pilsicainide has been researched along with Ventricular Fibrillation in 27 studies
pilsicainide: structure given in first source
pilsicainide : A secondary carboxamide resulting from the formal condensation of the amino group of 2,6-dimethylaniline with the carboxy group of (tetrahydro-1H-pyrrolizin-7a(5H)-yl)acetic acid. It is a sodium channel blocker which is used as an antiarrhythmic drug for the management of atrial tachyarrhythmias in Japan.
Ventricular Fibrillation: A potentially lethal cardiac arrhythmia that is characterized by uncoordinated extremely rapid firing of electrical impulses (400-600/min) in HEART VENTRICLES. Such asynchronous ventricular quivering or fibrillation prevents any effective cardiac output and results in unconsciousness (SYNCOPE). It is one of the major electrocardiographic patterns seen with CARDIAC ARREST.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We performed a pilsicainide challenge test in a 38-year-old man who was resuscitated from ventricular fibrillation without apparent baseline electrocardiogram (ECG) abnormality." | 7.73 | Spontaneous polymorphic ventricular tachycardia after administration of pilsicainide in a patient resuscitated from ventricular fibrillation. ( Araki, S; Ogawa, H; Sadanaga, T; Tanaka, Y, 2006) |
| "A 56-year-old man with Brugada syndrome presented with ventricular fibrillation induced by administration of pilsicainide." | 7.72 | [Brugada syndrome associated with ventricular fibrillation induced by administration of pilsicainide: a case report]. ( Ebina, T; Ishikawa, T; Kimura, K; Kobayashi, T; Matsumoto, K; Matsushita, K; Mochida, Y; Nakagawa, T; Nakazawa, I; Ohkusu, Y; Sumita, S; Uchino, K; Umemura, S; Yamakawa, Y, 2003) |
| " We investigated the association between spontaneous ventricular fibrillation (VF) occurrence and TWA after pilsicainide, a sodium channel blocker administration in BS patients." | 5.13 | Clinical significance of macroscopic T-wave alternans after sodium channel blocker administration in patients with Brugada syndrome. ( Banba, K; Kusano, KF; Miura, D; Morita, H; Nagase, S; Nakamura, K; Nishii, N; Ohe, T; Tada, T; Watanabe, A, 2008) |
| "We administered intravenous pilsicainide to 245 consecutive patients with Brugada syndrome (181 patients with spontaneous type 1 ECG, 64 patients with non-type 1 ECG)." | 3.88 | Prognostic Significance of the Sodium Channel Blocker Test in Patients With Brugada Syndrome. ( Ito, H; Kawada, S; Miyamoto, M; Morimoto, Y; Morita, H; Nakagawa, K; Nishii, N; Tachibana, M; Ueoka, A; Watanabe, A, 2018) |
| "We performed a pilsicainide challenge test in a 38-year-old man who was resuscitated from ventricular fibrillation without apparent baseline electrocardiogram (ECG) abnormality." | 3.73 | Spontaneous polymorphic ventricular tachycardia after administration of pilsicainide in a patient resuscitated from ventricular fibrillation. ( Araki, S; Ogawa, H; Sadanaga, T; Tanaka, Y, 2006) |
| "A 56-year-old man with Brugada syndrome presented with ventricular fibrillation induced by administration of pilsicainide." | 3.72 | [Brugada syndrome associated with ventricular fibrillation induced by administration of pilsicainide: a case report]. ( Ebina, T; Ishikawa, T; Kimura, K; Kobayashi, T; Matsumoto, K; Matsushita, K; Mochida, Y; Nakagawa, T; Nakazawa, I; Ohkusu, Y; Sumita, S; Uchino, K; Umemura, S; Yamakawa, Y, 2003) |
