pimagedine has been researched along with Bone Loss, Osteoclastic in 5 studies
pimagedine: diamine oxidase & nitric oxide synthase inhibitor; an advanced glycosylation end product inhibitor; used in the treatment of diabetic complications; structure
aminoguanidine : A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this study, we evaluate the alveolar bone loss in rats with periodontitis under long-term iNOS inhibition, and the differentiation and activity of OC from iNOS-knockout (KO) mice in vitro." | 1.37 | iNOS-derived nitric oxide stimulates osteoclast activity and alveolar bone loss in ligature-induced periodontitis in rats. ( Campi, P; Costa, SK; Gyurko, R; Herrera, BS; Maia-Dantas, A; Martins-Porto, R; Muscara, MN; Spolidorio, LC; Van Dyke, TE, 2011) |
| "A murine model of cholesteatoma induced bone resorption was used to demonstrate nitric oxide synthase (NOS) gene expression and the effect of a NOS inhibitor." | 1.32 | A possible role for nitric oxide in osteoclastogenesis associated with cholesteatoma. ( Chole, RA; Faddis, BT; Jung, JY; Nishimoto, SY; Pashia, ME, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Herrera, BS | 1 |
| Martins-Porto, R | 1 |
| Maia-Dantas, A | 1 |
| Campi, P | 1 |
| Spolidorio, LC | 1 |
| Costa, SK | 1 |
| Van Dyke, TE | 1 |
| Gyurko, R | 1 |
| Muscara, MN | 1 |
| Jung, JY | 1 |
| Pashia, ME | 1 |
| Nishimoto, SY | 1 |
| Faddis, BT | 1 |
| Chole, RA | 1 |
| Holliday, LS | 1 |
| Dean, AD | 1 |
| Lin, RH | 1 |
| Greenwald, JE | 1 |
| Gluck, SL | 1 |
| Collin-Osdoby, P | 1 |
| Rothe, L | 1 |
| Bekker, S | 1 |
| Anderson, F | 1 |
| Osdoby, P | 1 |
| Schurman, L | 1 |
| Sedlinsky, C | 1 |
| Mangano, A | 1 |
| Sen, L | 1 |
| Leiderman, S | 1 |
| Fernandez, G | 1 |
| Theas, S | 1 |
| Damilano, S | 1 |
| Gurfinkel, M | 1 |
| Seilicovich, A | 1 |
5 other studies available for pimagedine and Bone Loss, Osteoclastic
| Article | Year |
|---|---|
iNOS-derived nitric oxide stimulates osteoclast activity and alveolar bone loss in ligature-induced periodontitis in rats.
Topics: Alveolar Bone Loss; Animals; Bone Resorption; Cells, Cultured; Enzyme Inhibitors; Guanidines; In Vit | 2011 |
A possible role for nitric oxide in osteoclastogenesis associated with cholesteatoma.
Topics: Animals; Bone Resorption; Cells, Cultured; Cholesteatoma; Cytokines; Disease Models, Animal; Enzyme | 2004 |
Low NO concentrations inhibit osteoclast formation in mouse marrow cultures by cGMP-dependent mechanism.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bone Marrow Cells; Bone Resorption; Bucladesine; Ca | 1997 |
Decreased nitric oxide levels stimulate osteoclastogenesis and bone resorption both in vitro and in vivo on the chick chorioallantoic membrane in association with neoangiogenesis.
Topics: Acid Phosphatase; Allantois; Animals; Biomarkers; Bone and Bones; Bone Marrow Cells; Bone Resorption | 2000 |
Estrogenic status influences nitric oxide-regulated TNF-alpha release from human peripheral blood monocytes.
Topics: Adult; Animals; Bone and Bones; Bone Resorption; Calcium; Cells, Cultured; Enzyme Inhibitors; Estrog | 2001 |