pimagedine has been researched along with Blood Poisoning in 21 studies
pimagedine: diamine oxidase & nitric oxide synthase inhibitor; an advanced glycosylation end product inhibitor; used in the treatment of diabetic complications; structure
aminoguanidine : A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sepsis is an arginine-deficient state and is associated with overproduction of nitric oxide (NO) by inducible nitric oxide synthase (iNOS)." | 7.74 | The effects of arginine and selective inducible nitric oxide synthase inhibitor on pathophysiology of sepsis in a CLP model. ( Akaishi, S; Endo, T; Hojo, N; Kobayashi, M; Kudo, D; Nomura, R; Sasaki, J; Shinozawa, Y; Takuma, K; Xie, XQ; Yamanouchi, S, 2008) |
| "Sepsis is an arginine-deficient state and is associated with overproduction of nitric oxide (NO) by inducible nitric oxide synthase (iNOS)." | 3.74 | The effects of arginine and selective inducible nitric oxide synthase inhibitor on pathophysiology of sepsis in a CLP model. ( Akaishi, S; Endo, T; Hojo, N; Kobayashi, M; Kudo, D; Nomura, R; Sasaki, J; Shinozawa, Y; Takuma, K; Xie, XQ; Yamanouchi, S, 2008) |
| "Sepsis was induced by cecal ligation and perforation in rats." | 1.32 | Septic diaphragmatic dysfunction is prevented by Mn(III)porphyrin therapy and inducible nitric oxide synthase inhibition. ( Alfonso, E; Batthyány, C; Boggia, J; Botti, H; Cassina, A; Hurtado, FJ; Nin, N; Peluffo, G; Radi, R; Rubbo, H; Trostchansky, A, 2004) |
| "Sepsis was induced by the intravenous administration of E." | 1.31 | Hemodynamic, biochemical and morphological changes induced by aminoguanidine in normal and septic sheep. ( Delgado, MA; Esteban, A; Fernández-Segoviano, P; Jara, N; Lorente, JA; Moscoso, A; Rodríguez-Corcos, A; Tejedor, C; Tobalina, R, 2000) |
| "Although sepsis is known to affect vascular function, little is known about changes at the capillary level." | 1.30 | Capillary and arteriolar responses to local vasodilators are impaired in a rat model of sepsis. ( McCormack, DG; Tyml, K; Yu, J, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.76) | 18.7374 |
| 1990's | 5 (23.81) | 18.2507 |
| 2000's | 10 (47.62) | 29.6817 |
| 2010's | 5 (23.81) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shafaroodi, H | 1 |
| Hassanipour, M | 1 |
| Mousavi, Z | 1 |
| Rahimi, N | 1 |
| Dehpour, AR | 1 |
| Bruhn, FH | 1 |
| Corrêa, PB | 2 |
| Oliveira-Pelegrin, GR | 2 |
| Rocha, MJ | 3 |
| Branco, LG | 1 |
| Ishikawa, K | 1 |
| Calzavacca, P | 1 |
| Bellomo, R | 1 |
| Bailey, M | 1 |
| May, CN | 1 |
| Seija, M | 1 |
| Baccino, C | 1 |
| Nin, N | 2 |
| Sánchez-Rodríguez, C | 1 |
| Granados, R | 1 |
| Ferruelo, A | 1 |
| Martínez-Caro, L | 1 |
| Ruíz-Cabello, J | 1 |
| de Paula, M | 1 |
| Noboa, O | 1 |
| Esteban, A | 2 |
| Lorente, JA | 2 |
| Anderson, RJ | 1 |
| Raykova, VD | 1 |
| Glibetic, M | 1 |
| Ofenstein, JP | 1 |
| Aranda, JV | 1 |
| HOFFMAN, DB | 1 |
| POLLACK, E | 1 |
