Page last updated: 2024-10-22

pimagedine and Brain Vascular Disorders

pimagedine has been researched along with Brain Vascular Disorders in 1 studies

pimagedine: diamine oxidase & nitric oxide synthase inhibitor; an advanced glycosylation end product inhibitor; used in the treatment of diabetic complications; structure
aminoguanidine : A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.

Research Excerpts

Excerpt	Relevance	Reference
"During a cerebral infarction, a complex cascade of cytotoxic events ultimately determines the volume of brain cell loss."	1.29	Cerebroprotective effects of aminoguanidine in a rodent model of stroke. ( Bloom, O; Cerami, A; Cockroft, KM; Meistrell, M; Risucci, D; Tracey, KJ; Zimmerman, GA, 1996)

Research

Studies (1)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (100.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Cockroft, KM	1
Meistrell, M	1
Zimmerman, GA	1
Risucci, D	1
Bloom, O	1
Cerami, A	1
Tracey, KJ	1

Clinical Trials (1)

Trial Overview

Trial			Phase	Enrollment	Study Type	Start Date	Status
Phase II Study of the Effects of Tiopronin on 3-Aminopropanal Level & Neurologic Outcome After Aneurysmal Subarachnoid Hemorrhage[NCT01095731]			Phase 2	60 participants (Actual)	Interventional	2010-04-30	Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

1 other study available for pimagedine and Brain Vascular Disorders

Article	Year
Cerebroprotective effects of aminoguanidine in a rodent model of stroke. Stroke, 1996, Volume: 27, Issue:8 Topics: Animals; Cerebral Infarction; Cerebrovascular Circulation; Cerebrovascular Disorders; Disease Models	1996