pimagedine has been researched along with Insulin Sensitivity in 7 studies
pimagedine: diamine oxidase & nitric oxide synthase inhibitor; an advanced glycosylation end product inhibitor; used in the treatment of diabetic complications; structure
aminoguanidine : A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The AMP-activated protein kinase (AMPK) activator metformin reverses obesity-associated insulin resistance (IR) and inhibits different types of inflammatory responses." | 7.79 | Metformin attenuates the exacerbation of the allergic eosinophilic inflammation in high fat-diet-induced obesity in mice. ( André, DM; Anhê, GF; Antunes, E; Bordin, S; Calixto, MC; Ferreira, D; Landgraf, RG; Leiria, LO; Lellis-Santos, C; Lintomen, L, 2013) |
| " The AMP-activated protein kinase (AMPK) activator metformin reverses obesity-associated insulin resistance (IR) and inhibits different types of inflammatory responses." | 3.79 | Metformin attenuates the exacerbation of the allergic eosinophilic inflammation in high fat-diet-induced obesity in mice. ( André, DM; Anhê, GF; Antunes, E; Bordin, S; Calixto, MC; Ferreira, D; Landgraf, RG; Leiria, LO; Lellis-Santos, C; Lintomen, L, 2013) |
| "Insulin sensitivity was measured using the insulin tolerance test (ITT), both in STZ diabetic and in Zucker diabetic fatty (ZDF) rats (model of type 2 diabetes)." | 1.31 | Effect of BRX-220 against peripheral neuropathy and insulin resistance in diabetic rat models. ( Bíró, K; Jednákovits, A; Kukorelli, T; Kürthy, M; Mogyorósi, T; Nagy, K; Tálosi, L, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Radika, MK | 1 |
| Viswanathan, P | 1 |
| Anuradha, CV | 1 |
| Calixto, MC | 1 |
| Lintomen, L | 1 |
| André, DM | 1 |
| Leiria, LO | 1 |
| Ferreira, D | 1 |
| Lellis-Santos, C | 1 |
| Anhê, GF | 1 |
| Bordin, S | 1 |
| Landgraf, RG | 1 |
| Antunes, E | 1 |
| Serino, M | 1 |
| Waget, A | 1 |
| Marsollier, N | 1 |
| Masseboeuf, M | 1 |
| Payros, G | 1 |
| Kabani, C | 1 |
| Denom, J | 1 |
| Lacombe, A | 1 |
| Thiers, JC | 1 |
| Negre-Salvayre, A | 1 |
| Luquet, S | 1 |
| Burcelin, R | 1 |
| Cruciani-Guglielmacci, C | 1 |
| Magnan, C | 1 |
| Kwon, G | 1 |
| Xu, G | 1 |
| Marshall, CA | 1 |
| McDaniel, ML | 1 |
| Ohta, M | 1 |
| Sugita, H | 1 |
| Kaneki, M | 1 |
| Tokunaga, E | 1 |
| Sugita, M | 1 |
| Koike, C | 1 |
| Yasuhara, S | 1 |
| Tompkins, RG | 1 |
| Martyn, JA | 1 |
| Kürthy, M | 1 |
| Mogyorósi, T | 1 |
| Nagy, K | 1 |
| Kukorelli, T | 1 |
| Jednákovits, A | 1 |
| Tálosi, L | 1 |
| Bíró, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Multicenter, Dose Ranging Safety and Pharmacokinetics Study of Arimoclomol in Amyotrophic Lateral Sclerosis (ALS)[NCT00244244] | Phase 2 | 80 participants | Interventional | 2005-10-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for pimagedine and Insulin Sensitivity
| Article | Year |
|---|---|
[Current advances in the treatment of diabetes mellitus].
Topics: Aldehyde Reductase; Arteriosclerosis; Blood Glucose; Diabetes Mellitus; Enzyme Inhibitors; Guanidine | 1999 |
6 other studies available for pimagedine and Insulin Sensitivity
| Article | Year |
|---|---|
Nitric oxide mediates the insulin sensitizing effects of β-sitosterol in high fat diet-fed rats.
Topics: Analysis of Variance; Animals; Blood Glucose; Body Weight; Diet, High-Fat; Guanidines; Hepatocytes; | 2013 |
Metformin attenuates the exacerbation of the allergic eosinophilic inflammation in high fat-diet-induced obesity in mice.
Topics: AMP-Activated Protein Kinases; Animals; Asthma; Blotting, Western; Bronchoalveolar Lavage Fluid; Die | 2013 |
Lipid-induced peroxidation in the intestine is involved in glucose homeostasis imbalance in mice.
Topics: Animals; Glucose; Guanidines; Homeostasis; Insulin Resistance; Intestinal Mucosa; Intestines; Lipid | 2011 |
Tumor necrosis factor alpha-induced pancreatic beta-cell insulin resistance is mediated by nitric oxide and prevented by 15-deoxy-Delta12,14-prostaglandin J2 and aminoguanidine. A role for peroxisome proliferator-activated receptor gamma activation and in
Topics: Animals; Chromans; Guanidines; Hypoglycemic Agents; Insulin Resistance; Islets of Langerhans; Male; | 1999 |
Inducible nitric oxide synthase plays a role in LPS-induced hyperglycemia and insulin resistance.
Topics: Animals; Enzyme Induction; Enzyme Inhibitors; Glucose; Glycogen Phosphorylase; Guanidines; Hyperglyc | 2002 |
Effect of BRX-220 against peripheral neuropathy and insulin resistance in diabetic rat models.
Topics: Animals; Diabetic Neuropathies; Guanidines; Hydroxylamines; Hypoglycemic Agents; Insulin Resistance; | 2002 |