pimagedine has been researched along with Allodynia in 7 studies
pimagedine: diamine oxidase & nitric oxide synthase inhibitor; an advanced glycosylation end product inhibitor; used in the treatment of diabetic complications; structure
aminoguanidine : A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Optical densities of nitrotyrosine bands increased significantly in radiculopathy groups, but they were lowered by administration of aminoguanidine." | 3.79 | Inhibition of nitric oxide mediated protein nitration: therapeutic implications in experimental radiculopathy. ( Kim, TU; Lee, SJ; Park, JS; Ra, JY, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hammoud, H | 1 |
| Elhabazi, K | 1 |
| Quillet, R | 1 |
| Bertin, I | 1 |
| Utard, V | 1 |
| Laboureyras, E | 1 |
| Bourguignon, JJ | 1 |
| Bihel, F | 1 |
| Simonnet, G | 1 |
| Simonin, F | 1 |
| Schmitt, M | 1 |
| Lee, SJ | 1 |
| Kim, TU | 1 |
| Park, JS | 1 |
| Ra, JY | 1 |
| Shamshiri, H | 1 |
| Paragomi, P | 1 |
| Paydar, MJ | 1 |
| Moezi, L | 1 |
| Bahadori, M | 1 |
| Behfar, B | 1 |
| Ardalan, FA | 1 |
| Dehpour, AR | 1 |
| Dudhgaonkar, SP | 1 |
| Tandan, SK | 1 |
| Kumar, D | 1 |
| Naik, AK | 1 |
| Raviprakash, V | 1 |
| Meller, ST | 1 |
| Dykstra, C | 1 |
| Grzybycki, D | 1 |
| Murphy, S | 1 |
| Gebhart, GF | 1 |
| Osborne, MG | 1 |
| Coderre, TJ | 1 |
| Omote, K | 1 |
| Hazama, K | 1 |
| Kawamata, T | 1 |
| Kawamata, M | 1 |
| Nakayaka, Y | 1 |
| Toriyabe, M | 1 |
| Namiki, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase 2a Study of the Safety and Effectiveness of NXN-188 for the Acute Treatment of Migraine Attacks With Aura[NCT00877838] | Phase 2 | 40 participants (Anticipated) | Interventional | 2009-05-31 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 other studies available for pimagedine and Allodynia
| Article | Year |
|---|---|
Aminoguanidine Hydrazone Derivatives as Nonpeptide NPFF1 Receptor Antagonists Reverse Opioid Induced Hyperalgesia.
Topics: Analgesics, Opioid; Animals; Drug Tolerance; Guanidines; Hydrazones; Hyperalgesia; Male; Mice; Nocic | 2018 |
Inhibition of nitric oxide mediated protein nitration: therapeutic implications in experimental radiculopathy.
Topics: Animals; Blotting, Western; Disease Models, Animal; Enzyme Inhibitors; Guanidines; Hindlimb; Hyperal | 2013 |
Antinociceptive effect of chronic lithium on visceral hypersensitivity in a rat model of diarrhea-predominant irritable bowel syndrome: The role of nitric oxide pathway.
Topics: Administration, Oral; Analgesics; Animals; Colon; Defecation; Diarrhea; Disease Models, Animal; Drug | 2009 |
Ameliorative effect of combined administration of inducible nitric oxide synthase inhibitor with cyclooxygenase-2 inhibitors in neuropathic pain in rats.
Topics: Animals; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Drug | 2007 |
The possible role of glia in nociceptive processing and hyperalgesia in the spinal cord of the rat.
Topics: Amino Acid Oxidoreductases; Animals; Behavior, Animal; Blotting, Southern; Citrates; Cytokines; Guan | 1994 |
Effects of intrathecal administration of nitric oxide synthase inhibitors on carrageenan-induced thermal hyperalgesia.
Topics: Animals; Carrageenan; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanidines; Hyperalgesia; | 1999 |
Peripheral nitric oxide in carrageenan-induced inflammation.
Topics: Animals; Carrageenan; Drug Interactions; Edema; Enzyme Inhibitors; Guanidines; Hyperalgesia; Inflamm | 2001 |