pimagedine has been researched along with Hypertension, Portal in 7 studies
pimagedine: diamine oxidase & nitric oxide synthase inhibitor; an advanced glycosylation end product inhibitor; used in the treatment of diabetic complications; structure
aminoguanidine : A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.
Hypertension, Portal: Abnormal increase of resistance to blood flow within the hepatic PORTAL SYSTEM, frequently seen in LIVER CIRRHOSIS and conditions with obstruction of the PORTAL VEIN.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This study investigated whether addition of aminoguanidine, a preferential inducible nitric oxide synthase inhibitor, to glypressin (a long-acting vasopressin analogue) could enhance its portal hypotensive effect in portal-hypertensive rats with bleeding." | 3.70 | Aminoguanidine ameliorates splanchnic hyposensitivity to glypressin in a haemorrhage-transfused rat model of portal hypertension. ( Chan, CC; Chang, FY; Chu, CJ; Hou, MC; Lee, FY; Lee, SD; Lin, HC; Tai, CC; Wang, SS; Wu, SL, 1998) |
| "Portal hypertension is often accompanied by a hyperdynamic circulation state." | 1.31 | Role of nitric oxide and endothelin-1 in a portal hypertensive rat model. ( Hashizume, M; Kawanaka, H; Kishihara, F; Migou, S; Sugimachi, K; Tanoue, K; Tomikawa, M; Tsugawa, K, 2000) |
| " This study investigated the effect of chronic administration of aminoguanidine, a selective inducible nitric oxide synthase inhibitor, to portal hypertensive rats on hemodynamics and the development of portal hypertensive gastropathy." | 1.30 | Aminoguanidine corrects hyperdynamic circulation without ameliorating portal hypertension and portal hypertensive gastropathy in anesthetized portal hypertensive rats. ( Chu, CJ; Lee, FY; Lee, SD; Lin, HC; Lin, HJ; Tai, CC; Tsai, YT; Wang, SS; Wu, SL, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (71.43) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, HC | 1 |
| Chang, CC | 1 |
| Wang, SS | 3 |
| Lee, FY | 3 |
| Teng, TH | 1 |
| Lee, JY | 1 |
| Lin, HC | 3 |
| Chuang, CL | 1 |
| Lee, SD | 3 |
| Heinemann, A | 1 |
| Stauber, RE | 1 |
| Tsai, YT | 1 |
| Lin, HJ | 1 |
| Chu, CJ | 2 |
| Wu, SL | 2 |
| Tai, CC | 2 |
| Michielsen, PP | 1 |
| Boeckxstaens, GE | 1 |
| Sys, SU | 1 |
| Herman, AG | 1 |
| Pelckmans, PA | 1 |
| Chang, FY | 1 |
| Hou, MC | 1 |
| Chan, CC | 1 |
| Gadano, AC | 1 |
| Sogni, P | 1 |
| Heller, J | 1 |
| Moreau, R | 1 |
| Bories, PN | 1 |
| Lebrec, D | 1 |
| Tsugawa, K | 1 |
| Hashizume, M | 1 |
| Migou, S | 1 |
| Kishihara, F | 1 |
| Kawanaka, H | 1 |
| Tomikawa, M | 1 |
| Tanoue, K | 1 |
| Sugimachi, K | 1 |
7 other studies available for pimagedine and Hypertension, Portal
| Article | Year |
|---|---|
The roles of angiotensin II receptors in the portosystemic collaterals of portal hypertensive and cirrhotic rats.
Topics: Animals; Collateral Circulation; Down-Regulation; Guanidines; Hypertension, Portal; Imidazoles; Liga | 2012 |
The role of inducible nitric oxide synthase in vascular hyporeactivity of endotoxin-treated and portal hypertensive rats.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Disease Models, Animal; Endotoxins; Enzyme Induction; | 1995 |
Aminoguanidine corrects hyperdynamic circulation without ameliorating portal hypertension and portal hypertensive gastropathy in anesthetized portal hypertensive rats.
Topics: Animals; Body Weight; Disease Models, Animal; Enzyme Inhibitors; Gastric Mucosa; Guanidines; Hemodyn | 1997 |
Aminoguanidine reverses aortic hyporeactivity to noradrenaline in portal vein-ligated rats.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Endothelium, Vascular; En | 1997 |
Aminoguanidine ameliorates splanchnic hyposensitivity to glypressin in a haemorrhage-transfused rat model of portal hypertension.
Topics: Animals; Drug Therapy, Combination; Guanidines; Hemodynamics; Hemorrhage; Hypertension, Portal; Lypr | 1998 |
Vascular nitric oxide production during the development of two experimental models of portal hypertension.
Topics: Animals; Aorta, Thoracic; Disease Models, Animal; Guanidines; Hypertension, Portal; In Vitro Techniq | 1999 |
Role of nitric oxide and endothelin-1 in a portal hypertensive rat model.
Topics: Animals; Blood Pressure; Disease Models, Animal; Endothelin-1; Enzyme Inhibitors; Guanidines; Hypert | 2000 |