pimagedine has been researched along with Inflammation in 49 studies
pimagedine: diamine oxidase & nitric oxide synthase inhibitor; an advanced glycosylation end product inhibitor; used in the treatment of diabetic complications; structure
aminoguanidine : A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The aim of the present study was to investigate the potential protective effect of l-arginine (Arg; nitric oxide precursor) and aminoguanidine (inducible nitric oxide synthase inhibitor) against acetic acid (AA)-induced colitis in rats, and the potential role of NF-κB." | 7.80 | L-arginine and aminoguanidine reduce colonic damage of acetic acid-induced colitis in rats: potential modulation of nuclear factor-κB/p65. ( Farghaly, HS; Thabit, RH, 2014) |
| " The AMP-activated protein kinase (AMPK) activator metformin reverses obesity-associated insulin resistance (IR) and inhibits different types of inflammatory responses." | 7.79 | Metformin attenuates the exacerbation of the allergic eosinophilic inflammation in high fat-diet-induced obesity in mice. ( André, DM; Anhê, GF; Antunes, E; Bordin, S; Calixto, MC; Ferreira, D; Landgraf, RG; Leiria, LO; Lellis-Santos, C; Lintomen, L, 2013) |
| " Diclofenac significantly reduced the carrageenan-induced edema in rat paw at all the time points studied." | 7.72 | Potentiation of diclofenac-induced anti-inflammatory response by aminoguanidine in carrageenan-induced acute inflammation in rats: the role of nitric oxide. ( Al-Majed, AA; Al-Shabanah, OA; Khattab, M; Mostafa, AM; Raza, M, 2003) |
| "However, meningitis-induced CSF leukocytosis at 4 h and increased CSF lactate and tumor necrosis factor alpha levels were not significantly attenuated." | 5.31 | 7-Nitroindazole, but not aminoguanidine, attenuates the acute inflammatory responses and brain injury during the early phase of Escherichia coli meningitis in the newborn piglet. ( Chang, YS; Lee, M; Park, WS, 2001) |
| " Obesity was induced by the administration of 4 mg/g body weight of monosodium glutamate (MSG) or equimolar saline (CTR) in newborn rats." | 3.85 | iNOS inhibition improves autonomic dysfunction and oxidative status in hypertensive obese rats. ( Cecchini, R; da Cunha, NV; Lopes, FN; Martins-Pinge, MC; Panis, C; Pinge-Filho, P, 2017) |
| " The aim of the present study was to investigate the potential protective effect of l-arginine (Arg; nitric oxide precursor) and aminoguanidine (inducible nitric oxide synthase inhibitor) against acetic acid (AA)-induced colitis in rats, and the potential role of NF-κB." | 3.80 | L-arginine and aminoguanidine reduce colonic damage of acetic acid-induced colitis in rats: potential modulation of nuclear factor-κB/p65. ( Farghaly, HS; Thabit, RH, 2014) |
| " The AMP-activated protein kinase (AMPK) activator metformin reverses obesity-associated insulin resistance (IR) and inhibits different types of inflammatory responses." | 3.79 | Metformin attenuates the exacerbation of the allergic eosinophilic inflammation in high fat-diet-induced obesity in mice. ( André, DM; Anhê, GF; Antunes, E; Bordin, S; Calixto, MC; Ferreira, D; Landgraf, RG; Leiria, LO; Lellis-Santos, C; Lintomen, L, 2013) |
