pimagedine has been researched along with Epilepsy, Tonic-Clonic in 2 studies
pimagedine: diamine oxidase & nitric oxide synthase inhibitor; an advanced glycosylation end product inhibitor; used in the treatment of diabetic complications; structure
aminoguanidine : A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.
Epilepsy, Tonic-Clonic: A generalized seizure disorder characterized by recurrent major motor seizures. The initial brief tonic phase is marked by trunk flexion followed by diffuse extension of the trunk and extremities. The clonic phase features rhythmic flexor contractions of the trunk and limbs, pupillary dilation, elevations of blood pressure and pulse, urinary incontinence, and tongue biting. This is followed by a profound state of depressed consciousness (post-ictal state) which gradually improves over minutes to hours. The disorder may be cryptogenic, familial, or symptomatic (caused by an identified disease process). (From Adams et al., Principles of Neurology, 6th ed, p329)
| Excerpt | Relevance | Reference |
|---|---|---|
| " This study was designed to investigate whether acute or subchronic treatment with coenzyme Q10 altered the seizures induced by pentylenetetrazole or electroshock in mice." | 7.80 | The effects of coenzyme Q10 on seizures in mice: the involvement of nitric oxide. ( Moezi, L; Mousavi, Z; Sattarinezhad, E; Shafaroodi, H; Sheikhnouri, K, 2014) |
| " This study was designed to investigate whether acute or subchronic treatment with coenzyme Q10 altered the seizures induced by pentylenetetrazole or electroshock in mice." | 3.80 | The effects of coenzyme Q10 on seizures in mice: the involvement of nitric oxide. ( Moezi, L; Mousavi, Z; Sattarinezhad, E; Shafaroodi, H; Sheikhnouri, K, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sattarinezhad, E | 1 |
| Shafaroodi, H | 2 |
| Sheikhnouri, K | 1 |
| Mousavi, Z | 1 |
| Moezi, L | 2 |
| Fakhrzad, A | 1 |
| Hassanipour, M | 1 |
| Rezayat, M | 1 |
| Dehpour, AR | 1 |
2 other studies available for pimagedine and Epilepsy, Tonic-Clonic
| Article | Year |
|---|---|
The effects of coenzyme Q10 on seizures in mice: the involvement of nitric oxide.
Topics: Animals; Arginine; Brain; Disease Models, Animal; Electroshock; Epilepsy, Tonic-Clonic; Guanidines; | 2014 |
The involvement of nitric oxide in the anti-seizure effect of acute atorvastatin treatment in mice.
Topics: Animals; Anticonvulsants; Atorvastatin; Brain; Convulsants; Disease Models, Animal; Dose-Response Re | 2012 |