pimagedine has been researched along with Anterior Choroidal Artery Infarction in 9 studies
pimagedine: diamine oxidase & nitric oxide synthase inhibitor; an advanced glycosylation end product inhibitor; used in the treatment of diabetic complications; structure
aminoguanidine : A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.
| Excerpt | Relevance | Reference |
|---|---|---|
| "During a cerebral infarction, a complex cascade of cytotoxic events ultimately determines the volume of brain cell loss." | 1.29 | Cerebroprotective effects of aminoguanidine in a rodent model of stroke. ( Bloom, O; Cerami, A; Cockroft, KM; Meistrell, M; Risucci, D; Tracey, KJ; Zimmerman, GA, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (66.67) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sun, M | 1 |
| Zhao, Y | 1 |
| Gu, Y | 1 |
| Xu, C | 1 |
| Zhu, DY | 1 |
| Deng, Q | 1 |
| Yao, HH | 1 |
| Wang, DC | 1 |
| Deng, Y | 1 |
| Liu, GQ | 1 |
| Park, EM | 1 |
| Cho, S | 1 |
| Frys, KA | 1 |
| Glickstein, SB | 1 |
| Zhou, P | 1 |
| Anrather, J | 1 |
| Ross, ME | 3 |
| Iadecola, C | 5 |
| Zhang, F | 4 |
| Xu, X | 1 |
| Zimmerman, GA | 2 |
| Meistrell, M | 2 |
| Bloom, O | 2 |
| Cockroft, KM | 2 |
| Bianchi, M | 1 |
| Risucci, D | 2 |
| Broome, J | 1 |
| Farmer, P | 1 |
| Cerami, A | 2 |
| Vlassara, H | 1 |
| Casey, RM | 1 |
| Casey, R | 1 |
| Clark, HB | 1 |
| Tracey, KJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase II Study of the Effects of Tiopronin on 3-Aminopropanal Level & Neurologic Outcome After Aneurysmal Subarachnoid Hemorrhage[NCT01095731] | Phase 2 | 60 participants (Actual) | Interventional | 2010-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
9 other studies available for pimagedine and Anterior Choroidal Artery Infarction
| Article | Year |
|---|---|
Neuroprotective actions of aminoguanidine involve reduced the activation of calpain and caspase-3 in a rat model of stroke.
Topics: Animals; Apoptosis; Biotransformation; Blotting, Western; Brain; Brain Edema; Calcium-Binding Protei | 2010 |
Inducible nitric oxide synthase expression in the ischemic core and penumbra after transient focal cerebral ischemia in mice.
Topics: Animals; Brain Ischemia; Cerebral Infarction; Disease Models, Animal; Enzyme Inhibitors; Guanidines; | 2002 |
Inducible nitric oxide synthase contributes to gender differences in ischemic brain injury.
Topics: Animals; Cerebral Infarction; Disease Models, Animal; Enzyme Inhibitors; Female; Gene Expression Reg | 2006 |
Inhibition of inducible nitric oxide synthase ameliorates cerebral ischemic damage.
Topics: Amino Acid Oxidoreductases; Analysis of Variance; Animals; Arginine; Blood Glucose; Blood Pressure; | 1995 |
Neurotoxicity of advanced glycation endproducts during focal stroke and neuroprotective effects of aminoguanidine.
Topics: Animals; Cerebral Infarction; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Glycati | 1995 |
Aminoguanidine ameliorates and L-arginine worsens brain damage from intraluminal middle cerebral artery occlusion.
Topics: Animals; Arginine; Arterial Occlusive Diseases; Base Sequence; Body Water; Brain; Brain Damage, Chro | 1996 |
Inducible nitric oxide synthase gene expression in vascular cells after transient focal cerebral ischemia.
Topics: Animals; Base Sequence; Cerebral Infarction; Cerebrovascular Circulation; Endothelium, Vascular; Enz | 1996 |
Cerebroprotective effects of aminoguanidine in a rodent model of stroke.
Topics: Animals; Cerebral Infarction; Cerebrovascular Circulation; Cerebrovascular Disorders; Disease Models | 1996 |
Temporal characteristics of the protective effect of aminoguanidine on cerebral ischemic damage.
Topics: Animals; Blood Glucose; Blood Pressure; Body Temperature; Brain Ischemia; Cerebral Infarction; Gases | 1998 |