| Puliti, M | 1 |
| von Hunolstein, C | 1 |
| Bistoni, F | 1 |
| Orefici, G | 1 |
| Tissi, L | 1 |
| Cassina, A | 1 |
| Boggia, J | 1 |
| Alfonso, E | 1 |
| Botti, H | 1 |
| Peluffo, G | 1 |
| Trostchansky, A | 1 |
| Batthyány, C | 1 |
| Radi, R | 1 |
| Rubbo, H | 1 |
| Hurtado, FJ | 1 |
| Pancoto, JA | 1 |
| de Oliveira-Pelegrin, GR | 1 |
| Cárnio, EC | 1 |
| Astolfi, RS | 1 |
| Khouri, DG | 1 |
| Brandizzi, LI | 1 |
| Avila-Campos, MJ | 1 |
| Andrade, HF | 1 |
| Xie, XQ | 1 |
| Shinozawa, Y | 1 |
| Sasaki, J | 1 |
| Takuma, K | 1 |
| Akaishi, S | 1 |
| Yamanouchi, S | 1 |
| Endo, T | 1 |
| Nomura, R | 1 |
| Kobayashi, M | 1 |
| Kudo, D | 1 |
| Hojo, N | 1 |
| Fretland, DJ | 1 |
| Anglin, C | 1 |
| Widomski, D | 1 |
| Connor, J | 1 |
| Wyatt, P | 1 |
| Manning, P | 1 |
| Currie, M | 1 |
| Tyml, K | 1 |
| Yu, J | 1 |
| McCormack, DG | 2 |
| Alden, KJ | 1 |
| Motew, SJ | 1 |
| Sharma, AC | 1 |
| Ferguson, JL | 1 |
| Tunçtan, B | 1 |
| Uludag, O | 1 |
| Altug, S | 1 |
| Abacioglu, N | 1 |
| Scott, JA | 1 |
| Wang, Y | 1 |
| Steinsland, OS | 1 |
| Nelson, SH | 1 |
| Benjamim, CF | 1 |
| Ferreira, SH | 1 |
| Cunha, FQ | 1 |
| Tejedor, C | 1 |
| Delgado, MA | 1 |
| Fernández-Segoviano, P | 1 |
| Jara, N | 1 |
| Tobalina, R | 1 |
| Rodríguez-Corcos, A | 1 |
| Moscoso, A | 1 |
21 other studies available for pimagedine and Blood Poisoning
| Article | Year |
|---|---|
The Effects of Sub-Chronic Treatment with Pioglitazone on the Septic Mice Mortality in the Model of Cecal Ligation and Puncture: Involvement of Nitric Oxide Pathway.
Topics: Animals; Cecum; Cytokines; Disease Models, Animal; Guanidines; Ligation; Male; Mice; Nitric Oxide; N | 2015 |
Blocking systemic nitric oxide production alters neuronal activation in brain structures involved in cardiovascular regulation during polymicrobial sepsis.
Topics: Animals; Area Postrema; Cardiovascular Physiological Phenomena; Guanidines; Locus Coeruleus; Male; M | 2009 |
Central NO-cGMP pathway in thermoregulation and survival rate during polymicrobial sepsis.
Topics: Animals; Body Temperature; Body Temperature Regulation; Cecum; Cyclic GMP; Guanidines; Injections, I | 2010 |
Effect of selective inhibition of renal inducible nitric oxide synthase on renal blood flow and function in experimental hyperdynamic sepsis.
Topics: Acute Kidney Injury; Animals; Disease Models, Animal; Female; Guanidines; Hemodynamics; Infusions, I | 2012 |
Role of peroxynitrite in sepsis-induced acute kidney injury in an experimental model of sepsis in rats.
Topics: Acute Kidney Injury; Acute-Phase Proteins; Animals; Aorta; Blood Flow Velocity; Blood Pressure; Dise | 2012 |
Acute kidney injury with sepsis: is nitric oxide a friend, foe, both, or neither?
Topics: Animals; Female; Guanidines; Nitric Oxide Synthase Type II; Renal Circulation; Sepsis | 2012 |
Nitric oxide-dependent regulation of pro-inflammatory cytokines in group B streptococcal inflammation of rat lung.
