pimagedine has been researched along with Fibrosis in 8 studies
pimagedine: diamine oxidase & nitric oxide synthase inhibitor; an advanced glycosylation end product inhibitor; used in the treatment of diabetic complications; structure
aminoguanidine : A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.
Fibrosis: Any pathological condition where fibrous connective tissue invades any organ, usually as a consequence of inflammation or other injury.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A mouse model for diabetic nephropathy that encompasses the salient features of this disease in the kidney is not available." | 1.34 | Renal fibrosis and glomerulosclerosis in a new mouse model of diabetic nephropathy and its regression by bone morphogenic protein-7 and advanced glycation end product inhibitors. ( Grahovac, G; Kalluri, R; Sugimoto, H; Zeisberg, M, 2007) |
| "Bladder wall fibrosis is a sequela of recurrent urinary tract infection (UTI)." | 1.32 | Lipopolysaccharide and inflammatory cytokines cause an inducible nitric oxide synthase-dependent bladder smooth muscle fibrotic response. ( Austin, PF; Cain, MP; Casale, AJ; Rink, RC; Weintraub, SJ, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 4 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Parthasarathy, A | 1 |
| Gopi, V | 1 |
| Devi K M, S | 1 |
| Balaji, N | 1 |
| Vellaichamy, E | 2 |
| Vadla, GP | 1 |
| Maulik, SK | 1 |
| Prabhakar, P | 1 |
| Dinda, AK | 1 |
| Seth, S | 1 |
| Malaviya, R | 1 |
| Venosa, A | 1 |
| Hall, L | 1 |
| Gow, AJ | 1 |
| Sinko, PJ | 1 |
| Laskin, JD | 1 |
| Laskin, DL | 1 |
| Austin, PF | 1 |
| Casale, AJ | 1 |
| Cain, MP | 1 |
| Rink, RC | 1 |
| Weintraub, SJ | 1 |
| Zareie, M | 1 |
| Tangelder, GJ | 1 |
| ter Wee, PM | 1 |
| Hekking, LH | 1 |
| van Lambalgen, AA | 1 |
| Keuning, ED | 1 |
| Schadee-Eestermans, IL | 1 |
| Schalkwijk, CG | 1 |
| Beelen, RH | 1 |
| van den Born, J | 1 |
| Sugimoto, H | 1 |
| Grahovac, G | 1 |
| Zeisberg, M | 1 |
| Kalluri, R | 1 |
| Tang, SS | 1 |
| Chichester, CO | 1 |
| Kagan, HM | 1 |
8 other studies available for pimagedine and Fibrosis
| Article | Year |
|---|---|
Aminoguanidine inhibits ventricular fibrosis and remodeling process in isoproterenol-induced hypertrophied rat hearts by suppressing ROS and MMPs.
Topics: Animals; Antioxidants; Cardiomegaly; Fibrosis; Guanidines; Heart Ventricles; Isoproterenol; Male; Ma | 2014 |
Anti-fibrotic cardio protective efficacy of aminoguanidine against streptozotocin induced cardiac fibrosis and high glucose induced collagen up regulation in cardiac fibroblasts.
Topics: Animals; Cardiotonic Agents; Collagen; Diabetes Mellitus, Experimental; Fibrosis; Gene Expression Re | 2012 |
Genistein prevents isoproterenol-induced cardiac hypertrophy in rats.
Topics: Animals; Cardiomegaly; Cardiotonic Agents; Catalase; Disease Models, Animal; Enzyme Inhibitors; Fibr | 2012 |
Attenuation of acute nitrogen mustard-induced lung injury, inflammation and fibrogenesis by a nitric oxide synthase inhibitor.
Topics: Animals; Bronchoalveolar Lavage Fluid; Drug Interactions; Enzyme Inhibitors; Fibrosis; Guanidines; H | 2012 |
Lipopolysaccharide and inflammatory cytokines cause an inducible nitric oxide synthase-dependent bladder smooth muscle fibrotic response.
Topics: Cells, Cultured; Collagen Type III; Cytokines; Fibrosis; Guanidines; Humans; Inflammation Mediators; | 2003 |
Beneficial effects of aminoguanidine on peritoneal microcirculation and tissue remodelling in a rat model of PD.
Topics: Animals; Dialysis Solutions; Disease Models, Animal; Enzyme Inhibitors; Fibrosis; Glycation End Prod | 2005 |
Renal fibrosis and glomerulosclerosis in a new mouse model of diabetic nephropathy and its regression by bone morphogenic protein-7 and advanced glycation end product inhibitors.
Topics: Animals; Bone Morphogenetic Protein 7; Bone Morphogenetic Proteins; Diabetic Nephropathies; Disease | 2007 |
Comparative sensitivities of purified preparations of lysyl oxidase and other amine oxidases to active site-directed enzyme inhibitors.
Topics: Amine Oxidase (Copper-Containing); Amino Acid Oxidoreductases; Aminopropionitrile; Animals; Binding | 1989 |