pimagedine has been researched along with Hepatic Encephalopathy in 2 studies
pimagedine: diamine oxidase & nitric oxide synthase inhibitor; an advanced glycosylation end product inhibitor; used in the treatment of diabetic complications; structure
aminoguanidine : A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.
Hepatic Encephalopathy: A syndrome characterized by central nervous system dysfunction in association with LIVER FAILURE, including portal-systemic shunts. Clinical features include lethargy and CONFUSION (frequently progressing to COMA); ASTERIXIS; NYSTAGMUS, PATHOLOGIC; brisk oculovestibular reflexes; decorticate and decerebrate posturing; MUSCLE SPASTICITY; and bilateral extensor plantar reflexes (see REFLEX, BABINSKI). ELECTROENCEPHALOGRAPHY may demonstrate triphasic waves. (From Adams et al., Principles of Neurology, 6th ed, pp1117-20; Plum & Posner, Diagnosis of Stupor and Coma, 3rd ed, p222-5)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Its role in acute hepatic failure (AHF) is controversial." | 5.32 | The effects of early and late administration of inhibitors of inducible nitric oxide synthase in a thioacetamide-induced model of acute hepatic failure in the rat. ( Hodgson, HJ; Rahman, TM, 2003) |
| "Its role in acute hepatic failure (AHF) is controversial." | 1.32 | The effects of early and late administration of inhibitors of inducible nitric oxide synthase in a thioacetamide-induced model of acute hepatic failure in the rat. ( Hodgson, HJ; Rahman, TM, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Afifi, NA | 1 |
| Ramadan, A | 1 |
| Erian, EY | 1 |
| Sedik, AA | 1 |
| Amin, MM | 1 |
| Hassan, A | 1 |
| Saleh, DO | 1 |
| Rahman, TM | 1 |
| Hodgson, HJ | 1 |
2 other studies available for pimagedine and Hepatic Encephalopathy
| Article | Year |
|---|---|
Synergistic effect of aminoguanidine and l-carnosine against thioacetamide-induced hepatic encephalopathy in rats: behavioral, biochemical, and ultrastructural evidence.
Topics: Ammonia; Animals; Behavior, Animal; Brain; Brain Chemistry; Carnosine; Drug Synergism; Guanidines; H | 2021 |
The effects of early and late administration of inhibitors of inducible nitric oxide synthase in a thioacetamide-induced model of acute hepatic failure in the rat.
Topics: Ammonia; Animals; Enzyme Inhibitors; Guanidines; Hepatic Encephalopathy; Liver; Liver Failure, Acute | 2003 |