pimagedine has been researched along with Clinically Isolated CNS Demyelinating Syndrome in 4 studies
pimagedine: diamine oxidase & nitric oxide synthase inhibitor; an advanced glycosylation end product inhibitor; used in the treatment of diabetic complications; structure
aminoguanidine : A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Inflammation, demyelination and axonal necrosis were scored in a blinded fashion on spinal cord sections from each mouse." | 1.30 | Nitric oxide synthase inhibitor, aminoguanidine, reduces inflammation and demyelination produced by Theiler's virus infection. ( Cross, AH; Fujinami, RS; Hill, KE; Kurtz, CI; Rose, JW; Tsunoda, I; Wada, Y, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rose, JW | 1 |
| Hill, KE | 1 |
| Wada, Y | 1 |
| Kurtz, CI | 1 |
| Tsunoda, I | 1 |
| Fujinami, RS | 1 |
| Cross, AH | 1 |
| Lane, TE | 1 |
| Fox, HS | 1 |
| Buchmeier, MJ | 1 |
| Iwahashi, T | 1 |
| Inoue, A | 1 |
| Koh, CS | 1 |
| Shin, TK | 1 |
| Kim, BS | 1 |
| Pozza, M | 1 |
| Bettelli, C | 1 |
| Aloe, L | 1 |
| Giardino, L | 1 |
| Calzà, L | 1 |
4 other studies available for pimagedine and Clinically Isolated CNS Demyelinating Syndrome
| Article | Year |
|---|---|
Nitric oxide synthase inhibitor, aminoguanidine, reduces inflammation and demyelination produced by Theiler's virus infection.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Axons; Demyelinating Diseases; DNA Frag | 1998 |
Inhibition of nitric oxide synthase-2 reduces the severity of mouse hepatitis virus-induced demyelination: implications for NOS2/NO regulation of chemokine expression and inflammation.
Topics: Animals; Brain; Chemokine CCL2; Chemokines; Coronavirus Infections; Demyelinating Diseases; Enzyme I | 1999 |
Expression and potential role of inducible nitric oxide synthase in the central nervous system of Theiler's murine encephalomyelitis virus-induced demyelinating disease.
Topics: Animals; Cardiovirus Infections; Cell Line; Central Nervous System; Cricetinae; Cytokines; Demyelina | 1999 |
Further evidence for a role of nitric oxide in experimental allergic encephalomyelitis: aminoguanidine treatment modifies its clinical evolution.
Topics: Acute Disease; Animals; Brain; Demyelinating Diseases; Disease Progression; Encephalomyelitis, Autoi | 2000 |