pimagedine has been researched along with Disease Exacerbation in 20 studies
pimagedine: diamine oxidase & nitric oxide synthase inhibitor; an advanced glycosylation end product inhibitor; used in the treatment of diabetic complications; structure
aminoguanidine : A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the effect of carnosine (CA), aminoguanidine (AG), and aspirin (ASA) drops, all inhibitors of glycation, on the development of diabetic cataract in rat." | 7.74 | Effect of carnosine, aminoguanidine, and aspirin drops on the prevention of cataracts in diabetic rats. ( Ding, Z; Guo, Y; Ha, W; Harding, JJ; Yan, H; Zhang, J, 2008) |
| "We have reported that thyroid capsular thickening with inflammation induced by an antithyroidal agent, sulfadimethoxine (SDM), might play a role in the development of invasive follicular carcinomas in rats initiated with N-bis(2-hydroxypropyl)nitrosamine (DHPN)." | 3.75 | Inhibitory effects of aminoguanidine on thyroid follicular carcinoma development in inflamed capsular regions of rats treated with sulfadimethoxine after N-bis(2-hydroxypropyl)nitrosamine-initiation. ( Cho, YM; Hasumura, M; Hirose, M; Imai, T; Nishikawa, A; Ota, Y; Takami, S, 2009) |
| "To investigate the effect of carnosine (CA), aminoguanidine (AG), and aspirin (ASA) drops, all inhibitors of glycation, on the development of diabetic cataract in rat." | 3.74 | Effect of carnosine, aminoguanidine, and aspirin drops on the prevention of cataracts in diabetic rats. ( Ding, Z; Guo, Y; Ha, W; Harding, JJ; Yan, H; Zhang, J, 2008) |
| "Diabetic nephropathy is the leading cause of end-stage renal disease, and both the incidence and prevalence of diabetic nephropathy continue to increase." | 2.46 | Potential new therapeutic agents for diabetic kidney disease. ( Bolton, WK; Turgut, F, 2010) |
| "Mycetoma is a chronic infectious disease that can be caused by fungi or bacteria, Madurella mycetomatis and Nocardia brasiliensis are frequent etiologic agents of this disease." | 1.56 | Inducible nitric oxide synthase blockade with aminoguanidine, protects mice infected with Nocardia brasiliensis from actinomycetoma development. ( Garza-Esquivel, HR; Longoria-Lozano, O; López-Ulloa, J; Reyes-Carrillo, J; Salinas-Carmona, MC; Vázquez-Marmolejo, AV, 2020) |
| "In the induction sites, periodontal bone loss was significantly reduced (P <0." | 1.40 | Aminoguanidine inhibits the AGE-RAGE axis to modulate the induction of periodontitis but has limited effects on the progression and recovery of experimental periodontitis: a preliminary study. ( Chang, PC; Chong, LY; Lim, LP; Tsai, SC, 2014) |
| "Both abdominal aortic aneurysms (AAAs) and inducible nitric oxide synthase (iNOS) are associated with inflammatory states, yet the relationship between NO production by iNOS and AAA development is unknown." | 1.31 | Inhibition of inducible nitric oxide synthase limits nitric oxide production and experimental aneurysm expansion. ( Carey, DJ; Elmore, JR; Franklin, DP; Han, DC; Johanning, JM, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (20.00) | 18.2507 |
| 2000's | 10 (50.00) | 29.6817 |
| 2010's | 5 (25.00) | 24.3611 |
