pimagedine and Edema
pimagedine has been researched along with Edema in 13 studies
pimagedine: diamine oxidase & nitric oxide synthase inhibitor; an advanced glycosylation end product inhibitor; used in the treatment of diabetic complications; structure
aminoguanidine : A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.
Edema: Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| " Diclofenac significantly reduced the carrageenan-induced edema in rat paw at all the time points studied." | 7.72 | Potentiation of diclofenac-induced anti-inflammatory response by aminoguanidine in carrageenan-induced acute inflammation in rats: the role of nitric oxide. ( Al-Majed, AA; Al-Shabanah, OA; Khattab, M; Mostafa, AM; Raza, M, 2003) |
| " Diclofenac significantly reduced the carrageenan-induced edema in rat paw at all the time points studied." | 3.72 | Potentiation of diclofenac-induced anti-inflammatory response by aminoguanidine in carrageenan-induced acute inflammation in rats: the role of nitric oxide. ( Al-Majed, AA; Al-Shabanah, OA; Khattab, M; Mostafa, AM; Raza, M, 2003) |
| " The optimal dosage of AG was screened by dry-wet weight method with the percentage of water content at 0, 12, 24, and 48 hours after injury." | 1.38 | [Effect of aminoguanidine on spinal cord edema of acute spinal cord injury in rats]. ( Cao, Y; Fan, Z; Lü, G; Mei, X; Wang, Y; Yu, D; Zhang, M; Zhang, Z, 2012) |
| " Compared to SCI group without treatment, AG at the dosage of 150mg/kg induced a reduction in the permeability of blood-spinal cord barrier (BSCB) after injury 48h (from 59." | 1.36 | The effect of aminoguanidine on compression spinal cord injury in rats. ( Cao, Y; Fan, ZK; Lu, W; Lv, G; Wang, YF; Zhang, MC; Zhang, YQ; Zhang, Z, 2010) |
| "Myocardial edema has previously been implicated in diastolic dysfunction during allograft rejection." | 1.31 | Improvement of rejection-induced diastolic abnormalities in rat cardiac allografts with inducible nitric oxide synthase inhibition. ( Carter, YM; Fisher, PE; Hart, JP; Hsu, DT; Jia, CX; Pinsky, DJ; Rabkin, DG; Sardo, MJ; Soto, PF; Spotnitz, HM, 2000) |
| "The role of nitric oxide in allergic conjunctivitis was studied in a guinea pig model." | 1.29 | Nitric oxide plays a role as a mediator of conjunctival edema in experimental allergic conjunctivitis. ( Garrelds, IM; Kijlstra, A; Meijer, F; Van Delft, JL; Van Haeringen, NJ, 1996) |
| "3 Paw oedema was maximal by 6 h and remained elevated for 10 h following carrageenan administration." | 1.29 | Nitric oxide: a key mediator in the early and late phase of carrageenan-induced rat paw inflammation. ( Bourdon, DM; Currie, MG; Manning, PT; Marino, MH; Salvemini, D; Wang, ZQ; Wyatt, PS, 1996) |
| "Paw edema was inhibited 8 h following the administration of carrageenan by N-iminoethyl-L-lysine (3-30 mg/kg, n = 6) or aminoguanidine (30-300 mg/kg, n = 6), two selective inhibitors of inducible nitric oxide synthase and by recombinant human Cu/Zn superoxide dismutase coupled to polyethyleneglycol (12 x 10(3) U/kg, n = 6, P < 0." | 1.29 | Evidence of peroxynitrite involvement in the carrageenan-induced rat paw edema. ( Bourdon, DM; Currie, MG; Manning, PT; Salvemini, D; Stern, MK; Wang, ZQ, 1996) |
Research
Studies (13)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (30.77) | 18.2507 |
| 2000's | 6 (46.15) | 29.6817 |
| 2010's | 3 (23.08) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| de Brito, TV | 1 |
| Prudêncio, Rda S | 1 |
| Sales, AB | 1 |
| Vieira, Fd | 1 |
| Candeira, SJ | 1 |
| Franco, ÁX | 1 |
| Aragão, KS | 1 |
| Ribeiro, Rde A | 1 |
| Ponte de Souza, MH | 1 |
| Chaves, Lde S | 1 |
| Freitas, AL | 1 |
| Medeiros, JV | 1 |
| dos Reis Barbosa, AL | 1 |
| Fan, ZK | 1 |
| Wang, YF | 1 |
| Cao, Y | 2 |
| Zhang, MC | 1 |
| Zhang, Z | 2 |
| Lv, G | 1 |
| Lu, W | 1 |
| Zhang, YQ | 1 |
| Fan, Z | 1 |
| Wang, Y | 1 |
| Yu, D | 1 |
| Zhang, M | 1 |
| Mei, X | 1 |
| Lü, G | 1 |
| Al-Majed, AA | 1 |
| Khattab, M | 1 |
| Raza, M | 1 |
| Al-Shabanah, OA | 1 |
