pimagedine has been researched along with Allergic Encephalomyelitis in 10 studies
pimagedine: diamine oxidase & nitric oxide synthase inhibitor; an advanced glycosylation end product inhibitor; used in the treatment of diabetic complications; structure
aminoguanidine : A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In rodent models of MS, experimental autoimmune encephalomyelitis (EAE), it has been shown that nonspecific NOS inhibitors partially ameliorate the disease." | 1.30 | Experimental autoimmune encephalomyelitis is exacerbated in mice lacking the NOS2 gene. ( Brunnert, SR; Fenyk-Melody, JE; Garrison, AE; Mudgett, JS; Shelton, BA; Shen, F; Weidner, JR, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (60.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ljubisavljevic, S | 1 |
| Stojanovic, I | 1 |
| Pavlovic, D | 1 |
| Sokolovic, D | 1 |
| Stevanovic, I | 1 |
| Cross, AH | 2 |
| Misko, TP | 2 |
| Lin, RF | 1 |
| Hickey, WF | 2 |
| Trotter, JL | 1 |
| Tilton, RG | 2 |
| Zielasek, J | 1 |
| Jung, S | 1 |
| Gold, R | 1 |
| Liew, FY | 1 |
| Toyka, KV | 1 |
| Hartung, HP | 1 |
| Zhao, W | 1 |
| Corbett, JA | 1 |
| McDaniel, ML | 1 |
| Williamson, JR | 1 |
| Brenner, T | 1 |
| Brocke, S | 1 |
| Szafer, F | 1 |
| Sobel, RA | 1 |
| Parkinson, JF | 1 |
| Perez, DH | 1 |
| Steinman, L | 1 |
| Fenyk-Melody, JE | 1 |
| Garrison, AE | 1 |
| Brunnert, SR | 1 |
| Weidner, JR | 1 |
| Shen, F | 1 |
| Shelton, BA | 1 |
| Mudgett, JS | 1 |
| Okuda, Y | 1 |
| Sakoda, S | 1 |
| Fujimura, H | 1 |
| Yanagihara, T | 1 |
| Pozza, M | 1 |
| Bettelli, C | 1 |
| Aloe, L | 1 |
| Giardino, L | 1 |
| Calzà, L | 1 |
| Shin, T | 1 |
| Kim, S | 1 |
| Moon, C | 1 |
| Wie, M | 1 |
| Kim, H | 1 |
| Puerta, C | 1 |
| Martínez, I | 1 |
| Baranda, P | 1 |
| Blasco, MR | 1 |
| Castejón, R | 1 |
| Vargas, JA | 1 |
| García-Merino, A | 1 |
10 other studies available for pimagedine and Allergic Encephalomyelitis
| Article | Year |
|---|---|
Aminoguanidine and N-acetyl-cysteine supress oxidative and nitrosative stress in EAE rat brains.
Topics: Acetylcysteine; Animals; Brain; Encephalomyelitis, Autoimmune, Experimental; Female; Freund's Adjuva | 2011 |
Aminoguanidine, an inhibitor of inducible nitric oxide synthase, ameliorates experimental autoimmune encephalomyelitis in SJL mice.
Topics: Amino Acid Oxidoreductases; Animals; Encephalomyelitis, Autoimmune, Experimental; Female; Guanidines | 1994 |
Administration of nitric oxide synthase inhibitors in experimental autoimmune neuritis and experimental autoimmune encephalomyelitis.
Topics: Acetates; Amino Acid Oxidoreductases; Animals; Arginine; Encephalomyelitis, Autoimmune, Experimental | 1995 |
Experimental allergic encephalomyelitis in the rat is inhibited by aminoguanidine, an inhibitor of nitric oxide synthase.
Topics: Animals; Biomarkers; CD4-CD8 Ratio; Encephalomyelitis, Autoimmune, Experimental; Enzyme Inhibitors; | 1996 |
Inhibition of nitric oxide synthase for treatment of experimental autoimmune encephalomyelitis.
Topics: Animals; Astrocytes; Brain; Cells, Cultured; Chemokine CCL5; Cytokines; Encephalomyelitis, Autoimmun | 1997 |
Experimental autoimmune encephalomyelitis is exacerbated in mice lacking the NOS2 gene.
Topics: Amino Acid Sequence; Animals; Encephalomyelitis, Autoimmune, Experimental; Female; Guanidines; Mice; | 1998 |
Aminoguanidine, a selective inhibitor of the inducible nitric oxide synthase, has different effects on experimental allergic encephalomyelitis in the induction and progression phase.
Topics: Acute Disease; Animals; Autoimmune Diseases; Disease Progression; Drug Administration Schedule; Ence | 1998 |
Further evidence for a role of nitric oxide in experimental allergic encephalomyelitis: aminoguanidine treatment modifies its clinical evolution.
Topics: Acute Disease; Animals; Brain; Demyelinating Diseases; Disease Progression; Encephalomyelitis, Autoi | 2000 |
Aminoguanidine-induced amelioration of autoimmune encephalomyelitis is mediated by reduced expression of inducible nitric oxide synthase in the spinal cord.
Topics: Animals; Encephalomyelitis, Autoimmune, Experimental; Enzyme Inhibitors; Female; Guanidines; Male; N | 2000 |
Aminoguanidine reduces apoptosis of circulating V Beta 8.2 T lymphocytes in Lewis rats with actively induced experimental autoimmune encephalomyelitis. Association with persistent inflammation of the central nervous system and lack of recovery.
Topics: Animals; Apoptosis; Cell Division; Encephalomyelitis, Autoimmune, Experimental; Enzyme Inhibitors; G | 2000 |