pimagedine has been researched along with Chronic Kidney Failure in 13 studies
pimagedine: diamine oxidase & nitric oxide synthase inhibitor; an advanced glycosylation end product inhibitor; used in the treatment of diabetic complications; structure
aminoguanidine : A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.
| Excerpt | Relevance | Reference |
|---|---|---|
| " During the interdialytic period, the maximum aminoguanidine concentration (Cmax) and time to reach Cmax was 4." | 2.68 | The pharmacokinetics of aminoguanidine in end-stage renal disease patients on hemodialysis. ( Foote, EF; Giles, P; Halstenson, CE; Keane, WF; Look, ZM, 1995) |
| "Renal functional decline in diabetic nephropathy is slowed by establishment of euglycaemia and normalization of hypertensive blood pressure." | 2.40 | Advanced glycation end-products in diabetic nephropathy. ( Friedman, EA, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (61.54) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 2 (15.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, S | 1 |
| Li, B | 1 |
| Li, C | 1 |
| Cui, W | 1 |
| Miao, L | 1 |
| Tomino, Y | 1 |
| Inagi, R | 1 |
| Miyata, T | 1 |
| Ueda, Y | 1 |
| Yoshino, A | 1 |
| Nangaku, M | 1 |
| van Ypersele de Strihou, C | 1 |
| Kurokawa, K | 1 |
| Foote, EF | 1 |
| Look, ZM | 1 |
| Giles, P | 1 |
| Keane, WF | 1 |
| Halstenson, CE | 1 |
| Bucala, R | 1 |
| Makita, Z | 1 |
| Vega, G | 1 |
| Grundy, S | 1 |
| Koschinsky, T | 1 |
| Cerami, A | 1 |
| Vlassara, H | 1 |
| Friedman, EA | 3 |
| Distant, DA | 1 |
| Fleishhacker, JF | 1 |
| Boyd, TA | 1 |
| Cartwright, K | 2 |
| Brooks, DP | 1 |
| Contino, LC | 1 |
| Weiss, MF | 2 |
| Saxena, AK | 1 |
| Monnier, VM | 2 |
| Freedman, BI | 1 |
| Wuerth, JP | 1 |
| Bain, RP | 1 |
| Dippe, S | 1 |
| Hershon, K | 1 |
| Mooradian, AD | 1 |
| Spinowitz, BS | 1 |
| Erhard, P | 1 |
| Kader-Attia, FA | 1 |
| Wu, YC | 1 |
| Deoreo, PB | 1 |
| Araki, A | 1 |
| Glomb, MA | 1 |
| Nohara, Y | 1 |
| Usui, T | 1 |
| Kinoshita, T | 1 |
| Watanabe, M | 1 |
4 reviews available for pimagedine and Chronic Kidney Failure
| Article | Year |
|---|---|
Potential Renoprotective Agents through Inhibiting CTGF/CCN2 in Diabetic Nephropathy.
Topics: Animals; Anthocyanins; Antibodies, Monoclonal; Connective Tissue Growth Factor; Diabetes Mellitus; D | 2015 |
Mechanisms and interventions in peritoneal fibrosis.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Epithelial Cell | 2012 |
Will pimagidine improve survival of diabetics on dialysis?
Topics: Arteriosclerosis; Diabetes Complications; Diabetes Mellitus; Glycation End Products, Advanced; Guani | 1996 |
Advanced glycation end-products in diabetic nephropathy.
Topics: Animals; Diabetic Nephropathies; Enzyme Inhibitors; Female; Glucose; Glycation End Products, Advance | 1999 |
3 trials available for pimagedine and Chronic Kidney Failure
| Article | Year |
|---|---|
The pharmacokinetics of aminoguanidine in end-stage renal disease patients on hemodialysis.
Topics: Diabetic Nephropathies; Female; Guanidines; Half-Life; Humans; Kidney; Kidney Failure, Chronic; Male | 1995 |
Modification of low density lipoprotein by advanced glycation end products contributes to the dyslipidemia of diabetes and renal insufficiency.
Topics: Animals; Cholesterol; Diabetes Mellitus; Diabetic Nephropathies; Enzyme-Linked Immunosorbent Assay; | 1994 |
Design and baseline characteristics for the aminoguanidine Clinical Trial in Overt Type 2 Diabetic Nephropathy (ACTION II).
Topics: Adult; Aged; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Double-Blind Method; Drug Administra | 1999 |
6 other studies available for pimagedine and Chronic Kidney Failure
| Article | Year |
|---|---|
Efficient in vitro lowering of carbonyl stress by the glyoxalase system in conventional glucose peritoneal dialysis fluid.
Topics: Animals; CHO Cells; Cricetinae; Deoxyglucose; Dialysis Solutions; Gene Expression Regulation, Enzymo | 2002 |
Aminoguanidine prolongs survival in azotemic-induced diabetic rats.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Enzyme Inhibitors; Glycation End P | 1997 |
Involvement of nitric oxide synthase in proteinuria associated with chronic renal disease in rats.
Topics: Animals; Blood Pressure; Blood Urea Nitrogen; Creatinine; Enzyme Inhibitors; Guanidines; Kidney Fail | 1998 |
Pharmacological modulation of AGEs: a unique role for redox-active metal ions.
Topics: Animals; Antioxidants; Chelating Agents; Diabetes Mellitus; Glycation End Products, Advanced; Guanid | 1999 |
Mechanisms for the formation of glycoxidation products in end-stage renal disease.
Topics: Adult; Aged; Aged, 80 and over; Arginine; Enzyme Inhibitors; Female; Glucose; Glycation End Products | 2000 |
Generation of superoxide anions during the reaction of guanidino compounds with methylglyoxal.
Topics: Guanidine; Guanidines; Humans; Kidney Failure, Chronic; Oxidative Stress; Pyruvaldehyde; Superoxides | 2002 |