| "Amiodarone (200 mg/day) was administered for 6 months and programmed ventricular stimulation was repeated." | 1.32 | Intravenous administration of class I antiarrhythmic drug induced T wave alternans in an asymptomatic Brugada syndrome patient. ( Kanmatsuse, K; Kasamaki, Y; Kofune, T; Masaki, R; Ohkubo, K; Okumura, Y; Oshikawa, N; Ozawa, Y; Saito, S; Watanabe, I; Yamada, T, 2003) |
| "Ventricular fibrillation was induced with double extrastimuli applied to the right ventricular outflow tract." | 1.31 | [Brugada syndrome occurring in an identical twin: a case report]. ( Fujiki, A; Inoue, H; Mizumaki, K; Nishida, K; Sakabe, M; Sugao, M; Tsuneda, T, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (3.70) | 18.2507 |
| 2000's | 17 (62.96) | 29.6817 |
| 2010's | 7 (25.93) | 24.3611 |
| 2020's | 2 (7.41) | 2.80 |
| Authors | Studies |
|---|---|
| Hasebe, H | 1 |
| Yokoya, T | 1 |
| Murakoshi, N | 1 |
| Kurebayashi, N | 1 |
| Taki, M | 1 |
| Muraji, S | 1 |
| Mori, H | 1 |
| Nabeshima, T | 1 |
| Toda, K | 1 |
| Iwamoto, Y | 1 |
| Masutani, S | 1 |
| Kojima, T | 1 |
| Yoshiba, S | 1 |
| Kobayashi, T | 2 |
| Sumitomo, N | 1 |
| Kakihara, J | 1 |
| Takagi, M | 2 |
| Hayashi, Y | 1 |
| Tatsumi, H | 1 |
| Doi, A | 2 |
| Yoshiyama, M | 1 |
| Ueoka, A | 1 |
| Morita, H | 4 |
| Watanabe, A | 2 |
| Morimoto, Y | 1 |
| Kawada, S | 1 |
| Tachibana, M | 1 |
| Miyamoto, M | 1 |
| Nakagawa, K | 1 |
| Nishii, N | 2 |
| Ito, H | 1 |
| Nagayama, T | 1 |
| Nagase, S | 4 |
| Kamakura, T | 2 |
| Wada, M | 2 |
| Ishibashi, K | 2 |
| Inoue, YY | 1 |
| Miyamoto, K | 2 |
| Noda, T | 3 |
| Aiba, T | 4 |
| Takaki, H | 2 |
| Sugimachi, M | 2 |
| Shimizu, W | 4 |
| Noguchi, T | 1 |
| Yasuda, S | 2 |
| Kamakura, S | 3 |
| Kusano, K | 2 |
| Yagishita, A | 1 |
| Yamauchi, Y | 2 |
| Obayashi, T | 1 |
| Hirao, K | 1 |
| Nakajima, I | 1 |
| Okamura, H | 1 |
| Ogawa, H | 2 |
| Makiyama, T | 1 |
| Kimura, T | 1 |
| Kofune, M | 1 |
| Watanabe, I | 2 |
| Ashino, S | 1 |
| Ohkubo, K | 2 |
| Okumura, Y | 2 |
| Kofune, T | 2 |
| Nakai, T | 1 |
| Hirayama, A | 1 |
| Sugi, N | 1 |
| Shimizu, A | 1 |
| Ueyama, T | 1 |
| Yoshiga, Y | 1 |
| Doi, M | 1 |
| Ohmiya, T | 1 |
| Ohno, M | 1 |
| Yoshida, M | 1 |
| Matsuzaki, M | 1 |
| Hisada, T | 1 |
| Miyagawa, T | 1 |
| Yakushiji, T | 1 |
| Tsujimoto, T | 1 |
| Sakai, M | 1 |
| Adachi, T | 1 |
| Ikewaki, K | 1 |
| Ogata, K | 1 |
| Ohsuzu, F | 1 |
| Sakurai, Y | 1 |
| Takeuchi, K | 1 |
| Yoshikawa, J | 1 |
| Sakabe, M | 1 |
| Fujiki, A | 1 |
| Tsuneda, T | 1 |
| Nishida, K | 1 |
| Sugao, M | 1 |
| Mizumaki, K | 1 |
| Inoue, H | 1 |
| Takenaka-Morita, S | 1 |
| Fukushima-Kusano, K | 1 |
| Kobayashi, M | 1 |
| Kakishita, M | 1 |
| Nakamura, K | 4 |
| Emori, T | 2 |
| Matsubara, H | 2 |
| Ohe, T | 3 |
| Nogami, A | 1 |
| Nakao, M | 1 |
| Kubota, S | 1 |
| Sugiyasu, A | 1 |
| Doi, H | 1 |
| Yokoyama, K | 1 |
| Yumoto, K | 1 |
| Tamaki, T | 1 |
| Kato, K | 1 |
| Hosokawa, N | 1 |
| Sagai, H | 1 |
| Nakamura, H | 1 |
| Nitta, J | 1 |
| Aonuma, K | 1 |
| Yamada, T | 1 |
| Masaki, R | 1 |
| Oshikawa, N | 1 |
| Kasamaki, Y | 1 |
| Saito, S | 1 |
| Ozawa, Y | 1 |
| Kanmatsuse, K | 1 |
| Matsumoto, K | 1 |
| Sumita, S | 1 |
| Ishikawa, T | 1 |
| Matsushita, K | 1 |
| Ohkusu, Y | 1 |
| Yamakawa, Y | 1 |
| Nakagawa, T | 1 |
| Nakazawa, I | 1 |
