pimagedine has been researched along with Colitis in 14 studies
pimagedine: diamine oxidase & nitric oxide synthase inhibitor; an advanced glycosylation end product inhibitor; used in the treatment of diabetic complications; structure
aminoguanidine : A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.
Colitis: Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This study evaluated the anti-inflammatory effects of licofelone on acetic acid-induced colitis in rats." | 8.31 | Licofelone Attenuates Acetic Acid-Induced Colitis in Rats Through Suppression of the Inflammatory Mediators. ( Abdolghaffari, AH; Abdollahi, AR; Baeeri, M; Dehpour, AR; Khayatan, D; Lashgari, NA; Momtaz, S; Roudsari, NM; Shahraki, FN, 2023) |
| " The aim of the present study was to investigate the potential protective effect of l-arginine (Arg; nitric oxide precursor) and aminoguanidine (inducible nitric oxide synthase inhibitor) against acetic acid (AA)-induced colitis in rats, and the potential role of NF-κB." | 7.80 | L-arginine and aminoguanidine reduce colonic damage of acetic acid-induced colitis in rats: potential modulation of nuclear factor-κB/p65. ( Farghaly, HS; Thabit, RH, 2014) |
| "TNF-α-colitis was characterized by hemorrhagic edemas and crypt abscesses massively infiltrated by inflammatory cells, namely neutrophils." | 5.38 | Aminoguanidine and curcumin attenuated tumor necrosis factor (TNF)-α-induced oxidative stress, colitis and hepatotoxicity in mice. ( Djerdjouri, B; Mouzaoui, S; Rahim, I, 2012) |
| " This study evaluated the anti-inflammatory effects of licofelone on acetic acid-induced colitis in rats." | 4.31 | Licofelone Attenuates Acetic Acid-Induced Colitis in Rats Through Suppression of the Inflammatory Mediators. ( Abdolghaffari, AH; Abdollahi, AR; Baeeri, M; Dehpour, AR; Khayatan, D; Lashgari, NA; Momtaz, S; Roudsari, NM; Shahraki, FN, 2023) |
| " The aim of the present study was to investigate the potential protective effect of l-arginine (Arg; nitric oxide precursor) and aminoguanidine (inducible nitric oxide synthase inhibitor) against acetic acid (AA)-induced colitis in rats, and the potential role of NF-κB." | 3.80 | L-arginine and aminoguanidine reduce colonic damage of acetic acid-induced colitis in rats: potential modulation of nuclear factor-κB/p65. ( Farghaly, HS; Thabit, RH, 2014) |
| "Colitis was induced by intrarectal (i." | 1.43 | Behavioral despair associated with a mouse model of Crohn's disease: Role of nitric oxide pathway. ( Abbasi, A; Dehpour, AR; Fakhfouri, G; Fakhraei, N; Ghia, JE; Heydarpour, P; Khoshkish, S; Rahimian, R; Salehi-Sadaghiani, M; Wang, H, 2016) |
| "TNF-α-colitis was characterized by hemorrhagic edemas and crypt abscesses massively infiltrated by inflammatory cells, namely neutrophils." | 1.38 | Aminoguanidine and curcumin attenuated tumor necrosis factor (TNF)-α-induced oxidative stress, colitis and hepatotoxicity in mice. ( Djerdjouri, B; Mouzaoui, S; Rahim, I, 2012) |
| "Colitis was induced by 4% DSS in drinking water, in rats pretreated with L-NAME or aminoguanidine." | 1.34 | Modulatory effect of nitric oxide on mast cells during induction of dextran sulfate sodium colitis. ( Guarner, F; Malagelada, JR; Medina, C; Mourelle, M; Salas, A; Videla, S; Vilaseca, J, 2007) |
| "Rats treated with rofecoxib, aminoguanidine hydrochloride and their combinations reduced the inflammation, acute colonic damage produced by TNBS as verified by macroscopic changes in colon." | 1.34 | Influence of simultaneous inhibition of cyclooxygenase-2 and inducible nitric oxide synthase in experimental colitis in rats. ( Dudhgaonkar, SP; Kataria, M; Kumar, D; Raviprakash, V; Tandan, SK, 2007) |
