pimagedine has been researched along with Cirrhoses, Experimental Liver in 8 studies
pimagedine: diamine oxidase & nitric oxide synthase inhibitor; an advanced glycosylation end product inhibitor; used in the treatment of diabetic complications; structure
aminoguanidine : A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our aim was to evaluate NO role in renal failure induced during decompensated cirrhosis, using the following inhibitors: aminoguanidine (AG), a specific inducible nitric oxide synthase (iNOS) inhibitor and NG-nitro-l-arginine methyl ester (L-NAME), a nonselective blocker of NOS isoforms." | 1.33 | Nitric oxide synthases inhibition results in renal failure improvement in cirrhotic rats. ( Alvarez-Rodríguez, A; Armendáriz-Borunda, J; Covarrubias, A; Grijalva, G; Islas-Carbajal, MC; Rincón-Sánchez, AR, 2005) |
| " Chronic administration of AG did not modify significantly any parameter in cirrhotic and control animals." | 1.31 | [Renal effects of the chronic inhibition of nitric oxide synthesis in cirrhotic rats with ascites]. ( Atucha, NM; Eleno, N; Fortepiani, LA; García-Estañ, J; López-Novoa, JM; Martínez-Salgado, C; Ortiz, MC, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 6 (75.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Doğru-Abbasoğlu, S | 1 |
| Balkan, J | 1 |
| Kanbağli, O | 1 |
| Cevikbaş, U | 1 |
| Aykaç-Toker, G | 1 |
| Uysal, M | 1 |
| Islas-Carbajal, MC | 1 |
| Covarrubias, A | 1 |
| Grijalva, G | 1 |
| Alvarez-Rodríguez, A | 1 |
| Armendáriz-Borunda, J | 1 |
| Rincón-Sánchez, AR | 1 |
| Gao, FS | 1 |
| Liu, B | 1 |
| Zhan, YT | 1 |
| Shi, XL | 1 |
| Zhang, JX | 1 |
| Wang, N | 1 |
| Ding, Y | 1 |
| Xie, XJ | 1 |
| Zhang, HY | 1 |
| Han, DW | 1 |
| Su, AR | 1 |
| Zhang, LT | 1 |
| Zhao, ZF | 1 |
| Ji, JQ | 1 |
| Li, BH | 1 |
| Ji, C | 1 |
| Ortíz, MC | 3 |
| Fortepiani, LA | 2 |
| Martínez, C | 1 |
| Atucha, NM | 3 |
| García-Estañ, J | 3 |
| Criado, M | 1 |
| Flores, O | 1 |
| Hidalgo, F | 1 |
| Rodríguez-López, AM | 1 |
| Eleno, N | 2 |
| Sánchez-Rodríguez, A | 1 |
| Arévalo, M | 1 |
| López-Novoa, JM | 2 |
| Schmandra, TC | 1 |
| Folz, IC | 1 |
| Kimpel, M | 1 |
| Fleming, I | 1 |
| Holzer, K | 1 |
| Hanisch, EW | 1 |
| Martínez-Salgado, C | 1 |
8 other studies available for pimagedine and Cirrhoses, Experimental Liver
| Article | Year |
|---|---|
Aminoguanidine, an inducible nitric oxide synthase inhibitor, plus N-acetylcysteine treatment reduce the lipopolysaccharide-augmented hepatotoxicity in rats with cirrhosis.
Topics: Acetylcysteine; Analysis of Variance; Animals; Free Radical Scavengers; Guanidines; Lipopolysacchari | 2002 |
Nitric oxide synthases inhibition results in renal failure improvement in cirrhotic rats.
Topics: Animals; Aspartate Aminotransferases; Creatinine; Disease Models, Animal; Enzyme Inhibitors; Guanidi | 2005 |
[The changes of advanced glycation end products in a rat liver fibrosis model and the interventional effect of aminoguanidin].
Topics: Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Glycation End Products, Advanced; Gua | 2006 |
Intestinal endotoxemia plays a central role in development of hepatopulmonary syndrome in a cirrhotic rat model induced by multiple pathogenic factors.
Topics: Alanine Transaminase; Animals; Bronchoalveolar Lavage Fluid; Capillaries; Carboxyhemoglobin; Cytokin | 2007 |
Renal and pressor effects of aminoguanidine in cirrhotic rats with ascites.
Topics: Animals; Ascites; Blood Pressure; Enzyme Inhibitors; Guanidines; Kidney; Liver Cirrhosis, Experiment | 1996 |
Elevated glomerular and blood mononuclear lymphocyte nitric oxide production in rats with chronic bile duct ligation: role of inducible nitric oxide synthase activation.
Topics: Animals; Chronic Disease; Enzyme Activation; Guanidines; Kidney Glomerulus; Liver Cirrhosis, Experim | 1997 |
Cirrhosis serum induces a nitric oxide-associated vascular hyporeactivity of aortic segments from healthy rats in vitro.
Topics: Animals; Aorta; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanidines; In Vitro Techniques | 2001 |
[Renal effects of the chronic inhibition of nitric oxide synthesis in cirrhotic rats with ascites].
Topics: Animals; Ascites; Blood Pressure; Carbon Tetrachloride; Diuresis; Glomerular Filtration Rate; Guanid | 2001 |