pimagedine has been researched along with Endolymphatic Hydrops in 2 studies
pimagedine: diamine oxidase & nitric oxide synthase inhibitor; an advanced glycosylation end product inhibitor; used in the treatment of diabetic complications; structure
aminoguanidine : A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.
Endolymphatic Hydrops: An accumulation of ENDOLYMPH in the inner ear (LABYRINTH) leading to buildup of pressure and distortion of intralabyrinthine structures, such as COCHLEA and SEMICIRCULAR CANALS. It is characterized by SENSORINEURAL HEARING LOSS; TINNITUS; and sometimes VERTIGO.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Aminoguanidine treated animals (n = 5) also sustained nerve deterioration to the same degree as non-treated animals and there appeared to be no protective effect (at the dosage administered) against ELH related hearing loss, hydrops formation, or nerve deterioration." | 1.33 | Diameter of the cochlear nerve in endolymphatic hydrops: implications for the etiology of hearing loss in Ménière's disease. ( Megerian, CA, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Megerian, CA | 1 |
| Ikino, CM | 1 |
| Bittar, RS | 1 |
| Sato, KM | 1 |
| Capella, NM | 1 |
2 other studies available for pimagedine and Endolymphatic Hydrops
| Article | Year |
|---|---|
Diameter of the cochlear nerve in endolymphatic hydrops: implications for the etiology of hearing loss in Ménière's disease.
Topics: Animals; Cochlear Nerve; Endolymphatic Hydrops; Enzyme Inhibitors; Female; Guanidines; Guinea Pigs; | 2005 |
Effects of a nitric oxide synthase Type II inhibitor on compound action potential thresholds in experimental endolymphatic hydrops.
Topics: Action Potentials; Animals; Audiometry, Evoked Response; Cochlea; Endolymphatic Hydrops; Female; Gua | 2007 |