| Mochida, Y | 1 |
| Ebina, T | 1 |
| Uchino, K | 1 |
| Kimura, K | 1 |
| Umemura, S | 1 |
| Arai, M | 1 |
| Nakazawa, K | 1 |
| Takagi, A | 1 |
| Kishi, R | 1 |
| Osada, K | 1 |
| Ryu, S | 1 |
| Miyake, F | 1 |
| Hidaka, I | 1 |
| Uemura, K | 1 |
| Zheng, C | 1 |
| Kamiya, A | 1 |
| Inagaki, M | 1 |
| Sunagawa, K | 1 |
| Ikeda, T | 1 |
| Abe, A | 1 |
| Yusu, S | 1 |
| Ishiguro, H | 1 |
| Mera, H | 1 |
| Yotsukura, M | 1 |
| Yoshino, H | 1 |
| Sadanaga, T | 1 |
| Araki, S | 1 |
| Tanaka, Y | 1 |
| Chinushi, M | 1 |
| Izumi, D | 1 |
| Furushima, H | 1 |
| Watanabe, H | 2 |
| Aizawa, Y | 1 |
| Tada, T | 1 |
| Kusano, KF | 2 |
| Banba, K | 1 |
| Miura, D | 1 |
| Madias, JE | 1 |
| Nakazato, Y | 1 |
| Nakata, Y | 1 |
| Yasuda, M | 1 |
| Yamagami, S | 1 |
| Tokano, T | 1 |
| Nakazato, K | 1 |
| Sumiyoshi, M | 1 |
| Ogura, S | 1 |
| Yamaguchi, H | 1 |
| Takenaka, S | 1 |
| Hisamatsu, K | 1 |
| Kurita, T | 1 |
| Sahara, M | 1 |
| Sagara, K | 1 |
| Yamashita, T | 1 |
| Abe, T | 1 |
| Kirigaya, H | 1 |
| Nakada, M | 1 |
| Iinuma, H | 1 |
| Fu, LT | 1 |
1 trial available for pilsicainide and Ventricular Fibrillation
| Article | Year |
|---|---|
Clinical significance of macroscopic T-wave alternans after sodium channel blocker administration in patients with Brugada syndrome.
Topics: Brugada Syndrome; Electrocardiography; Female; Humans; Lidocaine; Male; Middle Aged; Sodium Channel | 2008 |
26 other studies available for pilsicainide and Ventricular Fibrillation
| Article | Year |
|---|---|
Pilsicainide Administration Unmasks a Phenotype of Brugada Syndrome in a Patient with Overlap Syndrome due to the E1784K SCN5A Mutation.
Topics: Adult; Anti-Arrhythmia Agents; Brugada Syndrome; Electrocardiography; Humans; Lidocaine; Long QT Syn | 2020 |
Efficacy of a Subcutaneous Implantable Cardioverter Defibrillator in a Child with Early Repolarization Syndrome.
Topics: Anti-Arrhythmia Agents; Child; Death, Sudden, Cardiac; Defibrillators, Implantable; Electrocardiogra | 2021 |
Utility of 12-lead and signal-averaged Holter electrocardiograms after pilsicainide provocation for risk stratification in Brugada syndrome.
Topics: Anti-Arrhythmia Agents; Brugada Syndrome; Electrocardiography, Ambulatory; Female; Humans; Lidocaine | 2017 |
Prognostic Significance of the Sodium Channel Blocker Test in Patients With Brugada Syndrome.
Topics: Administration, Intravenous; Adult; Aged; Brugada Syndrome; Death, Sudden, Cardiac; Electrocardiogra | 2018 |
Clinical and Electrocardiographic Differences in Brugada Syndrome With Spontaneous or Drug-Induced Type 1 Electrocardiogram.
Topics: Adult; Anti-Arrhythmia Agents; Brugada Syndrome; Electrocardiography; Female; Humans; Lidocaine; Mal | 2019 |
Idiopathic ventricular fibrillation associated with early repolarization which was unmasked by a sodium channel blocker after catheter ablation of atrial fibrillation.
Topics: Atrial Fibrillation; Catheter Ablation; Electrocardiography; Female; Follow-Up Studies; Humans; Inje | 2014 |
Significance of electrocardiogram recording in high intercostal spaces in patients with early repolarization syndrome.
Topics: Adult; Anti-Arrhythmia Agents; Brugada Syndrome; Electrocardiography; Electrophysiologic Techniques, | 2016 |
Action potential alternans in the right ventricular outflow tract in a patient with asymptomatic Brugada syndrome.
