pimagedine has been researched along with Chronic Illness in 15 studies
pimagedine: diamine oxidase & nitric oxide synthase inhibitor; an advanced glycosylation end product inhibitor; used in the treatment of diabetic complications; structure
aminoguanidine : A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Glaucoma is an optic neuropathy with cupping of the optic disk, degeneration of retinal ganglion cells, and characteristic visual field loss." | 1.30 | Inhibition of nitric-oxide synthase 2 by aminoguanidine provides neuroprotection of retinal ganglion cells in a rat model of chronic glaucoma. ( Becker, B; Neufeld, AH; Sawada, A, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (26.67) | 18.2507 |
| 2000's | 10 (66.67) | 29.6817 |
| 2010's | 1 (6.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tinker, AC | 1 |
| Beaton, HG | 1 |
| Boughton-Smith, N | 1 |
| Cook, TR | 1 |
| Cooper, SL | 1 |
| Fraser-Rae, L | 1 |
| Hallam, K | 1 |
| Hamley, P | 1 |
| McInally, T | 1 |
| Nicholls, DJ | 1 |
| Pimm, AD | 1 |
| Wallace, AV | 1 |
| Franchin, M | 1 |
| Colón, DF | 1 |
| da Cunha, MG | 1 |
| Castanheira, FV | 1 |
| Saraiva, AL | 1 |
| Bueno-Silva, B | 1 |
| Alencar, SM | 1 |
| Cunha, TM | 1 |
| Rosalen, PL | 1 |
| Botha, T | 1 |
| Ryffel, B | 1 |
| Uesaka, Y | 1 |
| Ibáñez de Cáceres, I | 1 |
| Priego, T | 1 |
| Martín, AI | 1 |
| López-Calderón, A | 1 |
| Villanúa, MA | 1 |
| Coney, AM | 1 |
| Bishay, M | 1 |
| Marshall, JM | 1 |
| Fike, CD | 1 |
| Aschner, JL | 1 |
| Zhang, Y | 1 |
| Kaplowitz, MR | 1 |
| Senaratne, RH | 1 |
| De Silva, AD | 1 |
| Williams, SJ | 1 |
| Mougous, JD | 1 |
| Reader, JR | 1 |
| Zhang, T | 1 |
| Chan, S | 1 |
| Sidders, B | 1 |
| Lee, DH | 1 |
| Chan, J | 2 |
| Bertozzi, CR | 1 |
| Riley, LW | 1 |
| Tufariello, JM | 1 |
| Mi, K | 1 |
| Xu, J | 1 |
| Manabe, YC | 1 |
| Kesavan, AK | 1 |
| Drumm, J | 1 |
| Tanaka, K | 1 |
| Jacobs, WR | 1 |
| Biketov, S | 1 |
| Potapov, V | 1 |
| Ganina, E | 1 |
| Downing, K | 1 |
| Kana, BD | 1 |
| Kaprelyants, A | 1 |
| Wang, D | 1 |
| An, SC | 1 |
| Zhang, X | 1 |
| Grisham, MB | 1 |
| Specian, RD | 1 |
| Zimmerman, TE | 1 |
| Criado, M | 1 |
| Flores, O | 1 |
| Ortíz, MC | 1 |
| Hidalgo, F | 1 |
| Rodríguez-López, AM | 1 |
| Eleno, N | 1 |
| Atucha, NM | 1 |
| Sánchez-Rodríguez, A | 1 |
| Arévalo, M | 1 |
| Garcia-Estañ, J | 1 |
| López-Novoa, JM | 1 |
| Neufeld, AH | 1 |
| Sawada, A | 1 |
| Becker, B | 1 |
| Niwa, K | 1 |
| Takizawa, S | 1 |
| Kawaguchi, C | 1 |
| Kamiya, U | 1 |
| Kuwahira, I | 1 |
| Shinohara, Y | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized Controlled Trial Of The Effect Of Tropical Fruits On Intraocular Pressure And Retinal Nerve Fibre Layer Thickness In Patients With Primary Glaucoma[NCT06071494] | 102 participants (Anticipated) | Interventional | 2023-10-01 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for pimagedine and Chronic Illness
| Article | Year |
|---|---|
[Prevention and treatment of diabetic neuropathy].
