pimagedine has been researched along with Brain Edema in 7 studies
pimagedine: diamine oxidase & nitric oxide synthase inhibitor; an advanced glycosylation end product inhibitor; used in the treatment of diabetic complications; structure
aminoguanidine : A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.
Brain Edema: Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (85.71) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Di, F | 1 |
| Yan-Ting, G | 1 |
| Hui, L | 1 |
| Tao, T | 1 |
| Zai-Hua, X | 1 |
| Xue-Ying, S | 1 |
| Hong-Li, X | 1 |
| Yun-Jie, W | 1 |
| Hao, W | 1 |
| Wu, XQ | 1 |
| Xu, RT | 1 |
| Sun, M | 1 |
| Zhao, Y | 1 |
| Gu, Y | 1 |
| Xu, C | 1 |
| Louin, G | 1 |
| Marchand-Verrecchia, C | 1 |
| Palmier, B | 1 |
| Plotkine, M | 1 |
| Jafarian-Tehrani, M | 1 |
| Vakili, A | 1 |
| Hosseinzadeh, F | 1 |
| Sadogh, T | 1 |
| Demougeot, C | 1 |
| Garnier, P | 1 |
| Mossiat, C | 1 |
| Bertrand, N | 1 |
| Giroud, M | 1 |
| Beley, A | 1 |
| Marie, C | 1 |
| Stoffel, M | 1 |
| Rinecker, M | 1 |
| Plesnila, N | 1 |
| Eriskat, J | 1 |
| Baethmann, A | 1 |
7 other studies available for pimagedine and Brain Edema
| Article | Year |
|---|---|
Role of aminoguanidine in brain protection in surgical brain injury in rat.
Topics: Animals; Blood-Brain Barrier; Blotting, Western; Brain; Brain Chemistry; Brain Edema; Brain Injuries | 2008 |
The molecular mechanism of aminoguanidine-mediated reduction on the brain edema after surgical brain injury in rats.
Topics: Animals; Aquaporin 4; Brain Edema; Brain Injuries; Disease Models, Animal; Dose-Response Relationshi | 2009 |
Neuroprotective actions of aminoguanidine involve reduced the activation of calpain and caspase-3 in a rat model of stroke.
Topics: Animals; Apoptosis; Biotransformation; Blotting, Western; Brain; Brain Edema; Calcium-Binding Protei | 2010 |
Selective inhibition of inducible nitric oxide synthase reduces neurological deficit but not cerebral edema following traumatic brain injury.
Topics: Amidines; Animals; Benzylamines; Blood-Brain Barrier; Body Water; Brain Edema; Brain Injuries; Enzym | 2006 |
Effect of aminoguanidine on post-ischemic brain edema in transient model of focal cerebral ischemia.
Topics: Animals; Blood-Brain Barrier; Brain Edema; Brain Infarction; Cerebral Arteries; Coloring Agents; Dos | 2007 |
N-Acetylaspartate, a marker of both cellular dysfunction and neuronal loss: its relevance to studies of acute brain injury.
Topics: 2,2'-Dipyridyl; Acute Disease; Animals; Aspartic Acid; Biomarkers; Brain Chemistry; Brain Edema; Bra | 2001 |
Attenuation of secondary lesion growth in the brain after trauma by selective inhibition of the inducible NO-synthase.
Topics: Animals; Brain Damage, Chronic; Brain Edema; Brain Injuries; Cerebral Cortex; Enzyme Inhibitors; Gua | 2000 |