pimagedine has been researched along with Glomerulosclerosis, Focal Segmental in 3 studies
pimagedine: diamine oxidase & nitric oxide synthase inhibitor; an advanced glycosylation end product inhibitor; used in the treatment of diabetic complications; structure
aminoguanidine : A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.
Glomerulosclerosis, Focal Segmental: A clinicopathological syndrome or diagnostic term for a type of glomerular injury that has multiple causes, primary or secondary. Clinical features include PROTEINURIA, reduced GLOMERULAR FILTRATION RATE, and EDEMA. Kidney biopsy initially indicates focal segmental glomerular consolidation (hyalinosis) or scarring which can progress to globally sclerotic glomeruli leading to eventual KIDNEY FAILURE.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fujihara, CK | 1 |
| Mattar, AL | 1 |
| Vieira, JM | 1 |
| Malheiros, DM | 1 |
| Noronha, Ide L | 1 |
| Gonçalves, AR | 1 |
| De Nucci, G | 1 |
| Zatz, R | 1 |
| Reckelhoff, JF | 1 |
| Hennington, BS | 1 |
| Kanji, V | 1 |
| Racusen, LC | 1 |
| Schmidt, AM | 1 |
| Yan, SD | 1 |
| Morrow, J | 1 |
| Roberts, LJ | 1 |
| Salahudeen, AK | 1 |
| Kelly, DJ | 1 |
| Gilbert, RE | 1 |
| Cox, AJ | 1 |
| Soulis, T | 1 |
| Jerums, G | 1 |
| Cooper, ME | 1 |
3 other studies available for pimagedine and Glomerulosclerosis, Focal Segmental
| Article | Year |
|---|---|
Evidence for the existence of two distinct functions for the inducible NO synthase in the rat kidney: effect of aminoguanidine in rats with 5/6 ablation.
Topics: Animals; Blotting, Western; Enzyme Inhibitors; Glomerulosclerosis, Focal Segmental; Guanidines; Immu | 2002 |
Chronic aminoguanidine attenuates renal dysfunction and injury in aging rats.
Topics: Aging; Animals; Biomarkers; Blotting, Western; Dinoprost; Disease Models, Animal; Enzyme Inhibitors; | 1999 |
Aminoguanidine ameliorates overexpression of prosclerotic growth factors and collagen deposition in experimental diabetic nephropathy.
Topics: Animals; Autoradiography; Collagen; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Gene Ex | 2001 |