| "We have reported that thyroid capsular thickening with inflammation induced by an antithyroidal agent, sulfadimethoxine (SDM), might play a role in the development of invasive follicular carcinomas in rats initiated with N-bis(2-hydroxypropyl)nitrosamine (DHPN)." | 3.75 | Inhibitory effects of aminoguanidine on thyroid follicular carcinoma development in inflamed capsular regions of rats treated with sulfadimethoxine after N-bis(2-hydroxypropyl)nitrosamine-initiation. ( Cho, YM; Hasumura, M; Hirose, M; Imai, T; Nishikawa, A; Ota, Y; Takami, S, 2009) |
| " Diclofenac significantly reduced the carrageenan-induced edema in rat paw at all the time points studied." | 3.72 | Potentiation of diclofenac-induced anti-inflammatory response by aminoguanidine in carrageenan-induced acute inflammation in rats: the role of nitric oxide. ( Al-Majed, AA; Al-Shabanah, OA; Khattab, M; Mostafa, AM; Raza, M, 2003) |
| " Immediately thereafter, Evans blue dye was intravenously administered, and the mice injured with burns were sacrificed at various times." | 3.71 | Effects of nitric oxide synthase inhibitors on vascular hyperpermeability with thermal injury in mice. ( Aihara, M; Ando, K; Inoue, H; Kumagai, N; Matsuzaki , K; Wakisaka, N, 2001) |
| "Inflammation was assessed by measurement of NO and prostaglandin E2 (PGE2) levels and the lysosomal leakage of the enzyme N-acetyl-B-D-glucosaminidase (NAG) into the exudate of the granuloma pouch 4 h after carrageenan injection." | 1.31 | Modulation of nitric oxide synthesis in inflammation. Relationship to oxygen-derived free radicals and prostaglandin synthesis. ( Gad, MZ; Khattab, M, 2000) |
| "However, meningitis-induced CSF leukocytosis at 4 h and increased CSF lactate and tumor necrosis factor alpha levels were not significantly attenuated." | 1.31 | 7-Nitroindazole, but not aminoguanidine, attenuates the acute inflammatory responses and brain injury during the early phase of Escherichia coli meningitis in the newborn piglet. ( Chang, YS; Lee, M; Park, WS, 2001) |
| "GI inflammation is associated with an increase in nitric oxide production and expression of the inducible isoform of nitric oxide synthase (iNOS)." | 1.30 | The effect of inhibitors of inducible nitric oxide synthase on chronic colitis in the rhesus monkey. ( Allen, PC; Clark, DA; Connor, JR; Currie, MG; Didier, P; Manning, PT; Miller, MJ; Ratterree, MS; Ribbons, KA, 1997) |
| " TNFalpha was the most sensitive to thalidomide, showing dose-response inhibition at concentrations of 20 microg/ml, 50 microg/ml and 250 microg/ml." | 1.30 | Mycoplasma fermentans-induced inflammatory response of astrocytes: selective modulation by aminoguanidine, thalidomide, pentoxifylline and IL-10. ( Brenner, T; Gallily, R; Kipper-Galperin, M, 1999) |
| "Acute inflammation was associated with enlarged colonic perimeter." | 1.29 | Toxic dilatation of colon in a rat model of colitis is linked to an inducible form of nitric oxide synthase. ( Guarner, F; Malagelada, JR; Mourelle, M; Salas, A; Vilaseca, J, 1996) |
