Page last updated: 2024-10-22

pimagedine and Allodynia

pimagedine has been researched along with Allodynia in 7 studies

pimagedine: diamine oxidase & nitric oxide synthase inhibitor; an advanced glycosylation end product inhibitor; used in the treatment of diabetic complications; structure
aminoguanidine : A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.

Research Excerpts

ExcerptRelevanceReference
" Optical densities of nitrotyrosine bands increased significantly in radiculopathy groups, but they were lowered by administration of aminoguanidine."3.79Inhibition of nitric oxide mediated protein nitration: therapeutic implications in experimental radiculopathy. ( Kim, TU; Lee, SJ; Park, JS; Ra, JY, 2013)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (28.57)18.2507
2000's3 (42.86)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hammoud, H1
Elhabazi, K1
Quillet, R1
Bertin, I1
Utard, V1
Laboureyras, E1
Bourguignon, JJ1
Bihel, F1
Simonnet, G1
Simonin, F1
Schmitt, M1
Lee, SJ1
Kim, TU1
Park, JS1
Ra, JY1
Shamshiri, H1
Paragomi, P1
Paydar, MJ1
Moezi, L1
Bahadori, M1
Behfar, B1
Ardalan, FA1
Dehpour, AR1
Dudhgaonkar, SP1
Tandan, SK1
Kumar, D1
Naik, AK1
Raviprakash, V1
Meller, ST1
Dykstra, C1
Grzybycki, D1
Murphy, S1
Gebhart, GF1
Osborne, MG1
Coderre, TJ1
Omote, K1
Hazama, K1
Kawamata, T1
Kawamata, M1
Nakayaka, Y1
Toriyabe, M1
Namiki, A1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Phase 2a Study of the Safety and Effectiveness of NXN-188 for the Acute Treatment of Migraine Attacks With Aura[NCT00877838]Phase 240 participants (Anticipated)Interventional2009-05-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

7 other studies available for pimagedine and Allodynia

ArticleYear
Aminoguanidine Hydrazone Derivatives as Nonpeptide NPFF1 Receptor Antagonists Reverse Opioid Induced Hyperalgesia.
    ACS chemical neuroscience, 2018, 11-21, Volume: 9, Issue:11

    Topics: Analgesics, Opioid; Animals; Drug Tolerance; Guanidines; Hydrazones; Hyperalgesia; Male; Mice; Nocic

2018
Inhibition of nitric oxide mediated protein nitration: therapeutic implications in experimental radiculopathy.
    Spine, 2013, Sep-15, Volume: 38, Issue:20

    Topics: Animals; Blotting, Western; Disease Models, Animal; Enzyme Inhibitors; Guanidines; Hindlimb; Hyperal

2013
Antinociceptive effect of chronic lithium on visceral hypersensitivity in a rat model of diarrhea-predominant irritable bowel syndrome: The role of nitric oxide pathway.
    Journal of gastroenterology and hepatology, 2009, Volume: 24, Issue:4

    Topics: Administration, Oral; Analgesics; Animals; Colon; Defecation; Diarrhea; Disease Models, Animal; Drug

2009
Ameliorative effect of combined administration of inducible nitric oxide synthase inhibitor with cyclooxygenase-2 inhibitors in neuropathic pain in rats.
    European journal of pain (London, England), 2007, Volume: 11, Issue:5

    Topics: Animals; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Drug

2007
The possible role of glia in nociceptive processing and hyperalgesia in the spinal cord of the rat.
    Neuropharmacology, 1994, Volume: 33, Issue:11

    Topics: Amino Acid Oxidoreductases; Animals; Behavior, Animal; Blotting, Southern; Citrates; Cytokines; Guan

1994
Effects of intrathecal administration of nitric oxide synthase inhibitors on carrageenan-induced thermal hyperalgesia.
    British journal of pharmacology, 1999, Volume: 126, Issue:8

    Topics: Animals; Carrageenan; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanidines; Hyperalgesia;

1999
Peripheral nitric oxide in carrageenan-induced inflammation.
    Brain research, 2001, Sep-07, Volume: 912, Issue:2

    Topics: Animals; Carrageenan; Drug Interactions; Edema; Enzyme Inhibitors; Guanidines; Hyperalgesia; Inflamm

2001