Topics: Animals; Arginine; Chemokine CXCL2; Chemokines, CXC; Gene Expression; Guanidines; Intercellular Sign | 2003 |
The protective effect of an antihistaminic on the toxemia-like changes caused by aminoguanidine sulfate in pregnant rats.
Topics: Amine Oxidase (Copper-Containing); Animals; Cyproheptadine; Female; Guanidines; Pre-Eclampsia; Pregn | 1963 |
Inhibition of nitric oxide synthase exacerbates group B streptococcus sepsis and arthritis in mice.
Topics: Animals; Animals, Outbred Strains; Arthritis, Infectious; Enzyme Inhibitors; Female; Guanidines; Hum | 2004 |
Septic diaphragmatic dysfunction is prevented by Mn(III)porphyrin therapy and inducible nitric oxide synthase inhibition.
Topics: Animals; Blood Pressure; Diaphragm; Enzyme Inhibitors; Guanidines; Heart Rate; Male; Metalloporphyri | 2004 |
Participation of iNOS-derived NO in hypothalamic activation and vasopressin release during polymicrobial sepsis.
Topics: Animals; Bacterial Infections; Blood Pressure; Drinking; Enzyme Inhibitors; Gene Expression Regulati | 2007 |
Antagonic effect of the inhibition of inducible nitric oxide on the mortality of mice acutely infected with Escherichia coli and Bacteroides fragilis.
Topics: Acute Disease; Animals; Bacteroides fragilis; Bacteroides Infections; Disease Models, Animal; Escher | 2007 |
The effects of arginine and selective inducible nitric oxide synthase inhibitor on pathophysiology of sepsis in a CLP model.
Topics: Animals; Arginine; Disease Models, Animal; Drug Therapy, Combination; Enzyme Inhibitors; Guanidines; | 2008 |
Temporal relationships of cytokine production in mouse non-lethal sepsis: effect of nitric oxide synthase inhibitors.
Topics: Animals; Cytokines; Enzyme Inhibitors; Guanidines; Interleukin-1; Interleukin-10; Kinetics; Lipopoly | 1997 |
Capillary and arteriolar responses to local vasodilators are impaired in a rat model of sepsis.
Topics: Acetylcholine; Animals; Arterioles; Body Weight; Capillaries; Enzyme Inhibitors; Guanidines; Iontoph | 1998 |
Effect of aminoguanidine on plasma nitric oxide by-products and blood flow during chronic peritoneal sepsis.
Topics: Animals; Blood Flow Velocity; Blood Pressure; Enzyme Inhibitors; Guanidines; Heart Rate; Hemodynamic | 1998 |
Effects of nitric oxide synthase inhibition in lipopolysaccharide-induced sepsis in mice.
Topics: Animals; Econazole; Enzyme Inhibitors; Female; Guanidines; Lipopolysaccharides; Male; Mice; Nitric O | 1998 |
Selective in vivo inhibition of inducible nitric oxide synthase in a rat model of sepsis.
Topics: Animals; Aorta, Thoracic; Blood Gas Analysis; Blood Pressure; Blood Vessels; Cecum; Enzyme Inhibitor | 1999 |
A role for nitric oxide in endotoxin-induced depletion of the peripheral catecholamine stores.
Topics: Adrenal Glands; Animals; Aorta; Arteries; Enzyme Inhibitors; Epinephrine; Female; Guanidines; Lipopo | 2000 |
Role of nitric oxide in the failure of neutrophil migration in sepsis.
Topics: Animals; Ascitic Fluid; Bacteremia; Cell Movement; Colony Count, Microbial; Cytokines; Disease Model | 2000 |
Hemodynamic, biochemical and morphological changes induced by aminoguanidine in normal and septic sheep.
Topics: Acidosis; Analysis of Variance; Animals; Blood Pressure; Case-Control Studies; Enzyme Inhibitors; Gu | 2000 |