| "3 Paw oedema was maximal by 6 h and remained elevated for 10 h following carrageenan administration." | 1.29 | Nitric oxide: a key mediator in the early and late phase of carrageenan-induced rat paw inflammation. ( Bourdon, DM; Currie, MG; Manning, PT; Marino, MH; Salvemini, D; Wang, ZQ; Wyatt, PS, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 13 (26.53) | 18.2507 |
| 2000's | 16 (32.65) | 29.6817 |
| 2010's | 15 (30.61) | 24.3611 |
| 2020's | 5 (10.20) | 2.80 |
| Authors | Studies |
|---|---|
| Rouger, C | 1 |
| Derbré, S | 1 |
| Charreau, B | 1 |
| Pabois, A | 1 |
| Cauchy, T | 1 |
| Litaudon, M | 1 |
| Awang, K | 1 |
| Richomme, P | 1 |
| Gomes, JAS | 1 |
| Silva, JF | 1 |
| Marçal, AP | 1 |
| Silva, GC | 1 |
| Gomes, GF | 1 |
| de Oliveira, ACP | 1 |
| Soares, VL | 1 |
| Oliveira, MC | 1 |
| Ferreira, AVM | 1 |
| Aguiar, DC | 1 |
| Beheshti, F | 2 |
| Hosseini, M | 2 |
| Hashemzehi, M | 2 |
| Hadipanah, MR | 1 |
| Mahmoudabady, M | 1 |
| Marefati, N | 1 |
| Memarpour, S | 1 |
| Prantner, D | 1 |
| Nallar, S | 1 |
| Richard, K | 1 |
| Spiegel, D | 1 |
| Collins, KD | 1 |
| Vogel, SN | 1 |
| Drygalski, K | 1 |
| Fereniec, E | 1 |
| Zalewska, A | 1 |
| Krętowski, A | 1 |
| Żendzian-Piotrowska, M | 1 |
| Maciejczyk, M | 1 |
| Morais, SRL | 1 |
| Brito, VGB | 1 |
| Mello, WG | 1 |
| Oliveira, SHP | 1 |
| Natarajan, K | 1 |
| Abraham, P | 1 |
| Kota, R | 1 |
| Isaac, B | 1 |
| de Brito, TV | 1 |
| Prudêncio, Rda S | 1 |
| Sales, AB | 1 |
| Vieira, Fd | 1 |
| Candeira, SJ | 1 |
| Franco, ÁX | 1 |
| Aragão, KS | 1 |
| Ribeiro, Rde A | 1 |
| Ponte de Souza, MH | 1 |
| Chaves, Lde S | 1 |
| Freitas, AL | 1 |
| Medeiros, JV | 1 |
| dos Reis Barbosa, AL | 1 |
| Tazawa, H | 1 |
| Kawaguchi, T | 1 |
| Kobayashi, T | 1 |
| Kuramitsu, Y | 1 |
| Wada, S | 1 |
| Satomi, Y | 1 |
| Nishino, H | 1 |
| Kobayashi, M | 1 |
| Kanda, Y | 1 |
| Osaki, M | 1 |
| Kitagawa, T | 1 |
| Hosokawa, M | 1 |
| Okada, F | 1 |
| Tian, M | 1 |
| Qing, C | 1 |
| Niu, Y | 1 |
| Dong, J | 1 |
| Cao, X | 1 |
| Song, F | 1 |
| Ji, X | 1 |
| Lu, S | 1 |
| Calixto, MC | 1 |
| Lintomen, L | 1 |
| André, DM | 1 |
| Leiria, LO | 1 |
| Ferreira, D | 1 |
| Lellis-Santos, C | 1 |
| Anhê, GF | 1 |
| Bordin, S | 1 |
| Landgraf, RG | 1 |
| Antunes, E | 1 |
| Chang, PC | 1 |
| Tsai, SC | 1 |
| Jheng, YH | 1 |
| Lin, YF | 1 |
| Chen, CC | 1 |
| Díaz, A | 1 |
| Rojas, K | 1 |
| Espinosa, B | 1 |
| Chávez, R | 1 |
| Zenteno, E | 1 |
| Limón, D | 1 |
| Guevara, J | 1 |
| Farghaly, HS | 1 |
| Thabit, RH | 1 |
| Wang, S | 1 |
| Li, B | 1 |
| Li, C | 1 |
| Cui, W | 1 |
| Miao, L | 1 |
| da Cunha, NV | 1 |
| Lopes, FN | 1 |
| Panis, C | 1 |
| Cecchini, R | 1 |
| Pinge-Filho, P | 1 |
| Martins-Pinge, MC | 1 |
| Imai, T | 1 |
| Hasumura, M | 1 |
| Cho, YM | 1 |
| Ota, Y | 1 |
| Takami, S | 1 |
| Hirose, M | 1 |
| Nishikawa, A | 1 |
| Semba, RD | 1 |
| Nicklett, EJ | 1 |
| Ferrucci, L | 1 |
| Cella, M | 2 |
| Farina, MG | 1 |
| Dominguez Rubio, AP | 1 |
| Di Girolamo, G | 1 |
| Ribeiro, ML | 1 |
| Franchi, AM | 1 |
| de Macchi, BM | 1 |
| Miranda, FJ | 1 |
| de Souza, FS | 1 |
| de Carvalho, EC | 1 |
| Albernaz, AP | 1 |
| do Nascimento, JL | 1 |