Topics: Action Potentials; Aged; Anti-Arrhythmia Agents; Brugada Syndrome; Electrocardiography; Humans; Lido | 2009 |
What variables were associated with the inducibility of ventricular fibrillation during electrophysiologic stimulation test in patients without apparent organic heart disease?
Topics: Brugada Syndrome; Electric Stimulation; Electrocardiography; Female; Humans; Lidocaine; Male; Middle | 2010 |
Ventricular fibrillation diagnosed during electrophysiological study for non-sustained tachycardia.
Topics: Adult; Anti-Arrhythmia Agents; Brugada Syndrome; Electrocardiography; Humans; Japan; Lidocaine; Male | 2010 |
Pilsicanide-induced marked T wave alternans and ventricular fibrillation in a patient with Brugada syndrome.
Topics: Adult; Anti-Arrhythmia Agents; Bundle-Branch Block; Electrocardiography; Humans; Lidocaine; Long QT | 2002 |
[Brugada syndrome occurring in an identical twin: a case report].
Topics: Anti-Arrhythmia Agents; Bundle-Branch Block; Diseases in Twins; Electrocardiography; Humans; Lidocai | 2002 |
Risk stratification for asymptomatic patients with Brugada syndrome.
Topics: Adult; Aged; Anti-Arrhythmia Agents; Bundle-Branch Block; Cardiac Pacing, Artificial; Electrocardiog | 2003 |
Enhancement of J-ST-segment elevation by the glucose and insulin test in Brugada syndrome.
Topics: Adult; Anti-Arrhythmia Agents; Bundle-Branch Block; Electrocardiography; Glucose; Heart Arrest; Huma | 2003 |
Intravenous administration of class I antiarrhythmic drug induced T wave alternans in an asymptomatic Brugada syndrome patient.
Topics: Amiodarone; Anti-Arrhythmia Agents; Bundle-Branch Block; Cardiac Pacing, Artificial; Electrocardiogr | 2003 |
[Brugada syndrome associated with ventricular fibrillation induced by administration of pilsicainide: a case report].
Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Electrocardiography; Electrophysiology; Humans; Lidocai | 2003 |
Brugada syndrome-like ST-segment elevation increase exacerbated by vomiting.
Topics: Acetylcholine; Anti-Arrhythmia Agents; Coronary Vessels; Electrocardiography; Humans; Infusions, Int | 2004 |
Cellular basis for trigger and maintenance of ventricular fibrillation in the Brugada syndrome model: high-resolution optical mapping study.
Topics: Action Potentials; Animals; Cardiovascular Agents; Disease Models, Animal; Dogs; Electrocardiography | 2006 |
The full stomach test as a novel diagnostic technique for identifying patients at risk of Brugada syndrome.
Topics: Adult; Brugada Syndrome; Circadian Rhythm; Electrocardiography; Electrophysiologic Techniques, Cardi | 2006 |
Spontaneous polymorphic ventricular tachycardia after administration of pilsicainide in a patient resuscitated from ventricular fibrillation.
Topics: Adult; Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Electric Countershock; Humans; Lidocai | 2006 |
Multiple premature beats triggered ventricular arrhythmias during pilsicainide infusion in a patient with inferior ST-segment elevation.
Topics: Adolescent; Anti-Arrhythmia Agents; Atrial Flutter; Electrocardiography; Humans; Infusions, Intraven | 2006 |
Re: Clinical significance of macroscopic T-wave alternans after sodium channel blocker administration in patients with Brugada syndrome.
Topics: Brugada Syndrome; Electrocardiography; Female; Humans; Lidocaine; Male; Middle Aged; Sodium Channel | 2008 |
Idiopathic ventricular fibrillation initiated by a short-coupled ventricular premature beat.
Topics: Adult; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Drug Therapy, Combination; Electrocardi | 1996 |
Relatively benign clinical course in asymptomatic patients with brugada-type electrocardiogram without family history of sudden death.
Topics: Adult; Anti-Arrhythmia Agents; Bundle-Branch Block; Death, Sudden, Cardiac; Electrocardiography; Ele | 2001 |
Paradoxic abbreviation of repolarization in epicardium of the right ventricular outflow tract during augmentation of Brugada-type ST segment elevation.
Topics: Anti-Arrhythmia Agents; Bundle-Branch Block; Cardiotonic Agents; Electrocardiography; Heart Ventricl | 2001 |
J wave and ST segment elevation in the inferior leads: a latent type of variant Brugada syndrome?
Topics: Adult; Bundle-Branch Block; Diagnosis, Differential; Electrocardiography; Humans; Lidocaine; Male; S | 2002 |