Page last updated: 2024-10-22

pimagedine and Aortic Aneurysm, Abdominal

pimagedine has been researched along with Aortic Aneurysm, Abdominal in 3 studies

pimagedine: diamine oxidase & nitric oxide synthase inhibitor; an advanced glycosylation end product inhibitor; used in the treatment of diabetic complications; structure
aminoguanidine : A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.

Aortic Aneurysm, Abdominal: An abnormal balloon- or sac-like dilatation in the wall of the ABDOMINAL AORTA which gives rise to the visceral, the parietal, and the terminal (iliac) branches below the aortic hiatus at the diaphragm.

Research Excerpts

ExcerptRelevanceReference
"Background Although diabetes attenuates abdominal aortic aneurysms (AAAs), the mechanisms by which diabetes suppresses AAAs remain incompletely understood."1.91Treatment With Small Molecule Inhibitors of Advanced Glycation End-Products Formation and Advanced Glycation End-Products-Mediated Collagen Cross-Linking Promotes Experimental Aortic Aneurysm Progression in Diabetic Mice. ( Chen, X; Dalman, RL; Ge, Y; Guo, J; Ikezoe, T; Li, G; Li, Y; Miyata, M; Samura, M; Shoji, T; Xu, B; Zhao, S; Zheng, X, 2023)
"Both abdominal aortic aneurysms (AAAs) and inducible nitric oxide synthase (iNOS) are associated with inflammatory states, yet the relationship between NO production by iNOS and AAA development is unknown."1.31Inhibition of inducible nitric oxide synthase limits nitric oxide production and experimental aneurysm expansion. ( Carey, DJ; Elmore, JR; Franklin, DP; Han, DC; Johanning, JM, 2001)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's0 (0.00)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Li, Y1
Zheng, X1
Guo, J1
Samura, M1
Ge, Y1
Zhao, S1
Li, G1
Chen, X1
Shoji, T1
Ikezoe, T1
Miyata, M1
Xu, B1
Dalman, RL1
Johanning, JM2
Franklin, DP2
Han, DC2
Carey, DJ2
Elmore, JR2
Armstrong, PJ1

Other Studies

3 other studies available for pimagedine and Aortic Aneurysm, Abdominal

ArticleYear
Treatment With Small Molecule Inhibitors of Advanced Glycation End-Products Formation and Advanced Glycation End-Products-Mediated Collagen Cross-Linking Promotes Experimental Aortic Aneurysm Progression in Diabetic Mice.
    Journal of the American Heart Association, 2023, 05-16, Volume: 12, Issue:10

    Topics: Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Collagen; Diabetes Mellitus, Experimental; Di

2023
Inhibition of inducible nitric oxide synthase limits nitric oxide production and experimental aneurysm expansion.
    Journal of vascular surgery, 2001, Volume: 33, Issue:3

    Topics: Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Disease Models, Animal; Disease Progression;

2001
Nitric oxide in experimental aneurysm formation: early events and consequences of nitric oxide inhibition.
    Annals of vascular surgery, 2002, Volume: 16, Issue:1

    Topics: Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Blood Pressure; Enzyme Inhibitors; Guanidines

2002