pimagedine has been researched along with Blood Pressure, Low in 14 studies
pimagedine: diamine oxidase & nitric oxide synthase inhibitor; an advanced glycosylation end product inhibitor; used in the treatment of diabetic complications; structure
aminoguanidine : A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study compares the effects of aminoguanidine, a relatively selective inhibitor of inducible nitric oxide (NO) synthase, and N omega-nitro-L-arginine methyl ester (L-NAME), a selective inhibitor of endothelial NO synthase, on hypotension and multiple organ dysfunction caused by endotoxaemia in the anaesthetised rat." | 3.69 | Comparison of the effects of aminoguanidine and N omega-nitro-L-arginine methyl ester on the multiple organ dysfunction caused by endotoxaemia in the rat. ( Ruetten, H; Thiemermann, C; Wu, CC, 1996) |
| "Septic shock is characterized by arteriolar vasodilation and hypotension." | 1.31 | Inducible nitric oxide synthase pathway in the central nervous system and vasopressin release during experimental septic shock. ( Antunes-Rodrigues, J; Carnio, EC; De Castro, M; Giusti-Paiva, A, 2002) |
| "Furthermore, acidosis caused lung inflammation, as suggested by the increase in lung myeloperoxidase activity (282." | 1.30 | Acidosis stimulates nitric oxide production and lung damage in rats. ( Camporesi, EM; Caruso, JE; Hakim, TS; Hoffmann, SP; McGraw, DJ; Nandi, J; Oler, A; Pedoto, A; Tassiopoulos, AK, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (50.00) | 18.2507 |
| 2000's | 7 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Doursout, MF | 1 |
| Oguchi, T | 1 |
| Fischer, UM | 1 |
| Liang, Y | 1 |
| Chelly, B | 1 |
| Hartley, CJ | 1 |
| Chelly, JE | 1 |
| Lin, HC | 2 |
| Wan, FJ | 2 |
| Calvert, TJ | 1 |
| Chicoine, LG | 1 |
| Liu, Y | 1 |
| Nelin, LD | 1 |
| Zhang, W | 1 |
| Shibamoto, T | 1 |
| Cui, S | 1 |
| Takano, H | 1 |
| Kurata, Y | 1 |
| Lomis, TJ | 1 |
| Siffring, CW | 1 |
| Chalasani, S | 1 |
| Ziegler, DW | 1 |
| Lentz, KE | 1 |
| Stauffer, KE | 1 |
| McMillan, A | 1 |
| Agarwal, N | 1 |
| Lowenstein, CJ | 1 |
| Rhoads, JE | 1 |
| Klabunde, RE | 1 |
| Coston, AF | 1 |
| Wu, CC | 4 |
| Chen, SJ | 1 |
| Szabó, C | 1 |
| Thiemermann, C | 2 |
| Vane, JR | 1 |
| Ruetten, H | 1 |
| Yen, MH | 1 |
| Pedoto, A | 1 |
| Caruso, JE | 1 |
| Nandi, J | 1 |
| Oler, A | 1 |
| Hoffmann, SP | 1 |
| Tassiopoulos, AK | 1 |
| McGraw, DJ | 1 |
| Camporesi, EM | 1 |
| Hakim, TS | 1 |
| Kang, BH | 1 |
| Tseng, CJ | 1 |
| Chan, JY | 1 |
| Wang, SH | 1 |
| Chan, SH | 1 |
| Metcalf, K | 1 |
| Jungersten, L | 1 |
| Lisander, B | 1 |
| Giusti-Paiva, A | 1 |
| De Castro, M | 1 |
| Antunes-Rodrigues, J | 1 |
| Carnio, EC | 1 |
14 other studies available for pimagedine and Blood Pressure, Low
| Article | Year |
|---|---|
Distribution of NOS isoforms in a porcine endotoxin shock model.
Topics: Animals; Cardiomyopathies; Coronary Circulation; Disease Models, Animal; Enzyme Activation; Enzyme I | 2008 |
Hyperbaric oxygenation reduces overexpression of c-Fos and oxidative stress in the brain stem of experimental endotoxemic rats.
Topics: Analysis of Variance; Animals; Brain Stem; Guanidines; Hydralazine; Hyperbaric Oxygenation; Hypotens | 2008 |
Deficiency of mitogen-activated protein kinase phosphatase-1 results in iNOS-mediated hypotension in response to low-dose endotoxin.
Topics: Animals; Blood Pressure; Breath Tests; Disease Models, Animal; Dose-Response Relationship, Drug; Dua | 2008 |
7-nitroindazole, but not L-NAME or aminoguanidine, attenuates anaphylactic hypotension in conscious rats.
Topics: Anaphylaxis; Animals; Antigens; Enzyme Inhibitors; Guanidines; Hypotension; Indazoles; Male; NG-Nitr | 2009 |
First place winner of the Conrad Jobst Award in the gold medal paper competition. Nitric oxide synthase inhibitors N-monomethylarginine and aminoguanidine prevent the progressive and severe hypotension associated with a rat model of pancreatitis.
Topics: Amylases; Animals; Arginine; Blood Pressure; Calcium; Clinical Protocols; Disease Models, Animal; Dr | 1995 |
Nitric oxide synthase inhibition does not prevent cardiac depression in endotoxic shock.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cardiac Output, Low; Dexamethasone; Guanidines; Heart | 1995 |
Aminoguanidine attenuates the delayed circulatory failure and improves survival in rodent models of endotoxic shock.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Disease Models, Animal; Dose-Response | 1995 |
Comparison of the effects of aminoguanidine and N omega-nitro-L-arginine methyl ester on the multiple organ dysfunction caused by endotoxaemia in the rat.
Topics: Animals; Arginine; Blood Pressure; Dose-Response Relationship, Drug; Endotoxins; Enzyme Inhibitors; | 1996 |
Combined effects of dexamethasone and aminoguanidine on rats with endotoxemia.
Topics: Animals; Blood Pressure; Dexamethasone; Drug Interactions; Endotoxemia; Enzyme Inhibitors; Guanidine | 1998 |
Acidosis stimulates nitric oxide production and lung damage in rats.
Topics: Acidosis; Animals; Blood Gas Analysis; Blood Pressure; Disease Models, Animal; Dose-Response Relatio | 1999 |
Systemic administration of lipopolysaccharide induces release of nitric oxide and glutamate and c-fos expression in the nucleus tractus solitarii of rats.
Topics: Animals; Cardiovascular Physiological Phenomena; Chromatography, High Pressure Liquid; Data Interpre | 1999 |
Differential roles of iNOS and nNOS at rostral ventrolateral medulla during experimental endotoxemia in the rat.
Topics: Animals; Blood Pressure; Endotoxemia; Enzyme Inhibitors; Escherichia coli; Guanidines; Hypotension; | 2001 |
Effective inhibition of nitric oxide production by aminoguanidine does not reverse hypotension in endotoxaemic rats.
Topics: Animals; Blood Pressure; Dose-Response Relationship, Drug; Endotoxemia; Guanidines; Hypotension; Mal | 2002 |
Inducible nitric oxide synthase pathway in the central nervous system and vasopressin release during experimental septic shock.
Topics: Animals; Central Nervous System; Enzyme Inhibitors; Guanidines; Hemodynamics; Hypotension; Lipopolys | 2002 |