines; Guinea Pig

2002
Diamine oxidase activity and histamine release in dogs following acute mesenteric artery occlusion.
    Agents and actions, 1977, Volume: 7, Issue:1

    Topics: Amine Oxidase (Copper-Containing); Animals; Dogs; Guanidines; Histamine; Histamine Release; Intestin

1977
Studies on the relationship between xanthine oxidase and histamine release during intestinal ischemia-reperfusion.
    Circulatory shock, 1992, Volume: 38, Issue:2

    Topics: Animals; Cromolyn Sodium; Disease Models, Animal; Dogs; Female; Guanidines; Histamine; Histamine Rel

1992