pimagedine has been researched along with Ischemia in 24 studies
pimagedine: diamine oxidase & nitric oxide synthase inhibitor; an advanced glycosylation end product inhibitor; used in the treatment of diabetic complications; structure
aminoguanidine : A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.
Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study aimed to examine the relationship between a harmful effect of histamine and apoptosis following ischemia-reperfusion in the rat intestine." | 7.70 | Histaminergic effect on apoptosis of rat small intestinal mucosa after ischemia-reperfusion. ( Fujimoto, K; Fukuyama, K; Iwakiri, R; Kojima, M; Noda, T; Okamoto, K; Yoshida, T, 2000) |
| "Recent studies have demonstrated a connection between xanthine oxidase-generated reactive oxygen intermediates and histamine release during ischemia-reperfusion." | 7.68 | Studies on the relationship between xanthine oxidase and histamine release during intestinal ischemia-reperfusion. ( Bakó, L; Boros, M; Kaszaki, J; Nagy, S, 1992) |
| " A monoexponential dose-response relationship was found between the specific diamine oxidase inhibitor aminoguanidine and reduced survival time." | 5.26 | Intestinal diamine oxidase and histamine release in rabbit mesenteric ischemia. ( Hesterberg, R; Hinterlang, E; Kusche, J; Lorenz, W; Ohmann, C; Richter, H; Schmal, A; Stahlknecht, CD; Weber, D, 1981) |
| " Our study was designed to investigate the involvement of MMPs and of tissue inhibitors of metalloproteinases (TIMPs) in rat retinal ischemic injury, the effect of nitric oxide synthase (NOS) inhibitors on MMPs' activity in this model and whether minocycline (an MMP inhibitor) is protective in retinal ischemia." | 3.74 | The involvement of matrix metalloproteinases 2 and 9 in rat retinal ischemia. ( Bahar-Shany, K; Geyer, O; Lahat, N; Mathalone, N; Oron, Y; Rahat, MA, 2007) |
| "This study aimed to examine the relationship between a harmful effect of histamine and apoptosis following ischemia-reperfusion in the rat intestine." | 3.70 | Histaminergic effect on apoptosis of rat small intestinal mucosa after ischemia-reperfusion. ( Fujimoto, K; Fukuyama, K; Iwakiri, R; Kojima, M; Noda, T; Okamoto, K; Yoshida, T, 2000) |
| "Recent studies have demonstrated a connection between xanthine oxidase-generated reactive oxygen intermediates and histamine release during ischemia-reperfusion." | 3.68 | Studies on the relationship between xanthine oxidase and histamine release during intestinal ischemia-reperfusion. ( Bakó, L; Boros, M; Kaszaki, J; Nagy, S, 1992) |
| "Brief ischemia was reported to protect retinal cells against injury induced by subsequent ischemia-reperfusion with de novo protein synthesis, and this phenomenon is known as late ischemic preconditioning." | 1.33 | Inducible nitric oxide synthase inhibitors abolished histological protection by late ischemic preconditioning in rat retina. ( Ishii, K; Kubota, Y; Kuwagata, M; Nakahara, T; Saito, M; Sakamoto, K; Yonoki, Y, 2006) |
| "After 8 weeks of treatment, hindlimb ischemia was induced by right femoral artery ligature." | 1.32 | Blockade of advanced glycation end-product formation restores ischemia-induced angiogenesis in diabetic mice. ( Benessiano, J; Duriez, M; Ebrahimian, TG; Huijberts, M; Lévy, BI; Silvestre, JS; Tamarat, R; Wautier, JL; Wautier, MP, 2003) |
| "Sepsis was induced by the intravenous administration of E." | 1.31 | Hemodynamic, biochemical and morphological changes induced by aminoguanidine in normal and septic sheep. ( Delgado, MA; Esteban, A; Fernández-Segoviano, P; Jara, N; Lorente, JA; Moscoso, A; Rodríguez-Corcos, A; Tejedor, C; Tobalina, R, 2000) |