| "TNB-colitis was induced in rats with and without pretreatment with AG (200 mg kg-1 body weight in the drinking water)." | 1.31 | Inhibition of nitric oxide synthesis by aminoguanidine increases intestinal damage in the acute phase of rat TNB-colitis. ( Adler, G; Bachem, M; Dikopoulos, N; Liptay, S; Nüssler, AK; Reinshagen, M; Schmid, RM; Stiegler, M; Weidenbach, H, 2001) |
| "Excess nitric oxide formation caused by the activity of the inducible nitric oxide synthase has been implicated as a toxic effector molecule in the pathogenesis of experimental colitis and inflammatory bowel disease." | 1.30 | Interferon-gamma (IFN-gamma)- and tumour necrosis factor (TNF)-induced nitric oxide as toxic effector molecule in chronic dextran sulphate sodium (DSS)-induced colitis in mice. ( Falk, W; Gross, V; Hans, W; Kojouharoff, G; Obermeier, F; Schölmerich, J, 1999) |
| "Colitis was induced by means of trinitrobenzene sulphonic acid (TNB) in male Wistar rats weighing about 250 g." | 1.30 | Aminoguanidine has both an anti-inflammatory effect on experimental colitis and a proliferative effect on colonic mucosal cells. ( Fukuda, K; Hosokawa, M; Kodama, M; Nakamura, H; Onomura, M; Oya, M; Saito, T; Seino, Y; Taniguchi, T; Tominaga, M; Tsukada, H, 1999) |
| "Acute inflammation was associated with enlarged colonic perimeter." | 1.29 | Toxic dilatation of colon in a rat model of colitis is linked to an inducible form of nitric oxide synthase. ( Guarner, F; Malagelada, JR; Mourelle, M; Salas, A; Vilaseca, J, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (21.43) | 18.2507 |
| 2000's | 6 (42.86) | 29.6817 |
| 2010's | 4 (28.57) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Shahraki, FN | 1 |
| Momtaz, S | 1 |
| Baeeri, M | 1 |
| Khayatan, D | 1 |
| Lashgari, NA | 1 |
| Roudsari, NM | 1 |
| Abdollahi, AR | 1 |
| Dehpour, AR | 3 |
| Abdolghaffari, AH | 1 |
| Farghaly, HS | 1 |
| Thabit, RH | 1 |
| Gharedaghi, MH | 1 |
| Rahimian, R | 2 |
| Yousefzadeh-Fard, Y | 1 |
| Mohammadi-Farani, A | 1 |
| Heydarpour, P | 1 |
| Fakhfouri, G | 1 |
| Khoshkish, S | 1 |
| Fakhraei, N | 1 |
| Salehi-Sadaghiani, M | 1 |
| Wang, H | 1 |
| Abbasi, A | 1 |
| Ghia, JE | 1 |
| Ercin, CN | 1 |
| Yesilova, Z | 1 |
| Korkmaz, A | 1 |
| Ozcan, A | 1 |
| Oktenli, C | 1 |
| Uygun, A | 1 |
| Mouzaoui, S | 1 |
| Rahim, I | 1 |
| Djerdjouri, B | 1 |
| Rumi, G | 1 |
| Tsubouchi, R | 1 |
| Nishio, H | 1 |
| Kato, S | 1 |
| Mózsik, G | 1 |
| Takeuchi, K | 1 |
| Videla, S | 1 |
| Vilaseca, J | 2 |
| Medina, C | 1 |
| Mourelle, M | 2 |
| Guarner, F | 2 |
| Salas, A | 2 |
| Malagelada, JR | 2 |
| Dudhgaonkar, SP | 1 |
| Tandan, SK | 1 |
| Kumar, D | 1 |
| Raviprakash, V | 1 |
| Kataria, M | 1 |
| Obermeier, F | 1 |
| Kojouharoff, G | 1 |
| Hans, W | 1 |
| Schölmerich, J | 1 |
| Gross, V | 1 |
| Falk, W | 1 |
| Nakamura, H | 1 |
| Tsukada, H | 1 |
| Oya, M | 1 |
| Onomura, M | 1 |
| Saito, T | 1 |
| Fukuda, K | 1 |
| Kodama, M | 1 |
| Taniguchi, T | 1 |
| Tominaga, M | 1 |
| Hosokawa, M | 1 |
| Seino, Y | 1 |
| Dikopoulos, N | 1 |
| Nüssler, AK | 1 |
| Liptay, S | 1 |
| Bachem, M | 1 |
| Reinshagen, M | 1 |
| Stiegler, M | 1 |
| Schmid, RM | 1 |
| Adler, G | 1 |
| Weidenbach, H | 1 |
| Bossone, C | 1 |
| Hosseini, JM | 1 |
| Piñeiro-Carrero, V | 1 |
| Shea-Donohue, T | 1 |
14 other studies available for pimagedine and Colitis
| Article | Year |
|---|---|
Licofelone Attenuates Acetic Acid-Induced Colitis in Rats Through Suppression of the Inflammatory Mediators.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Colitis; Colitis, Ulcerative; Inflammation Mediators | 2023 |
L-arginine and aminoguanidine reduce colonic damage of acetic acid-induced colitis in rats: potential modulation of nuclear factor-κB/p65.
