pimagedine has been researched along with Hypertrophy in 7 studies
pimagedine: diamine oxidase & nitric oxide synthase inhibitor; an advanced glycosylation end product inhibitor; used in the treatment of diabetic complications; structure
aminoguanidine : A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.
Hypertrophy: General increase in bulk of a part or organ due to CELL ENLARGEMENT and accumulation of FLUIDS AND SECRETIONS, not due to tumor formation, nor to an increase in the number of cells (HYPERPLASIA).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Administration of the nitric oxide synthase (NOS) inhibitor, NG-nitro-L-arginine methyl ester (L-NAME) during pregnancy has been shown to compromise fetal growth." | 3.69 | Perinatal nitric oxide synthase inhibition retards neonatal growth by inducing hypertrophic pyloric stenosis in rats. ( Clark, DA; Eloby-Childress, S; Miller, MJ; Pierce, MR; Voelker, CA; Zhang, XJ, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (71.43) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cheng, YS | 1 |
| Dai, DZ | 1 |
| Dai, Y | 1 |
| Yang, CW | 2 |
| Vlassara, H | 1 |
| Striker, GE | 1 |
| Striker, LJ | 1 |
| Voelker, CA | 1 |
| Miller, MJ | 1 |
| Zhang, XJ | 1 |
| Eloby-Childress, S | 1 |
| Clark, DA | 1 |
| Pierce, MR | 1 |
| Oturai, PS | 1 |
| Rasch, R | 1 |
| Hasselager, E | 1 |
| Johansen, PB | 1 |
| Yokoyama, H | 1 |
| Thomsen, MK | 1 |
| Myrup, B | 1 |
| Kofoed-Enevoldsen, A | 1 |
| Deckert, T | 1 |
| Rumble, JR | 1 |
| Cooper, ME | 2 |
| Soulis, T | 1 |
| Cox, A | 1 |
| Wu, L | 1 |
| Youssef, S | 1 |
| Jasik, M | 1 |
| Jerums, G | 1 |
| Gilbert, RE | 2 |
| Yu, CC | 1 |
| Ko, YC | 1 |
| Huang, CC | 1 |
| Jandeleit-Dahm, K | 1 |
| Rumble, J | 1 |
| Cox, AJ | 1 |
| Kelly, DJ | 1 |
| Dziadek, M | 1 |
7 other studies available for pimagedine and Hypertrophy
| Article | Year |
|---|---|
Isoproterenol disperses distribution of NADPH oxidase, MMP-9, and pPKCepsilon in the heart, which are mitigated by endothelin receptor antagonist CPU0213.
Topics: Animals; Cardiotonic Agents; Endothelin Receptor Antagonists; Gene Expression Regulation; Guanidines | 2009 |
Administration of AGEs in vivo induces genes implicated in diabetic glomerulosclerosis.
Topics: Animals; Cell Count; Collagen; Diabetic Nephropathies; Female; Fluorescent Antibody Technique; Gene | 1995 |
Perinatal nitric oxide synthase inhibition retards neonatal growth by inducing hypertrophic pyloric stenosis in rats.
Topics: Animals; Animals, Newborn; Arginine; Body Weight; Disease Models, Animal; Embryonic and Fetal Develo | 1995 |
Effects of heparin and aminoguanidine on glomerular basement membrane thickening in diabetic rats.
Topics: Administration, Oral; Animals; Basement Membrane; Diabetes Mellitus, Experimental; Diabetic Nephropa | 1996 |
Vascular hypertrophy in experimental diabetes. Role of advanced glycation end products.
Topics: Animals; Blotting, Northern; Body Weight; Collagen; Diabetes Mellitus, Experimental; DNA Probes; Ext | 1997 |
Aminoguanidine reduces glomerular inducible nitric oxide synthase (iNOS) and transforming growth factor-beta 1 (TGF-beta1) mRNA expression and diminishes glomerulosclerosis in NZB/W F1 mice.
Topics: Animals; Body Weight; Cell Count; Creatine; Crosses, Genetic; Enzyme Inhibitors; Female; Guanidines; | 1998 |
SPARC gene expression is increased in diabetes-related mesenteric vascular hypertrophy.
Topics: Animals; Antibody Specificity; Blotting, Northern; Diabetes Mellitus, Experimental; Diabetic Angiopa | 2000 |