pimagedine has been researched along with Acute Liver Injury, Drug-Induced in 10 studies
pimagedine: diamine oxidase & nitric oxide synthase inhibitor; an advanced glycosylation end product inhibitor; used in the treatment of diabetic complications; structure
aminoguanidine : A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Azathioprine (AZA) is an important drug used in the therapy of autoimmune system disorders." | 1.32 | A comparison of hepatoprotective activities of aminoguanidine and N-acetylcysteine in rat against the toxic damage induced by azathioprine. ( Ahmad, M; Al-Shabanah, OA; Gado, A; Raza, M, 2003) |
| "The aim of this work was to determine if the inhibition or stimulation of NO synthesis modulates liver damage induced by the chronic administration of CCl4." | 1.30 | Nitric oxide protection of rat liver from lipid peroxidation, collagen accumulation, and liver damage induced by carbon tetrachloride. ( Muriel, P, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 5 (50.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fourches, D | 1 |
| Barnes, JC | 1 |
| Day, NC | 1 |
| Bradley, P | 1 |
| Reed, JZ | 1 |
| Tropsha, A | 1 |
| Saad, EI | 1 |
| El-Gowilly, SM | 1 |
| Sherhaa, MO | 1 |
| Bistawroos, AE | 1 |
| Gardner, CR | 1 |
| Laskin, JD | 1 |
| Dambach, DM | 1 |
| Sacco, M | 1 |
| Durham, SK | 1 |
| Bruno, MK | 1 |
| Cohen, SD | 1 |
| Gordon, MK | 1 |
| Gerecke, DR | 1 |
| Zhou, P | 1 |
| Laskin, DL | 1 |
| Raza, M | 1 |
| Ahmad, M | 1 |
| Gado, A | 1 |
| Al-Shabanah, OA | 1 |
| Rose, R | 1 |
| Banerjee, A | 1 |
| Ramaiah, SK | 1 |
| Abdel-Zaher, AO | 1 |
| Abdel-Rahman, MM | 1 |
| Hafez, MM | 1 |
| Omran, FM | 1 |
| Aoki, K | 1 |
| Ohmori, M | 1 |
| Takimoto, M | 1 |
| Ota, H | 1 |
| Yoshida, T | 1 |
| Muriel, P | 1 |
| Tanaka, N | 1 |
| Tanaka, K | 1 |
| Nagashima, Y | 1 |
| Kondo, M | 1 |
| Sekihara, H | 1 |
| Okamoto, T | 1 |
| Okabe, S | 1 |
10 other studies available for pimagedine and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLI | 2010 |
Role of oxidative stress and nitric oxide in the protective effects of alpha-lipoic acid and aminoguanidine against isoniazid-rifampicin-induced hepatotoxicity in rats.
Topics: Animals; Antioxidants; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Glutathione; G | 2010 |
Reduced hepatotoxicity of acetaminophen in mice lacking inducible nitric oxide synthase: potential role of tumor necrosis factor-alpha and interleukin-10.
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Connective Tissue Growth Factor; Gen | 2002 |
A comparison of hepatoprotective activities of aminoguanidine and N-acetylcysteine in rat against the toxic damage induced by azathioprine.
Topics: Acetylcysteine; Animals; Azathioprine; Chemical and Drug Induced Liver Injury; Drug Therapy, Combina | 2003 |
Calpain inhibition attenuates iNOS production and midzonal hepatic necrosis in a repeat dose model of endotoxemia in rats.
Topics: Animals; Anticoagulants; Blood Coagulation; Blotting, Western; Calpain; Carrier Proteins; Chemical a | 2006 |
Role of nitric oxide and reduced glutathione in the protective effects of aminoguanidine, gadolinium chloride and oleanolic acid against acetaminophen-induced hepatic and renal damage.
Topics: Acetaminophen; Administration, Oral; Alanine Transaminase; Alkaline Phosphatase; Analgesics, Non-Nar | 2007 |
Cocaine-induced liver injury in mice is mediated by nitric oxide and reactive oxygen species.
Topics: Allopurinol; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Cocaine; Enzyme Inhibito | 1997 |
Nitric oxide protection of rat liver from lipid peroxidation, collagen accumulation, and liver damage induced by carbon tetrachloride.
Topics: Animals; Arginine; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Collagen; Drug Inte | 1998 |
Nitric oxide increases hepatic arterial blood flow in rats with carbon tetrachloride-induced acute hepatic injury.
Topics: Acute Disease; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Enzyme Inhibit | 1999 |
Inhibition of anti-Fas antibody-induced hepatitis by aminoguanidine in mice.
Topics: Animals; Antibodies; Aspartate Aminotransferases; Caspases; Chemical and Drug Induced Liver Injury; | 2000 |