| DaMatta, RA | 1 |
| Al-Majed, AA | 1 |
| Khattab, M | 2 |
| Raza, M | 1 |
| Al-Shabanah, OA | 1 |
| Mostafa, AM | 1 |
| Dal Secco, D | 1 |
| Paron, JA | 1 |
| de Oliveira, SH | 1 |
| Ferreira, SH | 1 |
| Silva, JS | 1 |
| Cunha, Fde Q | 1 |
| Ribeiro, M | 1 |
| Farina, M | 1 |
| Franchi, A | 1 |
| Cavriani, G | 1 |
| Oliveira-Filho, RM | 1 |
| Trezena, AG | 1 |
| da Silva, ZL | 1 |
| Domingos, HV | 1 |
| de Arruda, MJ | 1 |
| Jancar, S | 1 |
| Tavares de Lima, W | 1 |
| Iravani, MM | 1 |
| Liu, L | 1 |
| Rose, S | 1 |
| Jenner, P | 1 |
| Sheu, ML | 1 |
| Chao, KF | 1 |
| Sung, YJ | 1 |
| Lin, WW | 1 |
| Lin-Shiau, SY | 1 |
| Liu, SH | 1 |
| Dudhgaonkar, SP | 1 |
| Tandan, SK | 1 |
| Bhat, AS | 1 |
| Jadhav, SH | 1 |
| Kumar, D | 1 |
| Heemskerk, S | 1 |
| van Koppen, A | 1 |
| van den Broek, L | 1 |
| Poelen, GJ | 1 |
| Wouterse, AC | 1 |
| Dijkman, HB | 1 |
| Russel, FG | 1 |
| Masereeuw, R | 1 |
| Kemna, EH | 1 |
| Pickkers, P | 1 |
| Tjalsma, H | 1 |
| Swinkels, DW | 1 |
| Salvemini, D | 2 |
| Seibert, K | 1 |
| Masferrer, JL | 1 |
| Settle, SL | 1 |
| Misko, TP | 1 |
| Currie, MG | 3 |
| Needleman, P | 1 |
| Mourelle, M | 1 |
| Vilaseca, J | 1 |
| Guarner, F | 1 |
| Salas, A | 1 |
| Malagelada, JR | 1 |
| Wang, ZQ | 1 |
| Wyatt, PS | 1 |
| Bourdon, DM | 1 |
| Marino, MH | 1 |
| Manning, PT | 2 |
| Ribbons, KA | 1 |
| Connor, JR | 1 |
| Allen, PC | 1 |
| Didier, P | 1 |
| Ratterree, MS | 1 |
| Clark, DA | 1 |
| Miller, MJ | 2 |
| Ridger, VC | 1 |
| Pettipher, ER | 1 |
| Bryant, CE | 1 |
| Brain, SD | 1 |
| Hsueh, W | 1 |
| Tan, XD | 1 |
| Qu, XW | 1 |
| Sun, XM | 1 |
| Gonzalez-Crussi, F | 1 |
| Oyama, Ji | 1 |
| Shimokawa, H | 1 |
| Momii, H | 1 |
| Cheng, X | 1 |
| Fukuyama, N | 1 |
| Arai, Y | 1 |
| Egashira, K | 1 |
| Nakazawa, H | 1 |
| Takeshita, A | 1 |
| MacNaughton, WK | 1 |
| Aurora, AR | 1 |
| Bhamra, J | 1 |
| Sharkey, KA | 1 |
| Tassiopoulos, AK | 1 |
| Hakim, TS | 1 |
| Finck, CM | 1 |
| Pedoto, A | 1 |
| Hodell, MG | 1 |
| Landas, SK | 1 |
| McGraw, DJ | 1 |
| Angstwurm, K | 1 |
| Freyer, D | 1 |
| Dirnagl, U | 1 |
| Hanisch, UK | 1 |
| Schumann, RR | 1 |
| Einhäupl, KM | 1 |
| Weber, JR | 1 |
| Shapiro, HK | 1 |
| Gallily, R | 1 |
| Kipper-Galperin, M | 1 |
| Brenner, T | 1 |
| Del Sero, G | 1 |
| Mencacci, A | 1 |
| Cenci, E | 1 |
| d'Ostiani, CF | 1 |
| Montagnoli, C | 1 |
| Bacci, A | 1 |
| Mosci, P | 1 |
| Kopf, M | 1 |
| Romani, L | 1 |
| Gad, MZ | 1 |
| Bossone, C | 1 |
| Hosseini, JM | 1 |
| Piñeiro-Carrero, V | 1 |
| Shea-Donohue, T | 1 |
| Park, WS | 1 |
| Chang, YS | 1 |
| Lee, M | 1 |
| Inoue, H | 1 |
| Ando, K | 1 |
| Wakisaka, N | 1 |
| Matsuzaki , K | 1 |
| Aihara, M | 1 |
| Kumagai, N | 1 |
| Omote, K | 1 |
| Hazama, K | 1 |
| Kawamata, T | 1 |
| Kawamata, M | 1 |
| Nakayaka, Y | 1 |
| Toriyabe, M | 1 |
| Namiki, A | 1 |
| Mohn, C | 1 |
| Lomniczi, A | 1 |
| Faletti, A | 1 |
| Scorticati, C | 1 |
| Elverdin, JC | 1 |
| McCann, SM | 1 |
| Rettori, V | 1 |
3 reviews available for pimagedine and Inflammation
| Article | Year |
|---|---|
Potential Renoprotective Agents through Inhibiting CTGF/CCN2 in Diabetic Nephropathy.
