pimagedine has been researched along with Alzheimer Disease in 10 studies
pimagedine: diamine oxidase & nitric oxide synthase inhibitor; an advanced glycosylation end product inhibitor; used in the treatment of diabetic complications; structure
aminoguanidine : A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.
Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 6 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Singh, M | 1 |
| Kaur, M | 1 |
| Singh, N | 1 |
| Silakari, O | 1 |
| Díaz, A | 1 |
| Rojas, K | 1 |
| Espinosa, B | 1 |
| Chávez, R | 1 |
| Zenteno, E | 1 |
| Limón, D | 1 |
| Guevara, J | 1 |
| Tóth, AE | 1 |
| Tóth, A | 1 |
| Walter, FR | 1 |
| Kiss, L | 1 |
| Veszelka, S | 1 |
| Ózsvári, B | 1 |
| Puskás, LG | 1 |
| Heimesaat, MM | 1 |
| Dohgu, S | 1 |
| Kataoka, Y | 1 |
| Rákhely, G | 1 |
| Deli, MA | 1 |
| Wei, Y | 1 |
| Han, C | 1 |
| Wang, Y | 1 |
| Wu, B | 1 |
| Su, T | 1 |
| Liu, Y | 1 |
| He, R | 1 |
| Liu, H | 1 |
| Chen, JP | 1 |
| Zhang, WQ | 1 |
| Carnevale, D | 1 |
| Mascio, G | 1 |
| D'Andrea, I | 1 |
| Fardella, V | 1 |
| Bell, RD | 1 |
| Branchi, I | 1 |
| Pallante, F | 1 |
| Zlokovic, B | 1 |
| Yan, SS | 1 |
| Lembo, G | 1 |
| Li, XH | 1 |
| Xie, JZ | 1 |
| Jiang, X | 1 |
| Lv, BL | 1 |
| Cheng, XS | 1 |
| Du, LL | 1 |
| Zhang, JY | 1 |
| Wang, JZ | 1 |
| Zhou, XW | 1 |
| Münch, G | 1 |
| Mayer, S | 1 |
| Michaelis, J | 1 |
| Hipkiss, AR | 1 |
| Riederer, P | 1 |
| Müller, R | 1 |
| Neumann, A | 1 |
| Schinzel, R | 1 |
| Cunningham, AM | 1 |
| Shapiro, HK | 1 |
| Stanyer, L | 1 |
| Betteridge, DJ | 1 |
| Smith, CC | 1 |
1 review available for pimagedine and Alzheimer Disease
| Article | Year |
|---|---|
Carbonyl-trapping therapeutic strategies.
Topics: Aldehydes; Alzheimer Disease; Amines; Animals; Carbohydrate Metabolism; Fatty Acids; Guanidines; Hum | 1998 |
9 other studies available for pimagedine and Alzheimer Disease
| Article | Year |
|---|---|
Exploration of multi-target potential of chromen-4-one based compounds in Alzheimer's disease: Design, synthesis and biological evaluations.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Cholinesterase Inhibitors; Chromans; Dose-Response | 2017 |
Aminoguanidine treatment ameliorates inflammatory responses and memory impairment induced by amyloid-beta 25-35 injection in rats.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Guanidines; Inflammation; Male; Memory Disorders; | 2014 |
Compounds blocking methylglyoxal-induced protein modification and brain endothelial injury.
Topics: Alzheimer Disease; Antioxidants; beta Catenin; Blood-Brain Barrier; Butadienes; Cell Line; Cell Surv | 2014 |
Ribosylation triggering Alzheimer's disease-like Tau hyperphosphorylation via activation of CaMKII.
Topics: Alzheimer Disease; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Survival; Diabe | 2015 |
[Inducible nitric oxide synthase induces beta-amyloid neurotoxicity in vivo].
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Guanidines; Indazoles; Male; Maze Learning; Nitri | 2002 |
Hypertension induces brain β-amyloid accumulation, cognitive impairment, and memory deterioration through activation of receptor for advanced glycation end products in brain vasculature.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Alzheimer Disease; Amyloid beta-Peptides; An | 2012 |
Methylglyoxal induces tau hyperphosphorylation via promoting AGEs formation.
Topics: Alzheimer Disease; Animals; Cell Line, Tumor; Enzyme Activation; Glycation End Products, Advanced; G | 2012 |
Influence of advanced glycation end-products and AGE-inhibitors on nucleation-dependent polymerization of beta-amyloid peptide.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Benzothiazoles; Carnosine; Cognition; Cross-Linking Reagen | 1997 |
An investigation into the mechanisms mediating plasma lipoprotein-potentiated beta-amyloid fibrillogenesis.
Topics: Aldehydes; Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Apolipoproteins; Ascorbic Acid; B | 2002 |