pimagedine has been researched along with Adjuvant Arthritis in 12 studies
pimagedine: diamine oxidase & nitric oxide synthase inhibitor; an advanced glycosylation end product inhibitor; used in the treatment of diabetic complications; structure
aminoguanidine : A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Progression of the chronic synovitis in zymosan-induced arthritis (ZYA) was associated with increased nitrite and nitrotyrosine (3-NT) levels in the joint exudates that paralleled a progressive loss of the GAG content." | 3.72 | Reactive nitrogen species scavenging, rather than nitric oxide inhibition, protects from articular cartilage damage in rat zymosan-induced arthritis. ( Bezerra, MM; Brain, SD; da Rocha, FA; de Melo, LB; Greenacre, S; Jerônimo, SM; Keeble, J, 2004) |
| "Inflammation was assessed by measurement of NO and prostaglandin E2 (PGE2) levels and the lysosomal leakage of the enzyme N-acetyl-B-D-glucosaminidase (NAG) into the exudate of the granuloma pouch 4 h after carrageenan injection." | 1.31 | Modulation of nitric oxide synthesis in inflammation. Relationship to oxygen-derived free radicals and prostaglandin synthesis. ( Gad, MZ; Khattab, M, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (25.00) | 18.2507 |
| 2000's | 7 (58.33) | 29.6817 |
| 2010's | 2 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tinker, AC | 1 |
| Beaton, HG | 1 |
| Boughton-Smith, N | 1 |
| Cook, TR | 1 |
| Cooper, SL | 1 |
| Fraser-Rae, L | 1 |
| Hallam, K | 1 |
| Hamley, P | 1 |
| McInally, T | 1 |
| Nicholls, DJ | 1 |
| Pimm, AD | 1 |
| Wallace, AV | 1 |
| Franchin, M | 1 |
| Colón, DF | 1 |
| da Cunha, MG | 1 |
| Castanheira, FV | 1 |
| Saraiva, AL | 1 |
| Bueno-Silva, B | 1 |
| Alencar, SM | 1 |
| Cunha, TM | 1 |
| Rosalen, PL | 1 |
| Kato, S | 1 |
| Kawahara, R | 1 |
| Yasuda, M | 1 |
| Amagase, K | 1 |
| Takeuchi, K | 1 |
| Nagai, N | 1 |
| Takeda, A | 1 |
| Itanami, Y | 1 |
| Ito, Y | 1 |
| Ibáñez de Cáceres, I | 2 |
| Priego, T | 2 |
| Martín, AI | 2 |
| López-Calderón, A | 2 |
| Villanúa, MA | 2 |
| Granado, M | 1 |
| Bezerra, MM | 1 |
| Brain, SD | 1 |
| Greenacre, S | 1 |
| Jerônimo, SM | 1 |
| de Melo, LB | 1 |
| Keeble, J | 1 |
| da Rocha, FA | 2 |
| Connor, JR | 1 |
| Manning, PT | 1 |
| Settle, SL | 1 |
| Moore, WM | 1 |
| Jerome, GM | 1 |
| Webber, RK | 1 |
| Tjoeng, FS | 1 |
| Currie, MG | 1 |
| Stefanovic-Racic, M | 1 |
| Meyers, K | 1 |
| Meschter, C | 1 |
| Coffey, JW | 1 |
| Hoffman, RA | 1 |
| Evans, CH | 1 |
| Pozza, M | 1 |
| Bettelli, C | 1 |
| Magnani, F | 1 |
| Mascia, MT | 1 |
| Manzini, E | 1 |
| Calzà, L | 1 |
| Gad, MZ | 1 |
| Khattab, M | 1 |
| da S Rocha, JC | 1 |
| Peixoto, ME | 1 |
| Jancar, S | 1 |
| de Q Cunha, F | 1 |
| de A Ribeiro, R | 1 |
12 other studies available for pimagedine and Adjuvant Arthritis
| Article | Year |
|---|---|
1,2-Dihydro-4-quinazolinamines: potent, highly selective inhibitors of inducible nitric oxide synthase which show antiinflammatory activity in vivo.
Topics: Acute Disease; Administration, Oral; Amines; Animals; Arthritis, Experimental; Cell Line; Chronic Di | 2003 |
Neovestitol, an isoflavonoid isolated from Brazilian red propolis, reduces acute and chronic inflammation: involvement of nitric oxide and IL-6.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Brazil; CD4-Positive T-Ly | 2016 |
Aggravation of cold-restraint stress-induced gastric lesions in adjuvant arthritic rats: pathogenic role of inducible and endothelial nitric oxide.
Topics: Animals; Arthritis, Experimental; Blotting, Western; Cold Temperature; Enzyme Inhibitors; Gastric Mu | 2009 |
Co-administration of water containing magnesium ion prevents loxoprofen-induced lesions in gastric mucosa of adjuvant-induced arthritis rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arthritis, Experimental; Drug T | 2012 |
The inhibition of inducible nitric oxide synthase reverts arthritic-induced decrease in pituitary growth hormone mRNA but not in liver insulin-like growth factor I mRNA expression.
Topics: Animals; Arthritis, Experimental; Chronic Disease; Enzyme Inhibitors; Gene Expression; Growth Hormon | 2003 |
Effect of inducible nitric oxide synthase inhibition by aminoguanidine on insulin-like growth factor binding protein-3 in adjuvant-induced arthritic rats.
Topics: Animals; Arthritis, Experimental; Enzyme Inhibitors; Guanidines; Insulin-Like Growth Factor Binding | 2003 |
Reactive nitrogen species scavenging, rather than nitric oxide inhibition, protects from articular cartilage damage in rat zymosan-induced arthritis.
Topics: Animals; Arthritis, Experimental; Cartilage, Articular; Disease Models, Animal; Dose-Response Relati | 2004 |
Suppression of adjuvant-induced arthritis by selective inhibition of inducible nitric oxide synthase.
Topics: Amino Acid Oxidoreductases; Amino Acid Sequence; Animals; Arthritis, Experimental; Blood Pressure; E | 1995 |
Comparison of the nitric oxide synthase inhibitors methylarginine and aminoguanidine as prophylactic and therapeutic agents in rat adjuvant arthritis.
Topics: Animals; Arthritis, Experimental; Cartilage, Articular; Cells, Cultured; Dose-Response Relationship, | 1995 |
Is neuronal nitric oxide involved in adjuvant-induced joint inflammation?
Topics: Animals; Arthritis, Experimental; Enzyme Inhibitors; Ganglia, Spinal; Guanidines; Male; Neurons; Nit | 1998 |
Modulation of nitric oxide synthesis in inflammation. Relationship to oxygen-derived free radicals and prostaglandin synthesis.
Topics: Acetylglucosaminidase; Animals; Arthritis, Experimental; Carrageenan; Dinoprostone; Enzyme Inhibitor | 2000 |
Dual effect of nitric oxide in articular inflammatory pain in zymosan-induced arthritis in rats.
Topics: Amidines; Animals; Arthritis, Experimental; Benzylamines; Cartilage, Articular; Dinoprost; Edema; En | 2002 |