| Mostafa, AM | 1 |
| Chaves, F | 1 |
| Teixeira, CF | 1 |
| Gutiérrez, JM | 1 |
| Meijer, F | 1 |
| Van Delft, JL | 1 |
| Garrelds, IM | 1 |
| Van Haeringen, NJ | 1 |
| Kijlstra, A | 1 |
| Salvemini, D | 2 |
| Wang, ZQ | 2 |
| Wyatt, PS | 1 |
| Bourdon, DM | 2 |
| Marino, MH | 1 |
| Manning, PT | 2 |
| Currie, MG | 2 |
| Stern, MK | 1 |
| Nishino, T | 1 |
| Watanabe, S | 1 |
| Oyama, H | 1 |
| Fukuya, Y | 1 |
| Hayashi, N | 1 |
| Kobayashi, M | 1 |
| Soto, PF | 1 |
| Jia, CX | 1 |
| Rabkin, DG | 1 |
| Hart, JP | 1 |
| Carter, YM | 1 |
| Sardo, MJ | 1 |
| Hsu, DT | 1 |
| Fisher, PE | 1 |
| Pinsky, DJ | 1 |
| Spotnitz, HM | 1 |
| Brisby, H | 1 |
| Byröd, G | 1 |
| Olmarker, K | 1 |
| Miller, VM | 1 |
| Aoki, Y | 1 |
| Rydevik, B | 1 |
| Omote, K | 1 |
| Hazama, K | 1 |
| Kawamata, T | 1 |
| Kawamata, M | 1 |
| Nakayaka, Y | 1 |
| Toriyabe, M | 1 |
| Namiki, A | 1 |
| da S Rocha, JC | 1 |
| Peixoto, ME | 1 |
| Jancar, S | 1 |
| de Q Cunha, F | 1 |
| de A Ribeiro, R | 1 |
| da Rocha, FA | 1 |
Other Studies
13 other studies available for pimagedine and Edema
| Article | Year |
|---|---|
Anti-inflammatory effect of a sulphated polysaccharide fraction extracted from the red algae Hypnea musciformis via the suppression of neutrophil migration by the nitric oxide signalling pathway.
Topics: Animals; Anti-Inflammatory Agents; Arginine; Carrageenan; Dextrans; Edema; Enzyme Inhibitors; Guanid | 2013 |
The effect of aminoguanidine on compression spinal cord injury in rats.
Topics: Animals; Antioxidants; Edema; Guanidines; Male; Neuroprotective Agents; Oxidative Stress; Rats; Rats | 2010 |
[Effect of aminoguanidine on spinal cord edema of acute spinal cord injury in rats].
Topics: Acute Disease; Animals; Aquaporin 4; Blood-Brain Barrier; Blotting, Western; Disease Models, Animal; | 2012 |
Potentiation of diclofenac-induced anti-inflammatory response by aminoguanidine in carrageenan-induced acute inflammation in rats: the role of nitric oxide.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Diclofenac; Drug Syner | 2003 |
Role of nitric oxide in the local and systemic pathophysiological effects induced by Bothrops asper snake venom in mice.
Topics: Animals; Bothrops; Crotalid Venoms; Edema; Enzyme Inhibitors; Guanidines; Hemorrhage; Mice; Muscle, | 2006 |
Nitric oxide plays a role as a mediator of conjunctival edema in experimental allergic conjunctivitis.
Topics: Animals; Arginine; Capillary Permeability; Conjunctival Diseases; Conjunctivitis, Allergic; Dose-Res | 1996 |
Nitric oxide: a key mediator in the early and late phase of carrageenan-induced rat paw inflammation.
Topics: Animals; Carrageenan; Dinoprostone; Edema; Enzyme Inhibitors; Excipients; Free Radical Scavengers; G | 1996 |
Evidence of peroxynitrite involvement in the carrageenan-induced rat paw edema.
Topics: Animals; Carrageenan; Edema; Guanidines; Male; Nitrates; Nitric Oxide Synthase; Rats; Rats, Sprague- | 1996 |
An endothelial nitric oxide synthase inhibitor aggravates CDL-induced acute pancreatitis in rats.
Topics: Acute Disease; Animals; Arginine; Ascitic Fluid; Duodenum; Edema; Enzyme Inhibitors; Guanidines; Lig | 1999 |
Improvement of rejection-induced diastolic abnormalities in rat cardiac allografts with inducible nitric oxide synthase inhibition.
Topics: Animals; Cardiomyopathies; Dexamethasone; Diastole; Edema; Graft Rejection; Guanidines; Heart Transp | 2000 |
Nitric oxide as a mediator of nucleus pulposus-induced effects on spinal nerve roots.
Topics: Animals; Capillary Permeability; Edema; Enzyme Inhibitors; Female; Guanidines; Intervertebral Disc; | 2000 |
Peripheral nitric oxide in carrageenan-induced inflammation.
Topics: Animals; Carrageenan; Drug Interactions; Edema; Enzyme Inhibitors; Guanidines; Hyperalgesia; Inflamm | 2001 |
Dual effect of nitric oxide in articular inflammatory pain in zymosan-induced arthritis in rats.
Topics: Amidines; Animals; Arthritis, Experimental; Benzylamines; Cartilage, Articular; Dinoprost; Edema; En | 2002 |