| " A monoexponential dose-response relationship was found between the specific diamine oxidase inhibitor aminoguanidine and reduced survival time." | 1.26 | Intestinal diamine oxidase and histamine release in rabbit mesenteric ischemia. ( Hesterberg, R; Hinterlang, E; Kusche, J; Lorenz, W; Ohmann, C; Richter, H; Schmal, A; Stahlknecht, CD; Weber, D, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (8.33) | 18.7374 |
| 1990's | 8 (33.33) | 18.2507 |
| 2000's | 12 (50.00) | 29.6817 |
| 2010's | 2 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shin, JK | 1 |
| Kang, JW | 1 |
| Lee, SM | 1 |
| Takizawa, Y | 1 |
| Kitazato, T | 1 |
| Ishizaka, H | 1 |
| Kamiya, N | 1 |
| Tomita, M | 1 |
| Hayashi, M | 1 |
| Neufeld, AH | 1 |
| Kawai, Si | 1 |
| Das, S | 1 |
| Vora, S | 1 |
| Gachie, E | 1 |
| Connor, JR | 1 |
| Manning, PT | 1 |
| Badhwar, A | 1 |
| Dungey, AA | 1 |
| Harris, KA | 2 |
| Scott, JA | 2 |
| McCarter, SD | 1 |
| Scott, JR | 1 |
| Forbes, TL | 1 |
| Potter, RF | 2 |
| Tamarat, R | 1 |
| Silvestre, JS | 1 |
| Huijberts, M | 1 |
| Benessiano, J | 1 |
| Ebrahimian, TG | 1 |
| Duriez, M | 1 |
| Wautier, MP | 1 |
| Wautier, JL | 1 |
| Lévy, BI | 1 |
| Sakamoto, K | 1 |
| Yonoki, Y | 1 |
| Kubota, Y | 1 |
| Kuwagata, M | 1 |
| Saito, M | 1 |
| Nakahara, T | 1 |
| Ishii, K | 1 |
| Mathalone, N | 1 |
| Lahat, N | 1 |
| Rahat, MA | 1 |
| Bahar-Shany, K | 1 |
| Oron, Y | 2 |
| Geyer, O | 2 |
| Joviliano, EE | 1 |
| Piccinato, CE | 1 |
| Cherri, J | 1 |
| Viaro, F | 1 |
| Moryia, T | 1 |
| Celotto, AC | 1 |
| Bonaventura, D | 1 |
| Evora, PR | 1 |
| Uchida, K | 1 |
| Mishima, S | 1 |
| Ohta, S | 1 |
| Yukioka, T | 1 |
| Kusche, J | 2 |
| Lorenz, W | 2 |
| Stahlknecht, CD | 2 |
| Richter, H | 2 |
| Hesterberg, R | 1 |
| Schmal, A | 1 |
| Hinterlang, E | 1 |
| Weber, D | 1 |
| Ohmann, C | 1 |
| Conger, J | 1 |
| Robinette, J | 1 |
| Villar, A | 1 |
| Raij, L | 1 |
| Shultz, P | 1 |
| Almog, J | 1 |
| Lupu-Meiri, M | 1 |
| Lazar, M | 1 |
| Kaszaki, J | 2 |
| Boros, M | 2 |
| Szabó, A | 1 |
| Nagy, S | 2 |
| Oshima, H | 2 |
| Inoue, H | 1 |
| Aihara, M | 1 |
| Tomioka, M | 1 |
| Ishida, H | 1 |
| Pudupakkam, S | 1 |
| Jamieson, WG | 1 |
| DeRose, G | 1 |
| Carson, MW | 1 |
| Schlag, MG | 1 |
| Kvietys, PR | 1 |
| Tassiopoulos, AK | 1 |
| Hakim, TS | 1 |
| Finck, CM | 1 |
| Pedoto, A | 1 |
| Hodell, MG | 1 |
| Landas, SK | 1 |
| McGraw, DJ | 1 |
| Chen, JC | 1 |
| Chen, HM | 1 |
| Shyr, MH | 1 |
| Fan, LL | 1 |
| Chi, TY | 1 |
| Chi, CP | 1 |
| Chen, MF | 1 |
| Yoshida, T | 1 |
| Iwakiri, R | 1 |
| Noda, T | 1 |
| Okamoto, K | 1 |
| Kojima, M | 1 |
| Fukuyama, K | 1 |
| Fujimoto, K | 1 |
| Wang, Y | 1 |
| Xu, H | 1 |
| Mizoguchi, K | 1 |
| Oe, M | 1 |
| Maeta, H | 1 |
| Lorente, JA | 1 |
| Tejedor, C | 1 |
| Delgado, MA | 1 |
| Fernández-Segoviano, P | 1 |
| Jara, N | 1 |
| Tobalina, R | 1 |
| Rodríguez-Corcos, A | 1 |
| Moscoso, A | 1 |
| Esteban, A | 1 |
| Tsuji, S | 1 |
| Tabuchi, K | 1 |
| Hara, A | 1 |
| Kusakari, J | 1 |
| Reichert, G | 1 |
| Bakó, L | 1 |
24 other studies available for pimagedine and Ischemia
| Article | Year |
|---|---|
Enhanced nitric oxide-mediated autophagy contributes to the hepatoprotective effects of ischemic preconditioning during ischemia and reperfusion.
Topics: Animals; Autophagy; Chloroquine; Guanidines; Imidazoles; Ischemia; Ischemic Preconditioning; Liver; | 2016 |
Effect of aminoguanidine on ischemia/reperfusion injury in rat small intestine.
Topics: Animals; Area Under Curve; Enzyme Inhibitors; Guanidines; Intestine, Small; Ischemia; Male; Nitric O | 2011 |
Loss of retinal ganglion cells following retinal ischemia: the role of inducible nitric oxide synthase.
Topics: Animals; Enzyme Inhibitors; Guanidines; Homoarginine; Ischemia; Male; Necrosis; Neutrophils; Nitric | 2002 |
Limitations of ischemic tolerance in oxidative skeletal muscle: perfusion vs tissue protection.