| 2020's | 1 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| Salinas-Carmona, MC | 1 |
| Longoria-Lozano, O | 1 |
| Garza-Esquivel, HR | 1 |
| López-Ulloa, J | 1 |
| Reyes-Carrillo, J | 1 |
| Vázquez-Marmolejo, AV | 1 |
| Zhan, Z | 1 |
| Liu, R | 1 |
| Chai, L | 1 |
| Dai, Y | 1 |
| Lv, Y | 1 |
| Chang, PC | 1 |
| Chong, LY | 1 |
| Tsai, SC | 1 |
| Lim, LP | 1 |
| Heinecke, JL | 1 |
| Ridnour, LA | 1 |
| Cheng, RY | 1 |
| Switzer, CH | 1 |
| Lizardo, MM | 1 |
| Khanna, C | 1 |
| Glynn, SA | 1 |
| Hussain, SP | 1 |
| Young, HA | 1 |
| Ambs, S | 1 |
| Wink, DA | 1 |
| Wang, S | 1 |
| Li, B | 1 |
| Li, C | 1 |
| Cui, W | 1 |
| Miao, L | 1 |
| Yan, H | 1 |
| Guo, Y | 1 |
| Zhang, J | 1 |
| Ding, Z | 1 |
| Ha, W | 1 |
| Harding, JJ | 1 |
| Kuprjanowicz, L | 1 |
| Karczewicz, D | 1 |
| Imai, T | 1 |
| Hasumura, M | 1 |
| Cho, YM | 1 |
| Ota, Y | 1 |
| Takami, S | 1 |
| Hirose, M | 1 |
| Nishikawa, A | 1 |
| Turgut, F | 1 |
| Bolton, WK | 1 |
| Nagai, N | 1 |
| Fukuhata, T | 1 |
| Ito, Y | 1 |
| Zhang, HY | 1 |
| Han, DW | 1 |
| Su, AR | 1 |
| Zhang, LT | 1 |
| Zhao, ZF | 1 |
| Ji, JQ | 1 |
| Li, BH | 1 |
| Ji, C | 1 |
| Swamy-Mruthinti, S | 1 |
| Green, K | 1 |
| Abraham, EC | 1 |
| Ishiyama, S | 1 |
| Hiroe, M | 1 |
| Nishikawa, T | 1 |
| Abe, S | 1 |
| Shimojo, T | 1 |
| Ito, H | 1 |
| Ozasa, S | 1 |
| Yamakawa, K | 1 |
| Matsuzaki, M | 1 |
| Mohammed, MU | 1 |
| Nakazawa, H | 1 |
| Kasajima, T | 1 |
| Marumo, F | 1 |
| Okuda, Y | 1 |
| Sakoda, S | 1 |
| Fujimura, H | 1 |
| Yanagihara, T | 1 |
| Hwang, TL | 1 |
| Yang, JT | 1 |
| Lau, YT | 1 |
| Pozza, M | 1 |
| Bettelli, C | 1 |
| Aloe, L | 1 |
| Giardino, L | 1 |
| Calzà, L | 1 |
| Johanning, JM | 1 |
| Franklin, DP | 1 |
| Han, DC | 1 |
| Carey, DJ | 1 |
| Elmore, JR | 1 |
| Benencia, F | 1 |
| Courrèges, MC | 1 |
| Gamba, G | 1 |
| Cavalieri, H | 1 |
| Massouh, EJ | 1 |
| Ishibashi, Y | 1 |
| Shimada, T | 1 |
| Murakami, Y | 1 |
| Takahashi, N | 1 |
| Sakane, T | 1 |
| Sugamori, T | 1 |
| Ohata, S | 1 |
| Inoue, S | 1 |
| Ohta, Y | 1 |
| Nakamura, K | 1 |
| Shimizu, H | 1 |
| Katoh, H | 1 |
| Hashimoto, M | 1 |
| Degenhardt, TP | 1 |
| Alderson, NL | 1 |
| Arrington, DD | 1 |
| Beattie, RJ | 1 |
| Basgen, JM | 1 |
| Steffes, MW | 1 |
| Thorpe, SR | 1 |
| Baynes, JW | 1 |
3 reviews available for pimagedine and Disease Exacerbation
| Article | Year |
|---|---|
Potential Renoprotective Agents through Inhibiting CTGF/CCN2 in Diabetic Nephropathy.
Topics: Animals; Anthocyanins; Antibodies, Monoclonal; Connective Tissue Growth Factor; Diabetes Mellitus; D | 2015 |
[Neuroprotection in glaucoma].
Topics: Betaxolol; Brimonidine Tartrate; Disease Progression; Glaucoma; Guanidines; Humans; Memantine; Neuro | 2007 |
Potential new therapeutic agents for diabetic kidney disease.
Topics: Amides; Animals; Clinical Trials as Topic; Connective Tissue Growth Factor; Diabetic Nephropathies; | 2010 |
17 other studies available for pimagedine and Disease Exacerbation
| Article | Year |
|---|---|
Inducible nitric oxide synthase blockade with aminoguanidine, protects mice infected with Nocardia brasiliensis from actinomycetoma development.
