pimagedine has been researched along with Cerebrovascular Disorders in 1 studies
pimagedine: diamine oxidase & nitric oxide synthase inhibitor; an advanced glycosylation end product inhibitor; used in the treatment of diabetic complications; structure
aminoguanidine : A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.
Cerebrovascular Disorders: A spectrum of pathological conditions of impaired blood flow in the brain. They can involve vessels (ARTERIES or VEINS) in the CEREBRUM, the CEREBELLUM, and the BRAIN STEM. Major categories include INTRACRANIAL ARTERIOVENOUS MALFORMATIONS; BRAIN ISCHEMIA; CEREBRAL HEMORRHAGE; and others.
| Excerpt | Relevance | Reference |
|---|---|---|
| "During a cerebral infarction, a complex cascade of cytotoxic events ultimately determines the volume of brain cell loss." | 1.29 | Cerebroprotective effects of aminoguanidine in a rodent model of stroke. ( Bloom, O; Cerami, A; Cockroft, KM; Meistrell, M; Risucci, D; Tracey, KJ; Zimmerman, GA, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cockroft, KM | 1 |
| Meistrell, M | 1 |
| Zimmerman, GA | 1 |
| Risucci, D | 1 |
| Bloom, O | 1 |
| Cerami, A | 1 |
| Tracey, KJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase II Study of the Effects of Tiopronin on 3-Aminopropanal Level & Neurologic Outcome After Aneurysmal Subarachnoid Hemorrhage[NCT01095731] | Phase 2 | 60 participants (Actual) | Interventional | 2010-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 other study available for pimagedine and Cerebrovascular Disorders
| Article | Year |
|---|---|
Cerebroprotective effects of aminoguanidine in a rodent model of stroke.
Topics: Animals; Cerebral Infarction; Cerebrovascular Circulation; Cerebrovascular Disorders; Disease Models | 1996 |