Topics: Animals; Anthocyanins; Antibodies, Monoclonal; Connective Tissue Growth Factor; Diabetes Mellitus; D | 2015 |
Does accumulation of advanced glycation end products contribute to the aging phenotype?
Topics: Aging; Bone and Bones; Brain; Diet; Enzyme Inhibitors; Erythrocytes; Eye; Food Analysis; Glycation E | 2010 |
Carbonyl-trapping therapeutic strategies.
Topics: Aldehydes; Alzheimer Disease; Amines; Animals; Carbohydrate Metabolism; Fatty Acids; Guanidines; Hum | 1998 |
2 trials available for pimagedine and Inflammation
| Article | Year |
|---|---|
Chickens treated with a nitric oxide inhibitor became more resistant to Plasmodium gallinaceum infection due to reduced anemia, thrombocytopenia and inflammation.
Topics: Anemia; Animals; Blood Chemical Analysis; Chickens; Enzyme Inhibitors; Fluorescent Antibody Techniqu | 2013 |
Nitric oxide does not contribute to inflammation-induced hypoferremia in humans.
Topics: Adolescent; Adult; Anemia, Iron-Deficiency; Antimicrobial Cationic Peptides; Cytokines; Endotoxemia; | 2007 |
44 other studies available for pimagedine and Inflammation
| Article | Year |
|---|---|
Lepidotol A from Mesua lepidota Inhibits Inflammatory and Immune Mediators in Human Endothelial Cells.
Topics: Anti-Inflammatory Agents; Cell Adhesion; Coumarins; Endothelial Cells; Fruit; Humans; Immunologic Fa | 2015 |
High-refined carbohydrate diet consumption induces neuroinflammation and anxiety-like behavior in mice.
Topics: Adipose Tissue; Animals; Anxiety; Behavior, Animal; Dietary Carbohydrates; Disease Models, Animal; G | 2020 |
The Cardioprotective Effects of Aminoguanidine on Lipopolysaccharide Induced Inflammation in Rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cardiotoxicity; Cardiovascular Diseases; Cardiovasc | 2020 |
Inducible nitric oxide synthase plays a role in depression- and anxiety-like behaviors chronically induced by lipopolysaccharide in rats: Evidence from inflammation and oxidative stress.
Topics: Animals; Anxiety; Anxiety Disorders; Cytokines; Depression; Depressive Disorder; Guanidines; Inflamm | 2020 |
Classically activated mouse macrophages produce methylglyoxal that induces a TLR4- and RAGE-independent proinflammatory response.
Topics: Aerobiosis; Animals; Cell Death; Cell Polarity; Cells, Cultured; Female; Glycolysis; Guanidines; Inf | 2021 |
Phloroglucinol prevents albumin glycation as well as diminishes ROS production, glycooxidative damage, nitrosative stress and inflammation in hepatocytes treated with high glucose.
Topics: Albumins; Antioxidants; Ascorbic Acid; Glucose; Glycation End Products, Advanced; Guanidines; Hep G2 | 2021 |
l-arginine modulates inflammation and muscle regulatory genes after a single session of resistance exercise in rats.
Topics: Adaptation, Physiological; Animals; Arginine; Guanidines; Inflammation; Interleukin-6; Male; Muscle | 2018 |
NF-κB-iNOS-COX2-TNF α inflammatory signaling pathway plays an important role in methotrexate induced small intestinal injury in rats.
Topics: Animals; Antimetabolites, Antineoplastic; Cyclooxygenase 2; Guanidines; Heme Oxygenase-1; HSP70 Heat | 2018 |
Anti-inflammatory effect of a sulphated polysaccharide fraction extracted from the red algae Hypnea musciformis via the suppression of neutrophil migration by the nitric oxide signalling pathway.
Topics: Animals; Anti-Inflammatory Agents; Arginine; Carrageenan; Dextrans; Edema; Enzyme Inhibitors; Guanid | 2013 |
Chronic inflammation-derived nitric oxide causes conversion of human colonic adenoma cells into adenocarcinoma cells.