Topics: Animals; Disease Progression; Female; Guanidines; Humans; Macrophages; Mice; Mice, Inbred BALB C; My | 2020 |
Visualization of Lung Inflammation to Pulmonary Fibrosis via Peroxynitrite Fluctuation.
Topics: Disease Progression; Fluorescent Dyes; Guanidines; Humans; Idiopathic Pulmonary Fibrosis; Mitochondr | 2019 |
Aminoguanidine inhibits the AGE-RAGE axis to modulate the induction of periodontitis but has limited effects on the progression and recovery of experimental periodontitis: a preliminary study.
Topics: Alveolar Bone Loss; Alveolar Process; Angiogenesis Inducing Agents; Animals; Biomarkers; Cell Adhesi | 2014 |
Tumor microenvironment-based feed-forward regulation of NOS2 in breast cancer progression.
Topics: Animals; Biomarkers, Tumor; Breast Neoplasms; Cell Hypoxia; Cell Line, Tumor; Cell Movement; Cell Pr | 2014 |
Effect of carnosine, aminoguanidine, and aspirin drops on the prevention of cataracts in diabetic rats.
Topics: Animals; Aspirin; Blood Glucose; Body Weight; Carnosine; Cataract; Cornea; Diabetes Mellitus, Experi | 2008 |
Inhibitory effects of aminoguanidine on thyroid follicular carcinoma development in inflamed capsular regions of rats treated with sulfadimethoxine after N-bis(2-hydroxypropyl)nitrosamine-initiation.
Topics: Adenocarcinoma, Follicular; Animals; Carcinogens; Cell Transformation, Neoplastic; Disease Progressi | 2009 |
Effect of magnesium deficiency on intracellular ATP levels in human lens epithelial cells.
Topics: Adenosine Triphosphate; Calcium-Transporting ATPases; Cataract; Cell Line; Chelating Agents; Disease | 2007 |
Intestinal endotoxemia plays a central role in development of hepatopulmonary syndrome in a cirrhotic rat model induced by multiple pathogenic factors.
Topics: Alanine Transaminase; Animals; Bronchoalveolar Lavage Fluid; Capillaries; Carboxyhemoglobin; Cytokin | 2007 |
Inhibition of cataracts in moderately diabetic rats by aminoguanidine.
Topics: Animals; Cataract; Diabetes Mellitus, Experimental; Disease Progression; Glycation End Products, Adv | 1996 |
Nitric oxide contributes to the progression of myocardial damage in experimental autoimmune myocarditis in rats.
Topics: Animals; Autoimmune Diseases; Disease Progression; Enzyme Inhibitors; Female; Guanidines; Immunohist | 1997 |
Aminoguanidine, a selective inhibitor of the inducible nitric oxide synthase, has different effects on experimental allergic encephalomyelitis in the induction and progression phase.
Topics: Acute Disease; Animals; Autoimmune Diseases; Disease Progression; Drug Administration Schedule; Ence | 1998 |
Arginine-nitric oxide pathway in plasma membrane of rat hepatocytes during early and late sepsis.
Topics: Animals; Arginine; Bacteremia; Biological Transport; Cell Membrane; Critical Illness; Disease Progre | 1999 |
Further evidence for a role of nitric oxide in experimental allergic encephalomyelitis: aminoguanidine treatment modifies its clinical evolution.
Topics: Acute Disease; Animals; Brain; Demyelinating Diseases; Disease Progression; Encephalomyelitis, Autoi | 2000 |
Inhibition of inducible nitric oxide synthase limits nitric oxide production and experimental aneurysm expansion.
Topics: Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Disease Models, Animal; Disease Progression; | 2001 |
Effect of aminoguanidine, a nitric oxide synthase inhibitor, on ocular infection with herpes simplex virus in Balb/c mice.
Topics: Administration, Topical; Animals; Cornea; Disease Progression; DNA, Viral; Dose-Response Relationshi | 2001 |
An inhibitor of inducible nitric oxide synthase decreases forearm blood flow in patients with congestive heart failure.
Topics: Acetylcholine; Adult; Aged; Analysis of Variance; Atrial Natriuretic Factor; Blood Flow Velocity; Ca | 2001 |
Pyridoxamine inhibits early renal disease and dyslipidemia in the streptozotocin-diabetic rat.
Topics: Animals; Collagen; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Progression; Fem | 2002 |