Topics: Animals; Calcium; Enzyme Inhibitors; Guanidines; Ischemia; Ischemic Preconditioning; Male; Microcirc | 2003 |
Blockade of advanced glycation end-product formation restores ischemia-induced angiogenesis in diabetic mice.
Topics: Angiography; Animals; Collagen; Collagenases; Collateral Circulation; Diabetes Mellitus, Experimenta | 2003 |
Inducible nitric oxide synthase inhibitors abolished histological protection by late ischemic preconditioning in rat retina.
Topics: Animals; Enzyme Inhibitors; Guanidines; Indazoles; Ischemia; Ischemic Preconditioning; Lysine; Male; | 2006 |
The involvement of matrix metalloproteinases 2 and 9 in rat retinal ischemia.
Topics: Animals; Blotting, Western; Disease Models, Animal; Enzyme Inhibitors; Guanidines; Ischemia; Male; M | 2007 |
In vitro pharmacological study of femoral artery vascular reactivity after inferior canine hindlimb ischemia/reperfusion: effects of in vivo nitric oxide blocker infusion.
Topics: Animals; Cyclooxygenase Inhibitors; Dogs; Endothelium-Dependent Relaxing Factors; Endothelium, Vascu | 2007 |
Inhibition of inducible nitric oxide synthase ameliorates lung injury in rats after gut ischemia-reperfusion.
Topics: Analysis of Variance; Animals; Bacterial Translocation; Chi-Square Distribution; Guanidines; Intesti | 2007 |
Intestinal diamine oxidase and histamine release in rabbit mesenteric ischemia.
Topics: Amine Oxidase (Copper-Containing); Animals; Dose-Response Relationship, Drug; Female; Guanidines; Hi | 1981 |
Increased nitric oxide synthase activity despite lack of response to endothelium-dependent vasodilators in postischemic acute renal failure in rats.
Topics: Acetylcholine; Acute Kidney Injury; Amino Acid Oxidoreductases; Animals; Arginine; Endothelium, Vasc | 1995 |
Nitric oxide synthase inhibitors protect rat retina against ischemic injury.
Topics: Animals; Arginine; Cell Count; Enzyme Inhibitors; Guanidines; Intraocular Pressure; Ischemia; Male; | 1995 |
Role of histamine in the intestinal flow response following mesenteric ischemia.
Topics: Animals; Blood Flow Velocity; Cimetidine; Cromolyn Sodium; Dogs; Female; Guanidines; Histamine; Ileu | 1994 |
The influence of skin flap ischemia on serum nitric oxide concentrations.
Topics: Animals; Cyclic GMP; Enzyme Inhibitors; Guanidines; Heparin; Ischemia; Male; NG-Nitroarginine Methyl | 1996 |
Physiological roles of endothelium-derived nitric oxide in the epigastric island flaps of rabbits.
Topics: Animals; Cyclic GMP; Endothelium, Vascular; Epigastric Arteries; Guanidines; Heparin; Ischemia; Male | 1997 |
Ischemic tolerance in skeletal muscle: role of nitric oxide.
Topics: Animals; Enzyme Inhibitors; Guanidines; Ischemia; Ischemic Preconditioning; Kinetics; Male; Microcir | 1998 |
Neutrophil sequestration in the lung following acute aortic occlusion starts during ischaemia and can be attenuated by tumour necrosis factor and nitric oxide blockade.
Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents; Aorta; Chemotaxis; Constriction; Dexamethas | 1998 |
Selective inhibition of inducible nitric oxide in ischemia-reperfusion of rat small intestine.
Topics: Animals; Arginine; Blood Pressure; CD11 Antigens; Enzyme Inhibitors; Guanidines; Intestine, Small; I | 2000 |
Histaminergic effect on apoptosis of rat small intestinal mucosa after ischemia-reperfusion.
Topics: Animals; Apoptosis; Chlorpheniramine; Cimetidine; Guanidines; Histamine; Histamine Antagonists; Inte | 2000 |
Intestinal ischemia induces late preconditioning against myocardial infarction: a role for inducible nitric oxide synthase.
Topics: Analysis of Variance; Animals; Enzyme Inhibitors; Guanidines; Intestinal Mucosa; Intestines; Ischemi | 2001 |
Hemodynamic, biochemical and morphological changes induced by aminoguanidine in normal and septic sheep.
Topics: Acidosis; Analysis of Variance; Animals; Blood Pressure; Case-Control Studies; Enzyme Inhibitors; Gu | 2000 |
Long-term observations on the reversibility of cochlear dysfunction after transient ischemia.
Topics: Animals; Cochlea; Enzyme Inhibitors; Evoked Potentials, Auditory, Brain Stem; Guanidines; Guinea Pig | 2002 |
Diamine oxidase activity and histamine release in dogs following acute mesenteric artery occlusion.
Topics: Amine Oxidase (Copper-Containing); Animals; Dogs; Guanidines; Histamine; Histamine Release; Intestin | 1977 |
Studies on the relationship between xanthine oxidase and histamine release during intestinal ischemia-reperfusion.
Topics: Animals; Cromolyn Sodium; Disease Models, Animal; Dogs; Female; Guanidines; Histamine; Histamine Rel | 1992 |