Topics: Adenocarcinoma; Adenoma; Animals; Cell Line, Tumor; Cell Transformation, Neoplastic; Cells, Cultured | 2013 |
Effect of aminoguanidine intervention on neutrophils in diabetes inflammatory cells wound healing.
Topics: Animals; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Gene Expression Regulation; Guanidines; | 2013 |
Metformin attenuates the exacerbation of the allergic eosinophilic inflammation in high fat-diet-induced obesity in mice.
Topics: AMP-Activated Protein Kinases; Animals; Asthma; Blotting, Western; Bronchoalveolar Lavage Fluid; Die | 2013 |
Soft-tissue wound healing by anti-advanced glycation end-products agents.
Topics: Alveolar Process; Animals; Cell Adhesion Molecules; Cicatrix; Collagen; Collagen Type I; Down-Regula | 2014 |
Aminoguanidine treatment ameliorates inflammatory responses and memory impairment induced by amyloid-beta 25-35 injection in rats.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Guanidines; Inflammation; Male; Memory Disorders; | 2014 |
L-arginine and aminoguanidine reduce colonic damage of acetic acid-induced colitis in rats: potential modulation of nuclear factor-κB/p65.
Topics: Acetic Acid; Animals; Arginine; Body Weight; Colitis; Colon; Guanidines; Inflammation; Male; NF-kapp | 2014 |
iNOS inhibition improves autonomic dysfunction and oxidative status in hypertensive obese rats.
Topics: Animals; Arterial Pressure; Autonomic Nervous System; Dinoprostone; Enzyme Inhibitors; Guanidines; H | 2017 |
Inhibitory effects of aminoguanidine on thyroid follicular carcinoma development in inflamed capsular regions of rats treated with sulfadimethoxine after N-bis(2-hydroxypropyl)nitrosamine-initiation.
Topics: Adenocarcinoma, Follicular; Animals; Carcinogens; Cell Transformation, Neoplastic; Disease Progressi | 2009 |
Dual effect of nitric oxide on uterine prostaglandin synthesis in a murine model of preterm labour.
Topics: Animals; Blotting, Western; Cyclooxygenase 2 Inhibitors; Dinoprost; Dinoprostone; Disease Models, An | 2010 |
Potentiation of diclofenac-induced anti-inflammatory response by aminoguanidine in carrageenan-induced acute inflammation in rats: the role of nitric oxide.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Diclofenac; Drug Syner | 2003 |
Neutrophil migration in inflammation: nitric oxide inhibits rolling, adhesion and induces apoptosis.
Topics: Animals; Apoptosis; Carrageenan; Cell Adhesion; Chemotaxis, Leukocyte; Enzyme Inhibitors; Guanidines | 2003 |
Effects of aminoguanidine and cyclooxygenase inhibitors on nitric oxide and prostaglandin production, and nitric oxide synthase and cyclooxygenase expression induced by lipopolysaccharide in the estrogenized rat uterus.
Topics: Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprost; Dinopr | 2004 |
Lung microvascular permeability and neutrophil recruitment are differently regulated by nitric oxide in a rat model of intestinal ischemia-reperfusion.
Topics: Animals; Anti-Inflammatory Agents; Capillary Permeability; Dexamethasone; Guanidines; Inflammation; | 2004 |
Role of inducible nitric oxide synthase in N-methyl-d-aspartic acid-induced strio-nigral degeneration.
Topics: Animals; Functional Laterality; Guanidines; Immunohistochemistry; Inflammation; Interneurons; Male; | 2004 |
Activation of phosphoinositide 3-kinase in response to inflammation and nitric oxide leads to the up-regulation of cyclooxygenase-2 expression and subsequent cell proliferation in mesangial cells.
Topics: Animals; Cell Proliferation; Cells, Cultured; Chromones; Cyclooxygenase 2; Dose-Response Relationshi | 2005 |
Synergistic anti-inflammatory interaction between meloxicam and aminoguanidine hydrochloride in carrageenan-induced acute inflammation in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cyclooxygenase 2 Inhibitors; Dose-Res | 2006 |
Nitric oxide differentially regulates renal ATP-binding cassette transporters during endotoxemia.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, | 2007 |
Nitric oxide and the cyclooxygenase pathway.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Bradykinin; Dinoprostone; Enzyme Induction; Escherich | 1995 |
Toxic dilatation of colon in a rat model of colitis is linked to an inducible form of nitric oxide synthase.