Topics: Acetic Acid; Animals; Arginine; Body Weight; Colitis; Colon; Guanidines; Inflammation; Male; NF-kapp | 2014 |
Dinitrobenzene sulphonic acid-induced colitis impairs spatial recognition memory in mice: roles of N-methyl D-aspartate receptors and nitric oxide.
Topics: Animals; Avoidance Learning; Benzenesulfonates; Cognition; Colitis; Dizocilpine Maleate; Guanidines; | 2015 |
Behavioral despair associated with a mouse model of Crohn's disease: Role of nitric oxide pathway.
Topics: Animals; Antidepressive Agents; Colitis; Colon; Crohn Disease; Depression; Disease Models, Animal; E | 2016 |
The effect of iNOS inhibitors and hyperbaric oxygen treatment in a rat model of experimental colitis.
Topics: Acetic Acid; Animals; Colitis; Combined Modality Therapy; Disease Models, Animal; Female; Guanidines | 2009 |
Aminoguanidine and curcumin attenuated tumor necrosis factor (TNF)-α-induced oxidative stress, colitis and hepatotoxicity in mice.
Topics: Animals; Antioxidants; Apoptosis; Colitis; Curcumin; Guanidines; Liver; Male; Mice; Neutrophils; Nit | 2012 |
Dual role of endogenous nitric oxide in development of dextran sodium sulfate-induced colitis in rats.
Topics: Animals; Colitis; Dextran Sulfate; Guanidines; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Ni | 2004 |
Modulatory effect of nitric oxide on mast cells during induction of dextran sulfate sodium colitis.
Topics: Animals; Colitis; Dextran Sulfate; Guanidines; Intestinal Mucosa; Ketotifen; Male; Mast Cells; NG-Ni | 2007 |
Influence of simultaneous inhibition of cyclooxygenase-2 and inducible nitric oxide synthase in experimental colitis in rats.
Topics: Animals; Catalase; Colitis; Colon; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Drug Therapy, Comb | 2007 |
Toxic dilatation of colon in a rat model of colitis is linked to an inducible form of nitric oxide synthase.
Topics: Animals; Arginine; Colitis; Colon; Dexamethasone; Dilatation; Disease Models, Animal; Enzyme Inducti | 1996 |
Interferon-gamma (IFN-gamma)- and tumour necrosis factor (TNF)-induced nitric oxide as toxic effector molecule in chronic dextran sulphate sodium (DSS)-induced colitis in mice.
Topics: Animals; Colitis; Dextran Sulfate; Female; Guanidines; Interferon-gamma; Mice; Mice, Inbred BALB C; | 1999 |
Aminoguanidine has both an anti-inflammatory effect on experimental colitis and a proliferative effect on colonic mucosal cells.
Topics: Analysis of Variance; Animals; Colitis; Enzyme Inhibitors; Epithelial Cells; Guanidines; Intestinal | 1999 |
Inhibition of nitric oxide synthesis by aminoguanidine increases intestinal damage in the acute phase of rat TNB-colitis.
Topics: Acute Disease; Animals; Colitis; Colon; Guanidines; Liver; Male; Neutrophil Infiltration; NF-kappa B | 2001 |
Alterations in spontaneous contractions in vitro after repeated inflammation of rat distal colon.
Topics: Animals; Colitis; Colon; Disease Models, Animal; Gastrointestinal Motility; Guanidines; In Vitro Tec | 2001 |