Topics: Aldehyde Reductase; Angiotensin-Converting Enzyme Inhibitors; Antioxidants; Chronic Disease; Diabeti | 2002 |
14 other studies available for pimagedine and Chronic Illness
| Article | Year |
|---|---|
1,2-Dihydro-4-quinazolinamines: potent, highly selective inhibitors of inducible nitric oxide synthase which show antiinflammatory activity in vivo.
Topics: Acute Disease; Administration, Oral; Amines; Animals; Arthritis, Experimental; Cell Line; Chronic Di | 2003 |
Neovestitol, an isoflavonoid isolated from Brazilian red propolis, reduces acute and chronic inflammation: involvement of nitric oxide and IL-6.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Brazil; CD4-Positive T-Ly | 2016 |
Reactivation of latent tuberculosis by an inhibitor of inducible nitric oxide synthase in an aerosol murine model.
Topics: Animals; Antitubercular Agents; Chronic Disease; Disease Models, Animal; Enzyme Inhibitors; Guanidin | 2002 |
The inhibition of inducible nitric oxide synthase reverts arthritic-induced decrease in pituitary growth hormone mRNA but not in liver insulin-like growth factor I mRNA expression.
Topics: Animals; Arthritis, Experimental; Chronic Disease; Enzyme Inhibitors; Gene Expression; Growth Hormon | 2003 |
Influence of endogenous nitric oxide on sympathetic vasoconstriction in normoxia, acute and chronic systemic hypoxia in the rat.
Topics: Acute Disease; Animals; Chronic Disease; Electric Stimulation; Enzyme Inhibitors; Guanidines; Hindli | 2004 |
Impaired NO signaling in small pulmonary arteries of chronically hypoxic newborn piglets.
Topics: Animals; Animals, Newborn; Caveolin 1; Caveolins; Chronic Disease; Enzyme Inhibitors; Guanidines; HS | 2004 |
5'-Adenosinephosphosulphate reductase (CysH) protects Mycobacterium tuberculosis against free radicals during chronic infection phase in mice.
Topics: Animals; Bacterial Proteins; Chronic Disease; Cysteine; Enzyme Inhibitors; Free Radicals; Genes, Bac | 2006 |
Deletion of the Mycobacterium tuberculosis resuscitation-promoting factor Rv1009 gene results in delayed reactivation from chronic tuberculosis.
Topics: Animals; B-Lymphocytes; Bacterial Proteins; Chronic Disease; Cytokines; Female; Guanidines; Lung; Mi | 2006 |
The role of resuscitation promoting factors in pathogenesis and reactivation of Mycobacterium tuberculosis during intra-peritoneal infection in mice.
Topics: Animals; Antibodies, Monoclonal; Bacterial Proteins; Chronic Disease; Cytokines; Disease Models, Ani | 2007 |
Prevention of chronic stress-induced depression-like behavior by inducible nitric oxide inhibitor.
Topics: Animals; Appetite; Behavior, Animal; Body Weight; Chronic Disease; Depressive Disorder; Disease Mode | 2008 |
Effects of nitric oxide synthase inhibition on the pathophysiology observed in a model of chronic granulomatous colitis.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Chronic Disease; Crohn Disease; Femal | 1994 |
Elevated glomerular and blood mononuclear lymphocyte nitric oxide production in rats with chronic bile duct ligation: role of inducible nitric oxide synthase activation.
Topics: Animals; Chronic Disease; Enzyme Activation; Guanidines; Kidney Glomerulus; Liver Cirrhosis, Experim | 1997 |
Inhibition of nitric-oxide synthase 2 by aminoguanidine provides neuroprotection of retinal ganglion cells in a rat model of chronic glaucoma.
Topics: Animals; Chronic Disease; Enzyme Inhibitors; Glaucoma; Guanidines; Humans; Intraocular Pressure; Mal | 1999 |
Expression of inducible nitric oxide synthase immunoreactivity in rat brain following chronic hypoxia: effect of aminoguanidine.
Topics: Animals; Brain; Chronic Disease; Enzyme Inhibitors; Guanidines; Hypoxia, Brain; Male; Neovasculariza | 1999 |