Topics: Animals; Arginine; Colitis; Colon; Dexamethasone; Dilatation; Disease Models, Animal; Enzyme Inducti | 1996 |
Nitric oxide: a key mediator in the early and late phase of carrageenan-induced rat paw inflammation.
Topics: Animals; Carrageenan; Dinoprostone; Edema; Enzyme Inhibitors; Excipients; Free Radical Scavengers; G | 1996 |
The effect of inhibitors of inducible nitric oxide synthase on chronic colitis in the rhesus monkey.
Topics: Administration, Oral; Animals; Colitis, Ulcerative; Colon; Enzyme Inhibitors; Feces; Guanidines; Inf | 1997 |
Effect of the inducible nitric oxide synthase inhibitors aminoguanidine and L-N6-(1-iminoethyl)lysine on zymosan-induced plasma extravasation in rat skin.
Topics: Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanidines; Humans; Inflammation; Lysi | 1997 |
Injurious and protective mechanisms in the gut. Interaction of PAF, phospholipase A2, eicosanoids, and nitric oxide synthase.
Topics: Animals; Eicosanoids; Enzyme Activation; Enzyme Inhibitors; Group II Phospholipases A2; Guanidines; | 1997 |
Role of nitric oxide and peroxynitrite in the cytokine-induced sustained myocardial dysfunction in dogs in vivo.
Topics: Animals; Creatine Kinase; Cytokines; Dexamethasone; Disease Models, Animal; Dogs; Guanidines; Heart; | 1998 |
Expression, activity and cellular localization of inducible nitric oxide synthase in rat ileum and colon post-irradiation.
Topics: Animals; Arginine; Cesium Radioisotopes; Gamma Rays; Gene Expression Regulation, Enzymologic; Guanid | 1998 |
Neutrophil sequestration in the lung following acute aortic occlusion starts during ischaemia and can be attenuated by tumour necrosis factor and nitric oxide blockade.
Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents; Aorta; Chemotaxis; Constriction; Dexamethas | 1998 |
Tumour necrosis factor alpha induces only minor inflammatory changes in the central nervous system, but augments experimental meningitis.
Topics: Animals; Body Water; Brain; Cell Wall; Cerebrovascular Circulation; Dose-Response Relationship, Drug | 1998 |
Mycoplasma fermentans-induced inflammatory response of astrocytes: selective modulation by aminoguanidine, thalidomide, pentoxifylline and IL-10.
Topics: Animals; Astrocytes; Cells, Cultured; Enzyme Inhibitors; Guanidines; Inflammation; Interleukin-10; M | 1999 |
Antifungal type 1 responses are upregulated in IL-10-deficient mice.
Topics: Animals; Aspergillus fumigatus; Candida albicans; CD4 Antigens; Enzyme-Linked Immunosorbent Assay; F | 1999 |
Modulation of nitric oxide synthesis in inflammation. Relationship to oxygen-derived free radicals and prostaglandin synthesis.
Topics: Acetylglucosaminidase; Animals; Arthritis, Experimental; Carrageenan; Dinoprostone; Enzyme Inhibitor | 2000 |
Alterations in spontaneous contractions in vitro after repeated inflammation of rat distal colon.
Topics: Animals; Colitis; Colon; Disease Models, Animal; Gastrointestinal Motility; Guanidines; In Vitro Tec | 2001 |
7-Nitroindazole, but not aminoguanidine, attenuates the acute inflammatory responses and brain injury during the early phase of Escherichia coli meningitis in the newborn piglet.
Topics: Animals; Animals, Newborn; Blood Glucose; Brain Diseases; Cerebral Cortex; Cerebrospinal Fluid; Dise | 2001 |
Effects of nitric oxide synthase inhibitors on vascular hyperpermeability with thermal injury in mice.
Topics: Animals; Burns; Capillary Permeability; Dose-Response Relationship, Drug; Ear; Enzyme Inhibitors; Ev | 2001 |
Peripheral nitric oxide in carrageenan-induced inflammation.
Topics: Animals; Carrageenan; Drug Interactions; Edema; Enzyme Inhibitors; Guanidines; Hyperalgesia; Inflamm | 2001 |
Effects of aminoguanidine and meloxicam on nitric oxide and prostaglandin E production induced by lipopolysaccharide in the hypothalamus and anterior pituitary of the rat.
Topics: Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; End | 2001 |