pimagedine has been researched along with Injuries, Spinal Cord in 10 studies
pimagedine: diamine oxidase & nitric oxide synthase inhibitor; an advanced glycosylation end product inhibitor; used in the treatment of diabetic complications; structure
aminoguanidine : A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The optimal dosage of AG was screened by dry-wet weight method with the percentage of water content at 0, 12, 24, and 48 hours after injury." | 1.38 | [Effect of aminoguanidine on spinal cord edema of acute spinal cord injury in rats]. ( Cao, Y; Fan, Z; Lü, G; Mei, X; Wang, Y; Yu, D; Zhang, M; Zhang, Z, 2012) |
| " Compared to SCI group without treatment, AG at the dosage of 150mg/kg induced a reduction in the permeability of blood-spinal cord barrier (BSCB) after injury 48h (from 59." | 1.36 | The effect of aminoguanidine on compression spinal cord injury in rats. ( Cao, Y; Fan, ZK; Lu, W; Lv, G; Wang, YF; Zhang, MC; Zhang, YQ; Zhang, Z, 2010) |
| "We studied the effects of inhibitors of COX-2 (NS398) and iNOS (aminoguanidine) alone or in combination with olfactory ensheathing cell (OEC) grafts after spinal cord injury in the rat." | 1.33 | Effects of COX-2 and iNOS inhibitors alone or in combination with olfactory ensheathing cell grafts after spinal cord injury. ( Casas, C; Forés, J; García-Alías, G; Guzmán-Lenis, MS; López-Vales, R; Navarro, X; Verdú, E, 2006) |
| "The secondary injury process following spinal cord trauma has been shown to involve different mechanisms such as excessive release of excitatory amino-acids, and induction of free radical induced lipid peroxidation." | 1.32 | Time-level relationship for nitric oxide and the protective effects of aminoguanidine in experimental spinal cord injury. ( Aslan, O; Barut, S; Belce, A; Colak, A; Iğdem, AA; Soy, O; Uzun, H, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (70.00) | 29.6817 |
| 2010's | 3 (30.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, MY | 1 |
| Chen, L | 1 |
| Toborek, M | 1 |
| Xu, WB | 1 |
| Lv, G | 2 |
| Wang, YF | 2 |
| Lu, XH | 1 |
| Huang, T | 1 |
| Zhu, Y | 1 |
| Jia, LS | 1 |
| Fan, ZK | 1 |
| Cao, Y | 2 |
| Zhang, MC | 1 |
| Zhang, Z | 2 |
| Lu, W | 1 |
| Zhang, YQ | 1 |
| Maggio, DM | 1 |
| Chatzipanteli, K | 3 |
| Masters, N | 1 |
| Patel, SP | 1 |
| Dietrich, WD | 3 |
| Pearse, DD | 2 |
| Fan, Z | 1 |
| Wang, Y | 1 |
| Yu, D | 1 |
| Zhang, M | 1 |
| Mei, X | 1 |
| Lü, G | 1 |
| Zhang, XY | 1 |
| Zhou, CS | 1 |
| Jin, AM | 1 |
| Tian, J | 1 |
| Zhang, H | 1 |
| Yao, WT | 1 |
| Zheng, G | 1 |
| Marcillo, AE | 2 |
| Bunge, MB | 1 |
| Soy, O | 1 |
| Aslan, O | 1 |
| Uzun, H | 1 |
| Barut, S | 1 |
| Iğdem, AA | 1 |
| Belce, A | 1 |
| Colak, A | 1 |
| López-Vales, R | 1 |
| García-Alías, G | 1 |
| Guzmán-Lenis, MS | 1 |
| Forés, J | 1 |
| Casas, C | 1 |
| Navarro, X | 1 |
| Verdú, E | 1 |
| Garcia, R | 1 |
| Loor, KE | 1 |
| Kraydieh, S | 1 |
10 other studies available for pimagedine and Injuries, Spinal Cord
| Article | Year |
|---|---|
Nicotine attenuates iNOS expression and contributes to neuroprotection in a compressive model of spinal cord injury.
Topics: Animals; Disease Models, Animal; Enzyme Inhibitors; Guanidines; Injections, Intraperitoneal; Male; M | 2009 |
Combination of dexamethasone and aminoguanidine reduces secondary damage in compression spinal cord injury.
Topics: Animals; bcl-2-Associated X Protein; Blotting, Western; Body Fluids; Dexamethasone; Drug Therapy, Co | 2009 |
The effect of aminoguanidine on compression spinal cord injury in rats.
Topics: Animals; Antioxidants; Edema; Guanidines; Male; Neuroprotective Agents; Oxidative Stress; Rats; Rats | 2010 |
Acute molecular perturbation of inducible nitric oxide synthase with an antisense approach enhances neuronal preservation and functional recovery after contusive spinal cord injury.
Topics: Amidines; Animals; Benzylamines; Blood-Brain Barrier; Contusions; Enzyme Inhibitors; Female; Guanidi | 2012 |
[Effect of aminoguanidine on spinal cord edema of acute spinal cord injury in rats].
Topics: Acute Disease; Animals; Aquaporin 4; Blood-Brain Barrier; Blotting, Western; Disease Models, Animal; | 2012 |
Effect of aminoguanidine on the recovery of rat hindlimb motor function after spinal cord injury.
Topics: Animals; Apoptosis; Evoked Potentials, Motor; Guanidines; Hindlimb; Male; Nitric Oxide; Nitric Oxide | 2003 |
Comparison of iNOS inhibition by antisense and pharmacological inhibitors after spinal cord injury.
Topics: Amidines; Animals; Annexins; Astrocytes; Benzylamines; Blood-Brain Barrier; Cell Count; Cell Death; | 2003 |
Time-level relationship for nitric oxide and the protective effects of aminoguanidine in experimental spinal cord injury.
Topics: Animals; Disease Models, Animal; Guanidines; Lipid Peroxidation; Male; Motor Activity; Neuroprotecti | 2004 |
Effects of COX-2 and iNOS inhibitors alone or in combination with olfactory ensheathing cell grafts after spinal cord injury.
Topics: Animals; Brain Tissue Transplantation; Cell Transplantation; Cyclooxygenase 2 Inhibitors; Disease Mo | 2006 |
Temporal and segmental distribution of constitutive and inducible nitric oxide synthases after traumatic spinal cord injury: effect of aminoguanidine treatment.
Topics: Animals; Enzyme Inhibitors; Female; Guanidines; Immunohistochemistry; Nitric Oxide; Nitric Oxide Syn | 2002 |